(Q21114173)

Armadillo-type fold

1 reference

TOG domain, protein family

1 reference

based on heuristic

inferred from protein domain or family

CLASP N-terminal domain, protein family

1 reference

based on heuristic

inferred from protein domain or family

1 reference

13 November 2019

1 reference

13 November 2019

protein tyrosine kinase binding

1 reference

26 September 2017

Abelson phosphorylation of CLASP2 modulates its association with microtubules and actin

http://www.ebi.ac.uk/QuickGO/annotations?protein=O75122&geneProductId=UniProtKB:O75122

dystroglycan binding

1 reference

8 April 2019

Epiblast integrity requires CLASP and Dystroglycan-mediated microtubule anchoring to the basal cortex

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O75122

microtubule binding

1 reference

8 April 2019

CLASP2 Has Two Distinct TOG Domains That Contribute Differently to Microtubule Dynamics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O75122

microtubule plus-end binding

actin filament binding

1 reference

26 September 2017

Abelson phosphorylation of CLASP2 modulates its association with microtubules and actin

http://www.ebi.ac.uk/QuickGO/annotations?protein=O75122&geneProductId=UniProtKB:O75122

protein binding

6 references

8 April 2019

An EB1-binding motif acts as a microtubule tip localization signal

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O75122

8 April 2019

Asymmetric CLASP-dependent nucleation of noncentrosomal microtubules at the trans-Golgi network

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O75122

8 April 2019

Clasps are CLIP-115 and -170 associating proteins involved in the regional regulation of microtubule dynamics in motile fibroblasts

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O75122

8 April 2019

An EB1-binding motif acts as a microtubule tip localization signal

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O75122

8 April 2019

An organelle-specific protein landscape identifies novel diseases and molecular mechanisms

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O75122

8 April 2019

A human interactome in three quantitative dimensions organized by stoichiometries and abundances

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O75122

cell component

Golgi apparatus

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O75122

3 references

8 April 2019

8 April 2019

Clasps are CLIP-115 and -170 associating proteins involved in the regional regulation of microtubule dynamics in motile fibroblasts

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O75122

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O75122

8 April 2019

cell projection

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O75122

1 reference

8 April 2019

kinetochore microtubule

1 reference

8 April 2019

Human CLASP1 is an outer kinetochore component that regulates spindle microtubule dynamics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O75122

focal adhesion

1 reference

8 April 2019

CLASPs link focal-adhesion-associated microtubule capture to localized exocytosis and adhesion site turnover

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O75122

axonal growth cone

1 reference

26 September 2017

Abelson phosphorylation of CLASP2 modulates its association with microtubules and actin

http://www.ebi.ac.uk/QuickGO/annotations?protein=O75122&geneProductId=UniProtKB:O75122

spindle

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O75122

1 reference

8 April 2019

microtubule organizing center

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O75122

1 reference

8 April 2019

chromosome

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O75122

1 reference

8 April 2019

trans-Golgi network

1 reference

8 April 2019

Asymmetric CLASP-dependent nucleation of noncentrosomal microtubules at the trans-Golgi network

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O75122

cell cortex

1 reference

8 April 2019

Role of CLASP2 in microtubule stabilization and the regulation of persistent motility

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O75122

cell leading edge

1 reference

8 April 2019

CLASPs link focal-adhesion-associated microtubule capture to localized exocytosis and adhesion site turnover

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O75122

cortical microtubule plus-end

1 reference

26 September 2017

Abelson phosphorylation of CLASP2 modulates its association with microtubules and actin

http://www.ebi.ac.uk/QuickGO/annotations?protein=O75122&geneProductId=UniProtKB:O75122

cytoplasmic microtubule

1 reference

8 April 2019

Clasps are CLIP-115 and -170 associating proteins involved in the regional regulation of microtubule dynamics in motile fibroblasts

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O75122

mitotic spindle

1 reference

8 April 2019

Mammalian CLASPs are required for mitotic spindle organization and kinetochore alignment

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O75122

basal cortex

1 reference

8 April 2019

Epiblast integrity requires CLASP and Dystroglycan-mediated microtubule anchoring to the basal cortex

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O75122

microtubule

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O75122

4 references

8 April 2019

8 April 2019

CLASPs link focal-adhesion-associated microtubule capture to localized exocytosis and adhesion site turnover

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O75122

8 April 2019

Asymmetric CLASP-dependent nucleation of noncentrosomal microtubules at the trans-Golgi network

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O75122

8 April 2019

ErbB2 receptor controls microtubule capture by recruiting ACF7 to the plasma membrane of migrating cells

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O75122

chromosome, centromeric region

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O75122

1 reference

8 April 2019

cytoskeleton

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O75122

1 reference

8 April 2019

biological process

vesicle targeting

1 reference

8 April 2019

CLASPs link focal-adhesion-associated microtubule capture to localized exocytosis and adhesion site turnover

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O75122

regulation of actin cytoskeleton organization

1 reference

26 September 2017

Abelson phosphorylation of CLASP2 modulates its association with microtubules and actin

http://www.ebi.ac.uk/QuickGO/annotations?protein=O75122&geneProductId=UniProtKB:O75122

regulation of axon extension

1 reference

26 September 2017

Abelson phosphorylation of CLASP2 modulates its association with microtubules and actin

http://www.ebi.ac.uk/QuickGO/annotations?protein=O75122&geneProductId=UniProtKB:O75122

Golgi organization

1 reference

8 April 2019

CLASPs link focal-adhesion-associated microtubule capture to localized exocytosis and adhesion site turnover

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O75122

mitotic spindle organization

1 reference

8 April 2019

Mammalian CLASPs are required for mitotic spindle organization and kinetochore alignment

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O75122

regulation of epithelial to mesenchymal transition

1 reference

8 April 2019

Epiblast integrity requires CLASP and Dystroglycan-mediated microtubule anchoring to the basal cortex

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O75122

positive regulation of epithelial cell migration

1 reference

8 April 2019

CLASPs link focal-adhesion-associated microtubule capture to localized exocytosis and adhesion site turnover

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O75122

exit from mitosis

1 reference

8 April 2019

Mammalian CLASPs are required for mitotic spindle organization and kinetochore alignment

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O75122

cell division

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O75122

1 reference

8 April 2019

establishment or maintenance of cell polarity

1 reference

8 April 2019

CLIPs and CLASPs and cellular dynamics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O75122

positive regulation of extracellular matrix disassembly

1 reference

8 April 2019

CLASPs link focal-adhesion-associated microtubule capture to localized exocytosis and adhesion site turnover

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O75122

positive regulation of basement membrane assembly involved in embryonic body morphogenesis

1 reference

8 April 2019

Epiblast integrity requires CLASP and Dystroglycan-mediated microtubule anchoring to the basal cortex

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O75122

negative regulation of microtubule depolymerization

NAS

1 reference

8 April 2019

Clasps are CLIP-115 and -170 associating proteins involved in the regional regulation of microtubule dynamics in motile fibroblasts

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O75122

NAS

microtubule anchoring

regulation of microtubule-based process

1 reference

8 April 2019

ErbB2 receptor controls microtubule capture by recruiting ACF7 to the plasma membrane of migrating cells

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O75122

regulation of microtubule polymerization

1 reference

26 September 2017

Abelson phosphorylation of CLASP2 modulates its association with microtubules and actin

http://www.ebi.ac.uk/QuickGO/annotations?protein=O75122&geneProductId=UniProtKB:O75122

regulation of microtubule polymerization or depolymerization

1 reference

8 April 2019

Clasps are CLIP-115 and -170 associating proteins involved in the regional regulation of microtubule dynamics in motile fibroblasts

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O75122

negative regulation of wound healing, spreading of epidermal cells

1 reference

8 April 2019

CLASPs link focal-adhesion-associated microtubule capture to localized exocytosis and adhesion site turnover

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O75122

cell cycle

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O75122

1 reference

8 April 2019

positive regulation of exocytosis

1 reference

8 April 2019

CLASPs link focal-adhesion-associated microtubule capture to localized exocytosis and adhesion site turnover

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O75122

negative regulation of stress fiber assembly

1 reference

8 April 2019

CLASPs link focal-adhesion-associated microtubule capture to localized exocytosis and adhesion site turnover

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O75122

microtubule organizing center organization

1 reference

8 April 2019

Asymmetric CLASP-dependent nucleation of noncentrosomal microtubules at the trans-Golgi network

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O75122

negative regulation of focal adhesion assembly

1 reference

8 April 2019

CLASPs link focal-adhesion-associated microtubule capture to localized exocytosis and adhesion site turnover

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O75122

regulation of gastrulation

1 reference

8 April 2019

Epiblast integrity requires CLASP and Dystroglycan-mediated microtubule anchoring to the basal cortex

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O75122

microtubule cytoskeleton organization

microtubule nucleation

1 reference

8 April 2019

Asymmetric CLASP-dependent nucleation of noncentrosomal microtubules at the trans-Golgi network

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O75122

platelet-derived growth factor receptor-beta signaling pathway

1 reference

26 September 2017

Abelson phosphorylation of CLASP2 modulates its association with microtubules and actin

http://www.ebi.ac.uk/QuickGO/annotations?protein=O75122&geneProductId=UniProtKB:O75122

sister chromatid cohesion

http://www.ebi.ac.uk/QuickGO/annotations?protein=O75122&geneProductId=UniProtKB:O75122

1 reference

26 September 2017

protein localization to plasma membrane

1 reference

8 April 2019

Epiblast integrity requires CLASP and Dystroglycan-mediated microtubule anchoring to the basal cortex

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O75122

has part(s)

CLASP N-terminal domain

1 reference

TOG domain

1 reference