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Major histocompatibility complex, class II, DO alpha
mammalian protein found in Homo sapiens
MHC DZ alpha
HLA-D0-alpha
MHC class II antigen DOA
lymphocyte antigen
HLA-DOA
HLA class II histocompatibility antigen, DO alpha chain
MHC DN-alpha
major histocompatibility complex, class II, DN alpha
In more languages
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Statements
instance of
protein
1 reference
stated in
UniProt
retrieved
13 November 2019
UniProt protein ID
P06340
part of
Immunoglobulin-like fold
1 reference
stated in
InterPro Release 71.0
reference URL
http://www.ebi.ac.uk/interpro/protein/P06340
Immunoglobulin-like domain superfamily
1 reference
stated in
InterPro Release 71.0
reference URL
http://www.ebi.ac.uk/interpro/protein/P06340
MHC classes I/II-like antigen recognition protein
1 reference
stated in
InterPro Release 71.0
reference URL
http://www.ebi.ac.uk/interpro/protein/P06340
MHC class II, alpha/beta chain, N-terminal
1 reference
stated in
InterPro Release 71.0
reference URL
http://www.ebi.ac.uk/interpro/protein/P06340
MHC class II, alpha chain, N-terminal domain, protein family
1 reference
based on heuristic
inferred from protein domain or family
Immunoglobulin C1-set, protein family
1 reference
based on heuristic
inferred from protein domain or family
immunoglobulin-like domain, protein family
1 reference
based on heuristic
inferred from protein domain or family
Immunoglobulin/major histocompatibility complex, conserved site, protein family
1 reference
based on heuristic
inferred from protein domain or family
found in taxon
Homo sapiens
1 reference
stated in
UniProt
retrieved
13 November 2019
UniProt protein ID
P06340
encoded by
HLA-DOA
1 reference
stated in
UniProt
retrieved
13 November 2019
UniProt protein ID
P06340
molecular function
MHC class II receptor activity
determination method
TAS
1 reference
retrieved
9 May 2019
stated in
The human HLA class II alpha chain gene DZ alpha is distinct from genes in the DP, DQ and DR subregions
GOA
curator
UniProt
UniProt protein ID
P06340
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P06340
determination method
TAS
protein binding
determination method
IPI
1 reference
retrieved
9 May 2019
stated in
A proteome-scale map of the human interactome network
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P06340
determination method
IPI
MHC class II protein complex binding
determination method
IDA
1 reference
retrieved
9 May 2019
stated in
Mapping the HLA-DO/HLA-DM complex by FRET and mutagenesis
GOA
curator
UniProt
UniProt protein ID
P06340
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P06340
determination method
IDA
cell component
integral component of membrane
determination method
IEA
1 reference
retrieved
9 May 2019
stated in
GOA
curator
UniProt
UniProt protein ID
P06340
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P06340
determination method
IEA
lysosomal membrane
determination method
TAS
IEA
2 references
retrieved
9 May 2019
stated in
GOA
curator
Reactome
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P06340
determination method
TAS
retrieved
9 May 2019
stated in
GOA
curator
UniProt
UniProt protein ID
P06340
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P06340
determination method
IEA
endosome
determination method
IEA
1 reference
retrieved
9 May 2019
stated in
GOA
curator
UniProt
UniProt protein ID
P06340
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P06340
determination method
IEA
plasma membrane
determination method
TAS
1 reference
retrieved
9 May 2019
stated in
The human HLA class II alpha chain gene DZ alpha is distinct from genes in the DP, DQ and DR subregions
GOA
curator
Proteome Inc.
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P06340
determination method
TAS
lysosome
determination method
IEA
1 reference
retrieved
9 May 2019
stated in
GOA
curator
UniProt
UniProt protein ID
P06340
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P06340
determination method
IEA
MHC class II protein complex
determination method
IDA
IEA
3 references
retrieved
9 May 2019
stated in
GOA
curator
UniProt
UniProt protein ID
P06340
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P06340
determination method
IEA
retrieved
9 May 2019
stated in
GOA
curator
InterPro
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P06340
determination method
IEA
retrieved
9 May 2019
stated in
Mapping the HLA-DO/HLA-DM complex by FRET and mutagenesis
GOA
curator
UniProt
UniProt protein ID
P06340
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P06340
determination method
IDA
endosome membrane
determination method
IEA
1 reference
retrieved
9 May 2019
stated in
GOA
curator
UniProt
UniProt protein ID
P06340
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P06340
determination method
IEA
membrane
determination method
IEA
2 references
retrieved
9 May 2019
stated in
GOA
curator
UniProt
UniProt protein ID
P06340
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P06340
determination method
IEA
retrieved
9 May 2019
stated in
GOA
curator
InterPro
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P06340
determination method
IEA
biological process
antigen processing and presentation of peptide or polysaccharide antigen via MHC class II
determination method
IEA
1 reference
retrieved
9 May 2019
stated in
GOA
curator
UniProt
UniProt protein ID
P06340
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P06340
determination method
IEA
antigen processing and presentation
determination method
IEA
2 references
retrieved
9 May 2019
stated in
GOA
curator
InterPro
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P06340
determination method
IEA
retrieved
9 May 2019
stated in
GOA
curator
Ensembl genome database project
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P06340
determination method
IEA
antigen processing and presentation of exogenous peptide antigen via MHC class II
determination method
TAS
IEA
2 references
retrieved
9 May 2019
stated in
GOA
curator
Reactome
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P06340
determination method
TAS
retrieved
9 May 2019
stated in
GOA
curator
Ensembl genome database project
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P06340
determination method
IEA
immune response
determination method
IEA
1 reference
retrieved
9 May 2019
stated in
GOA
curator
InterPro
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P06340
determination method
IEA
negative regulation of antigen processing and presentation of peptide antigen via MHC class II
determination method
IDA
1 reference
retrieved
9 May 2019
stated in
Mapping the HLA-DO/HLA-DM complex by FRET and mutagenesis
GOA
curator
UniProt
UniProt protein ID
P06340
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P06340
determination method
IDA
regulation of T cell differentiation
determination method
IEA
1 reference
retrieved
9 May 2019
stated in
GOA
curator
Ensembl genome database project
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P06340
determination method
IEA
immune system process
determination method
IEA
1 reference
retrieved
9 May 2019
stated in
GOA
curator
UniProt
UniProt protein ID
P06340
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P06340
determination method
IEA
signal transduction
determination method
IEA
1 reference
retrieved
27 March 2018
stated in
GOA
curator
Gene Ontology Consortium
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P06340&geneProductId=UniProtKB:P06340
determination method
IEA
adaptive immune response
determination method
IEA
1 reference
retrieved
9 May 2019
stated in
GOA
curator
UniProt
UniProt protein ID
P06340
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P06340
determination method
IEA
has part(s)
immunoglobulin C1-set
1 reference
stated in
InterPro Release 71.0
reference URL
http://www.ebi.ac.uk/interpro/protein/P06340
immunoglobulin-like domain
1 reference
stated in
InterPro Release 71.0
reference URL
http://www.ebi.ac.uk/interpro/protein/P06340
Immunoglobulin/major histocompatibility complex, conserved site
1 reference
stated in
InterPro Release 71.0
reference URL
http://www.ebi.ac.uk/interpro/protein/P06340
MHC class II, alpha chain, N-terminal
1 reference
stated in
InterPro Release 71.0
reference URL
http://www.ebi.ac.uk/interpro/protein/P06340
Identifiers
RefSeq protein ID
NP_002110
1 reference
stated in
NCBI Gene
retrieved
30 May 2020
Entrez Gene ID
3111
UniProt protein ID
P06340
1 reference
stated in
UniProt
retrieved
13 November 2019
UniProt protein ID
P06340
Ensembl protein ID
ENSP00000229829
1 reference
stated in
Ensembl Release 99
Ensembl protein ID
ENSP00000229829
ENSP00000372713
1 reference
stated in
Ensembl Release 99
Ensembl protein ID
ENSP00000372713
ENSP00000395737
1 reference
stated in
Ensembl Release 99
Ensembl protein ID
ENSP00000395737
ENSP00000397945
1 reference
stated in
Ensembl Release 99
Ensembl protein ID
ENSP00000397945
ENSP00000398819
1 reference
stated in
Ensembl Release 99
Ensembl protein ID
ENSP00000398819
ENSP00000401504
1 reference
stated in
Ensembl Release 99
Ensembl protein ID
ENSP00000401504
ENSP00000416448
1 reference
stated in
Ensembl Release 99
Ensembl protein ID
ENSP00000416448
ENSP00000405153
1 reference
stated in
Ensembl Release 99
Ensembl protein ID
ENSP00000405153
ENSP00000372712
1 reference
stated in
Ensembl Release 99
Ensembl protein ID
ENSP00000372712
ENSP00000402076
1 reference
stated in
Ensembl Release 99
Ensembl protein ID
ENSP00000402076
ENSP00000402487
1 reference
stated in
Ensembl Release 99
Ensembl protein ID
ENSP00000402487
ENSP00000402347
1 reference
stated in
Ensembl Release 99
Ensembl protein ID
ENSP00000402347
ENSP00000363946
1 reference
stated in
Ensembl Release 99
Ensembl protein ID
ENSP00000363946
ENSP00000409491
1 reference
stated in
Ensembl Release 99
Ensembl protein ID
ENSP00000409491
PDB structure ID
4I0P
1 reference
stated in
UniProt
UniProt protein ID
P06340
retrieved
9 August 2016
language of work or name
English
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