Wikidata

(Q21114033)

English

Tumor susceptibility 101

mammalian protein found in Homo sapiens

  • tumor susceptibility gene 101
  • tumor susceptibility gene 101 protein
  • tumor susceptibility gene 10
  • tumor susceptibility protein
  • ESCRT-I complex subunit TSG101
  • TSG101
In more languages

Statements

molecular function
protein binding
determination method
IPI
23 references
retrieved
8 April 2019
stated in
Formation and release of arrestin domain-containing protein 1-mediated microvesicles (ARMMs) at plasma membrane by recruitment of TSG101 protein
GOA
curator
UniProt
UniProt protein ID
Q99816
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99816
determination method
IPI
retrieved
8 April 2019
stated in
Identification of Alix-type and Non-Alix-type ALG-2-binding sites in human phospholipid scramblase 3: differential binding to an alternatively spliced isoform and amino acid-substituted mutants
GOA
curator
UniProt
UniProt protein ID
Q99816
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99816
determination method
IPI
retrieved
8 April 2019
stated in
The human endosomal sorting complex required for transport (ESCRT-I) and its role in HIV-1 budding
GOA
curator
UniProt
UniProt protein ID
Q99816
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99816
determination method
IPI
retrieved
8 April 2019
stated in
The Protein Network of HIV Budding
GOA
curator
UniProt
UniProt protein ID
Q99816
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99816
determination method
IPI
retrieved
8 April 2019
stated in
Human ESCRT-II complex and its role in human immunodeficiency virus type 1 release
GOA
curator
UniProt
UniProt protein ID
Q99816
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99816
determination method
IPI
retrieved
8 April 2019
stated in
Differential requirements for Alix and ESCRT-III in cytokinesis and HIV-1 release
GOA
curator
UniProt
UniProt protein ID
Q99816
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99816
determination method
IPI
retrieved
8 April 2019
stated in
Identification of human MVB12 proteins as ESCRT-I subunits that function in HIV budding
GOA
curator
UniProt
UniProt protein ID
Q99816
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99816
determination method
IPI
retrieved
8 April 2019
stated in
Regulation of Tsg101 expression by the steadiness box: a role of Tsg101-associated ligase
GOA
curator
UniProt
UniProt protein ID
Q99816
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99816
determination method
IPI
retrieved
8 April 2019
stated in
Divergent retroviral late-budding domains recruit vacuolar protein sorting factors by using alternative adaptor proteins
GOA
curator
UniProt
UniProt protein ID
Q99816
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99816
determination method
IPI
retrieved
8 April 2019
stated in
Hrs regulates multivesicular body formation via ESCRT recruitment to endosomes
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99816
determination method
IPI
retrieved
8 April 2019
stated in
HD-PTP and Alix share some membrane-traffic related proteins that interact with their Bro1 domains or proline-rich regions
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99816
determination method
IPI
retrieved
8 April 2019
stated in
TSG101 interaction with HRS mediates endosomal trafficking and receptor down-regulation
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99816
determination method
IPI
retrieved
8 April 2019
stated in
Human ESCRT and ALIX proteins interact with proteins of the midbody and function in cytokinesis
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99816
determination method
IPI
retrieved
8 April 2019
stated in
Towards a proteome-scale map of the human protein–protein interaction network
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99816
determination method
IPI
retrieved
8 April 2019
stated in
A proteome-scale map of the human interactome network
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99816
determination method
IPI
retrieved
8 April 2019
stated in
TEX14 interacts with CEP55 to block cell abscission
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99816
determination method
IPI
retrieved
8 April 2019
stated in
Physical and functional interactions between Daxx and TSG101
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99816
determination method
IPI
retrieved
8 April 2019
stated in
SIMPLE interacts with NEDD4 and TSG101: evidence for a role in lysosomal sorting and implications for Charcot-Marie-Tooth disease
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99816
determination method
IPI
retrieved
8 April 2019
stated in
Analysis of the human E2 ubiquitin conjugating enzyme protein interaction network
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99816
determination method
IPI
retrieved
8 April 2019
stated in
An empirical framework for binary interactome mapping
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99816
determination method
IPI
retrieved
8 April 2019
stated in
Pooled-matrix protein interaction screens using Barcode Fusion Genetics
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99816
determination method
IPI
retrieved
8 April 2019
stated in
Widespread Expansion of Protein Interaction Capabilities by Alternative Splicing
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99816
determination method
IPI
retrieved
8 April 2019
stated in
Interactions of TOM1L1 with the multivesicular body sorting machinery
GOA
curator
HUGO Gene Nomenclature Committee
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99816
determination method
IPI
cell component
extracellular exosome
determination method
IDA
6 references
retrieved
31 October 2017
stated in
In-depth proteomic analyses of exosomes isolated from expressed prostatic secretions in urine
GOA
curator
UniProt
UniProt protein ID
Q99816
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=Q99816&geneProductId=UniProtKB:Q99816
determination method
IDA
retrieved
31 October 2017
stated in
Identification and proteomic profiling of exosomes in human urine
GOA
curator
UniProt
UniProt protein ID
Q99816
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=Q99816&geneProductId=UniProtKB:Q99816
determination method
IDA
retrieved
31 October 2017
stated in
Collection, storage, preservation, and normalization of human urinary exosomes for biomarker discovery
GOA
curator
UniProt
UniProt protein ID
Q99816
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=Q99816&geneProductId=UniProtKB:Q99816
determination method
IDA
retrieved
31 October 2017
stated in
Monitoring the Rab27 associated exosome pathway using nanoparticle tracking analysis
GOA
curator
UniProt
UniProt protein ID
Q99816
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=Q99816&geneProductId=UniProtKB:Q99816
determination method
IDA
retrieved
31 October 2017
stated in
Large-scale proteomics and phosphoproteomics of urinary exosomes
GOA
curator
UniProt
UniProt protein ID
Q99816
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=Q99816&geneProductId=UniProtKB:Q99816
determination method
IDA
retrieved
31 October 2017
stated in
Proteomic analysis of podocyte exosome-enriched fraction from normal human urine
GOA
curator
UniProt
UniProt protein ID
Q99816
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=Q99816&geneProductId=UniProtKB:Q99816
determination method
IDA
ESCRT I complex
determination method
IDA
TAS
6 references
retrieved
8 April 2019
stated in
Membrane budding and scission by the ESCRT machinery: it's all in the neck
GOA
curator
Parkinsons Disease Gene Ontology Initiative
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99816
determination method
TAS
retrieved
8 April 2019
stated in
The role of ESCRT proteins in fusion events involving lysosomes, endosomes and autophagosomes
GOA
curator
Parkinsons Disease Gene Ontology Initiative
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99816
determination method
TAS
retrieved
8 April 2019
stated in
UBAP1 is a component of an endosome-specific ESCRT-I complex that is essential for MVB sorting
GOA
curator
UniProt
UniProt protein ID
Q99816
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99816
determination method
IDA
retrieved
8 April 2019
stated in
Distinct functions of human MVB12A and MVB12B in the ESCRT-I dependent on their posttranslational modifications
GOA
curator
UniProt
UniProt protein ID
Q99816
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99816
determination method
IDA
retrieved
8 April 2019
stated in
Structural basis for membrane targeting by the MVB12-associated β-prism domain of the human ESCRT-I MVB12 subunit
GOA
curator
UniProt
UniProt protein ID
Q99816
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99816
determination method
IDA
retrieved
8 April 2019
stated in
Identification of human MVB12 proteins as ESCRT-I subunits that function in HIV budding
GOA
curator
UniProt
UniProt protein ID
Q99816
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99816
determination method
IDA
extracellular exosome
determination method
HDA
IDA
IEA
6 references
retrieved
8 April 2019
stated in
GOA
curator
Ensembl genome database project
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99816
determination method
IEA
retrieved
8 April 2019
stated in
Collection, storage, preservation, and normalization of human urinary exosomes for biomarker discovery
GOA
curator
UniProt
UniProt protein ID
Q99816
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99816
determination method
IDA
retrieved
8 April 2019
stated in
Monitoring the Rab27 associated exosome pathway using nanoparticle tracking analysis
GOA
curator
UniProt
UniProt protein ID
Q99816
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99816
determination method
IDA
retrieved
8 April 2019
stated in
Identification and proteomic profiling of exosomes in human urine
GOA
curator
UniProt
UniProt protein ID
Q99816
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99816
determination method
IDA
retrieved
8 April 2019
stated in
Large-scale proteomics and phosphoproteomics of urinary exosomes
GOA
curator
UniProt
UniProt protein ID
Q99816
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99816
determination method
HDA
retrieved
8 April 2019
stated in
In-depth proteomic analyses of exosomes isolated from expressed prostatic secretions in urine
GOA
curator
UniProt
UniProt protein ID
Q99816
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99816
determination method
HDA
biological process

Identifiers

PDB structure ID
 
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