Wikidata

(Q21115219)

English

Nuclear receptor subfamily 1 group H member 2

mammalian protein found in Homo sapiens

  • steroid hormone-nuclear receptor NER
  • ubiquitously-expressed nuclear receptor
  • liver X nuclear receptor beta
  • nuclear orphan receptor LXR-beta
  • Liver X receptor beta
  • nuclear receptor NER
  • LX receptor beta
  • oxysterols receptor LXR-beta
  • NR1H2
In more languages

Statements

molecular function
protein binding
determination method
IPI
7 references
retrieved
8 April 2019
stated in
CCAR2 negatively regulates nuclear receptor LXRα by competing with SIRT1 deacetylase
GOA
curator
UniProt
UniProt protein ID
P55055
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P55055
determination method
IPI
retrieved
8 April 2019
stated in
ABCA12 regulates ABCA1-dependent cholesterol efflux from macrophages and the development of atherosclerosis
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P55055
determination method
IPI
retrieved
8 April 2019
stated in
Coronin 2A mediates actin-dependent de-repression of inflammatory response genes
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P55055
determination method
IPI
retrieved
8 April 2019
stated in
Broad Anti-tumor Activity of a Small Molecule that Selectively Targets the Warburg Effect and Lipogenesis
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P55055
determination method
IPI
retrieved
8 April 2019
stated in
Towards a proteome-scale map of the human protein–protein interaction network
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P55055
determination method
IPI
retrieved
8 April 2019
stated in
An empirical framework for binary interactome mapping
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P55055
determination method
IPI
retrieved
8 April 2019
stated in
Regulation of ALK-1 signaling by the nuclear receptor LXRbeta
GOA
curator
HUGO Gene Nomenclature Committee
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P55055
determination method
IPI
cell component
biological process
positive regulation of transcription by RNA polymerase II
determination method
IDA
IEA
IMP
5 references
retrieved
24 April 2018
stated in
Selective up-regulation of LXR-regulated genes ABCA1, ABCG1, and APOE in macrophages through increased endogenous synthesis of 24(S),25-epoxycholesterol
GOA
curator
British Heart Foundation
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P55055&geneProductId=UniProtKB:P55055
determination method
IMP
retrieved
24 April 2018
stated in
GOA
curator
Ensembl genome database project
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P55055&geneProductId=UniProtKB:P55055
determination method
IEA
retrieved
24 April 2018
stated in
Activation of LXR increases acyl-CoA synthetase activity through direct regulation of ACSL3 in human placental trophoblast cells
GOA
curator
UniProt
UniProt protein ID
P55055
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P55055&geneProductId=UniProtKB:P55055
determination method
IDA
retrieved
24 April 2018
stated in
Activation of the nuclear receptor LXR by oxysterols defines a new hormone response pathway
GOA
curator
Norwegian University of Science and Technology, Systems Biology team
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P55055&geneProductId=UniProtKB:P55055
determination method
IDA
retrieved
24 April 2018
stated in
Liver X receptor activation controls intracellular cholesterol trafficking and esterification in human macrophages
GOA
curator
British Heart Foundation
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P55055&geneProductId=UniProtKB:P55055
determination method
IDA
positive regulation of transcription by RNA polymerase II
determination method
IBA
IDA
IEA
IMP
6 references
retrieved
1 January 2018
stated in
Selective up-regulation of LXR-regulated genes ABCA1, ABCG1, and APOE in macrophages through increased endogenous synthesis of 24(S),25-epoxycholesterol
GOA
curator
British Heart Foundation
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P55055
determination method
IMP
retrieved
1 January 2018
stated in
GOA
curator
Ensembl genome database project
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P55055
determination method
IEA
retrieved
1 January 2018
stated in
Activation of LXR increases acyl-CoA synthetase activity through direct regulation of ACSL3 in human placental trophoblast cells
GOA
curator
UniProt
UniProt protein ID
P55055
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P55055
determination method
IDA
retrieved
1 January 2018
stated in
Activation of the nuclear receptor LXR by oxysterols defines a new hormone response pathway
GOA
curator
Norwegian University of Science and Technology, Systems Biology team
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P55055
determination method
IDA
retrieved
1 January 2018
stated in
Liver X receptor activation controls intracellular cholesterol trafficking and esterification in human macrophages
GOA
curator
British Heart Foundation
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P55055
determination method
IDA
retrieved
1 January 2018
stated in
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
GOA
curator
GO Central
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P55055
determination method
IBA
positive regulation of transcription by RNA polymerase II
determination method
IBA
IDA
IMP
5 references
retrieved
8 April 2019
stated in
Selective up-regulation of LXR-regulated genes ABCA1, ABCG1, and APOE in macrophages through increased endogenous synthesis of 24(S),25-epoxycholesterol
GOA
curator
British Heart Foundation
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P55055
determination method
IMP
retrieved
8 April 2019
stated in
Activation of LXR increases acyl-CoA synthetase activity through direct regulation of ACSL3 in human placental trophoblast cells
GOA
curator
UniProt
UniProt protein ID
P55055
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P55055
determination method
IDA
retrieved
8 April 2019
stated in
Activation of the nuclear receptor LXR by oxysterols defines a new hormone response pathway
GOA
curator
Norwegian University of Science and Technology, Systems Biology team
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P55055
determination method
IDA
retrieved
8 April 2019
stated in
Liver X receptor activation controls intracellular cholesterol trafficking and esterification in human macrophages
GOA
curator
British Heart Foundation
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P55055
determination method
IDA
retrieved
8 April 2019
stated in
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
GOA
curator
GO Central
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P55055
determination method
IBA

Identifiers

PDB structure ID
 
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