(Q21115915)

Frizzled cysteine-rich domain superfamily

1 reference

Frizzled/Smoothened, transmembrane domain, protein family

1 reference

based on heuristic

inferred from protein domain or family

GPCR, family 2-like

1 reference

based on heuristic

inferred from protein domain or family

Frizzled domain, protein family

1 reference

based on heuristic

inferred from protein domain or family

1 reference

13 November 2019

1 reference

13 November 2019

protein homodimerization activity

1 reference

8 April 2019

Mutant Frizzled 4 associated with vitreoretinopathy traps wild-type Frizzled in the endoplasmic reticulum by oligomerization

GOA

curator

British Heart Foundation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O00144

signal transducer activity

IPI

1 reference

27 March 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=O00144&geneProductId=UniProtKB:O00144

1 reference

16 July 2018

Identification of WNT/beta-CATENIN signaling pathway components in human cumulus cells

http://www.ebi.ac.uk/QuickGO/annotations?protein=O00144&geneProductId=UniProtKB:O00144

protein heterodimerization activity

IPI

1 reference

8 April 2019

Mutant Frizzled 4 associated with vitreoretinopathy traps wild-type Frizzled in the endoplasmic reticulum by oligomerization

GOA

curator

British Heart Foundation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O00144

transmembrane signaling receptor activity

IPI

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O00144

Wnt-activated receptor activity

4 references

8 April 2019

A novel human homologue of the Drosophila frizzled wnt receptor gene binds wingless protein and is in the Williams syndrome deletion at 7q11.23

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O00144

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O00144

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O00144

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O00144

G protein-coupled receptor activity

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O00144

2 references

4 references

16 July 2018

A novel human homologue of the Drosophila frizzled wnt receptor gene binds wingless protein and is in the Williams syndrome deletion at 7q11.23

http://www.ebi.ac.uk/QuickGO/annotations?protein=O00144&geneProductId=UniProtKB:O00144

16 July 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=O00144&geneProductId=UniProtKB:O00144

16 July 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=O00144&geneProductId=UniProtKB:O00144

16 July 2018

Identification of WNT/beta-CATENIN signaling pathway components in human cumulus cells

http://www.ebi.ac.uk/QuickGO/annotations?protein=O00144&geneProductId=UniProtKB:O00144

1 reference

8 April 2019

Expression profile of the embryonic markers nanog, OCT-4, SSEA-1, SSEA-4, and frizzled-9 receptor in human periodontal ligament mesenchymal stem cells

GOA

curator

British Heart Foundation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O00144

perinuclear region of cytoplasm

IDA

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O00144

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O00144

endoplasmic reticulum membrane

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O00144

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O00144

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O00144

mitochondrial membranes

1 reference

8 April 2019

integral component of membrane

4 references

16 July 2018

A novel human homologue of the Drosophila frizzled wnt receptor gene binds wingless protein and is in the Williams syndrome deletion at 7q11.23

http://www.ebi.ac.uk/QuickGO/annotations?protein=O00144&geneProductId=UniProtKB:O00144

16 July 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=O00144&geneProductId=UniProtKB:O00144

16 July 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=O00144&geneProductId=UniProtKB:O00144

16 July 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=O00144&geneProductId=UniProtKB:O00144

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O00144

glutamatergic synapse

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O00144

5 references

8 April 2019

A novel human homologue of the Drosophila frizzled wnt receptor gene binds wingless protein and is in the Williams syndrome deletion at 7q11.23

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O00144

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O00144

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O00144

8 April 2019

Identification of WNT/beta-CATENIN signaling pathway components in human cumulus cells

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O00144

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O00144

integral component of membrane

3 references

8 April 2019

A novel human homologue of the Drosophila frizzled wnt receptor gene binds wingless protein and is in the Williams syndrome deletion at 7q11.23

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O00144

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O00144

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O00144

G protein-coupled receptor signaling pathway

biological process

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O00144

nervous system development

1 reference

8 April 2019

A novel human homologue of the Drosophila frizzled wnt receptor gene binds wingless protein and is in the Williams syndrome deletion at 7q11.23

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O00144

multicellular organism development

TAS

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O00144

cell surface receptor signaling pathway

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O00144

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O00144

neuroblast proliferation

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O00144

B cell differentiation

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O00144

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O00144

release of cytochrome c from mitochondria

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O00144

positive regulation of apoptotic process

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O00144

regulation of cytosolic calcium ion concentration

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O00144

negative regulation of mitochondrial depolarization

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O00144

negative regulation of necroptotic process

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O00144

negative regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O00144

positive regulation of neural precursor cell proliferation

1 reference

8 April 2019

A human neurodevelopmental model for Williams syndrome

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O00144

non-canonical Wnt signaling pathway

IMP

1 reference

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O00144

canonical Wnt signaling pathway

1 reference

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O00144

postsynapse organization

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O00144

regulation of postsynaptic cytosolic calcium ion concentration

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O00144

1 reference

GPCR, family 2-like

1 reference

Frizzled/Smoothened, transmembrane domain

1 reference