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(Q21115476)
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English
Heat shock protein family B (small) member 8
mammalian protein found in Homo sapiens
small stress protein-like protein HSP22
heat shock 22kDa protein 8
E2-induced gene 1 protein
heat shock protein beta-8
alpha-crystallin C chain
protein kinase H11
heat shock 27kDa protein 8
HSPB8
In more languages
edit
Statements
instance of
protein
1 reference
stated in
UniProt
retrieved
13 November 2019
UniProt protein ID
Q9UJY1
part of
HSP20-like chaperone
1 reference
stated in
InterPro Release 71.0
reference URL
http://www.ebi.ac.uk/interpro/protein/Q9UJY1
Alpha crystallin/Heat shock protein
1 reference
stated in
InterPro Release 71.0
reference URL
http://www.ebi.ac.uk/interpro/protein/Q9UJY1
Alpha crystallin/Hsp20 domain, protein family
1 reference
based on heuristic
inferred from protein domain or family
found in taxon
Homo sapiens
1 reference
stated in
UniProt
retrieved
13 November 2019
UniProt protein ID
Q9UJY1
encoded by
HSPB8
1 reference
stated in
UniProt
retrieved
13 November 2019
UniProt protein ID
Q9UJY1
molecular function
protein kinase activity
determination method
IDA
1 reference
retrieved
8 April 2019
stated in
Some properties of human small heat shock protein Hsp22 (H11 or HspB8)
GOA
curator
UniProt
UniProt protein ID
Q9UJY1
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9UJY1
determination method
IDA
protein binding
determination method
IPI
10 references
retrieved
8 April 2019
stated in
Axonal Neuropathies due to Mutations in Small Heat Shock Proteins: Clinical, Genetic, and Functional Insights into Novel Mutations
GOA
curator
UniProt
UniProt protein ID
Q9UJY1
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9UJY1
determination method
IPI
retrieved
8 April 2019
stated in
Mutations affecting the cytoplasmic functions of the co-chaperone DNAJB6 cause limb-girdle muscular dystrophy
GOA
curator
UniProt
UniProt protein ID
Q9UJY1
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9UJY1
determination method
IPI
retrieved
8 April 2019
stated in
A human interactome in three quantitative dimensions organized by stoichiometries and abundances
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9UJY1
determination method
IPI
retrieved
8 April 2019
stated in
Next-generation sequencing to generate interactome datasets
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9UJY1
determination method
IPI
retrieved
8 April 2019
stated in
Towards a proteome-scale map of the human protein–protein interaction network
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9UJY1
determination method
IPI
retrieved
8 April 2019
stated in
A proteome-scale map of the human interactome network
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9UJY1
determination method
IPI
retrieved
8 April 2019
stated in
Interaction of human HSP22 (HSPB8) with other small heat shock proteins
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9UJY1
determination method
IPI
retrieved
8 April 2019
stated in
Interactions of HSP22 (HSPB8) with HSP20, alphaB-crystallin, and HSPB3
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9UJY1
determination method
IPI
retrieved
8 April 2019
stated in
A quantitative chaperone interaction network reveals the architecture of cellular protein homeostasis pathways
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9UJY1
determination method
IPI
retrieved
8 April 2019
stated in
HspB8 chaperone activity toward poly(Q)-containing proteins depends on its association with Bag3, a stimulator of macroautophagy.
GOA
curator
ARUK-UCL
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9UJY1
determination method
IPI
identical protein binding
determination method
IPI
1 reference
retrieved
8 April 2019
stated in
Interaction of human HSP22 (HSPB8) with other small heat shock proteins
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9UJY1
determination method
IPI
protein homodimerization activity
determination method
IDA
1 reference
retrieved
8 April 2019
stated in
HspB8 chaperone activity toward poly(Q)-containing proteins depends on its association with Bag3, a stimulator of macroautophagy.
GOA
curator
ARUK-UCL
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9UJY1
determination method
IDA
cell component
cytoplasm
determination method
IDA
IEA
3 references
retrieved
8 April 2019
stated in
GOA
curator
UniProt
UniProt protein ID
Q9UJY1
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9UJY1
determination method
IEA
retrieved
8 April 2019
stated in
Axonal Neuropathies due to Mutations in Small Heat Shock Proteins: Clinical, Genetic, and Functional Insights into Novel Mutations
GOA
curator
UniProt
UniProt protein ID
Q9UJY1
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9UJY1
determination method
IDA
retrieved
8 April 2019
stated in
HSPB7 is a SC35 speckle resident small heat shock protein
GOA
curator
UniProt
UniProt protein ID
Q9UJY1
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9UJY1
determination method
IDA
intracellular anatomical structure
determination method
IDA
1 reference
retrieved
8 April 2019
stated in
GOA
curator
LifeDB
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9UJY1
determination method
IDA
nucleus
determination method
IDA
IEA
2 references
retrieved
8 April 2019
stated in
GOA
curator
UniProt
UniProt protein ID
Q9UJY1
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9UJY1
determination method
IEA
retrieved
8 April 2019
stated in
HSPB7 is a SC35 speckle resident small heat shock protein
GOA
curator
UniProt
UniProt protein ID
Q9UJY1
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9UJY1
determination method
IDA
nucleoplasm
determination method
TAS
1 reference
retrieved
8 April 2019
stated in
GOA
curator
Reactome
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9UJY1
determination method
TAS
cytosol
determination method
IDA
1 reference
retrieved
8 April 2019
stated in
GOA
curator
Human Protein Atlas
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9UJY1
determination method
IDA
chaperone complex
determination method
IDA
1 reference
retrieved
8 April 2019
stated in
HspB8 chaperone activity toward poly(Q)-containing proteins depends on its association with Bag3, a stimulator of macroautophagy.
GOA
curator
ARUK-UCL
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9UJY1
determination method
IDA
biological process
regulation of cellular response to heat
determination method
TAS
1 reference
retrieved
8 April 2019
stated in
GOA
curator
Reactome
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9UJY1
determination method
TAS
biological process
determination method
ND
1 reference
retrieved
21 June 2018
stated in
GOA
curator
UniProt
UniProt protein ID
Q9UJY1
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9UJY1&geneProductId=UniProtKB:Q9UJY1
determination method
ND
protein phosphorylation
determination method
IEA
1 reference
retrieved
8 April 2019
stated in
GOA
curator
Gene Ontology Consortium
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9UJY1
determination method
IEA
Unfolded Protein Response
determination method
IMP
1 reference
retrieved
8 April 2019
stated in
HspB8 chaperone activity toward poly(Q)-containing proteins depends on its association with Bag3, a stimulator of macroautophagy.
GOA
curator
ARUK-UCL
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9UJY1
determination method
IMP
positive regulation of aggrephagy
determination method
IMP
1 reference
retrieved
8 April 2019
stated in
HspB8 chaperone activity toward poly(Q)-containing proteins depends on its association with Bag3, a stimulator of macroautophagy.
GOA
curator
ARUK-UCL
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9UJY1
determination method
IMP
has part(s)
Alpha crystallin/Hsp20 domain
1 reference
stated in
InterPro Release 71.0
reference URL
http://www.ebi.ac.uk/interpro/protein/Q9UJY1
Identifiers
RefSeq protein ID
NP_055180
1 reference
stated in
NCBI Gene
retrieved
30 May 2020
Entrez Gene ID
26353
UniProt protein ID
Q9UJY1
1 reference
stated in
UniProt
retrieved
13 November 2019
UniProt protein ID
Q9UJY1
Ensembl protein ID
ENSP00000281938
1 reference
stated in
Ensembl Release 99
Ensembl protein ID
ENSP00000281938
ENSP00000441541
1 reference
stated in
Ensembl Release 99
Ensembl protein ID
ENSP00000441541
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