(Q21115922)

signal transducer activity

IPI

1 reference

27 March 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=O75084&geneProductId=UniProtKB:O75084

3 references

27 March 2018

Wnt signaling in midbrain dopaminergic neuron development and regenerative medicine for Parkinson's disease

Parkinsons Disease Gene Ontology Initiative

http://www.ebi.ac.uk/QuickGO/annotations?protein=O75084&geneProductId=UniProtKB:O75084

27 March 2018

Functional interaction between Wnt3 and Frizzled-7 leads to activation of the Wnt/beta-catenin signaling pathway in hepatocellular carcinoma cells

http://www.ebi.ac.uk/QuickGO/annotations?protein=O75084&geneProductId=UniProtKB:O75084

27 March 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=O75084&geneProductId=UniProtKB:O75084

6 references

1 January 2018

Frizzled 7 and PIP2 binding by syntenin PDZ2 domain supports Frizzled 7 trafficking and signalling

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O75084

1 January 2018

Functional interaction between Wnt3 and Frizzled-7 leads to activation of the Wnt/beta-catenin signaling pathway in hepatocellular carcinoma cells

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O75084

1 January 2018

Systematic protein-protein interaction mapping for clinically relevant human GPCRs

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O75084

1 January 2018

Soluble Frizzled-7 receptor inhibits Wnt signaling and sensitizes hepatocellular carcinoma cells towards doxorubicin

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O75084

1 January 2018

The postsynaptic density 95/disc-large/zona occludens protein syntenin directly interacts with frizzled 7 and supports noncanonical Wnt signaling

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O75084

1 January 2018

Towards a proteome-scale map of the human protein–protein interaction network

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O75084

transmembrane signaling receptor activity

IPI

1 reference

1 January 2018

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O75084

phosphatidylinositol-4,5-bisphosphate binding

1 reference

1 January 2018

Frizzled 7 and PIP2 binding by syntenin PDZ2 domain supports Frizzled 7 trafficking and signalling

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O75084

Wnt-activated receptor activity

5 references

1 January 2018

Wnt signaling in midbrain dopaminergic neuron development and regenerative medicine for Parkinson's disease

Parkinsons Disease Gene Ontology Initiative

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O75084

1 January 2018

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O75084

1 January 2018

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O75084

1 January 2018

Mapping of Wnt-Frizzled interactions by multiplex CRISPR targeting of receptor gene families.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O75084

1 January 2018

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O75084

G protein-coupled receptor activity

IBA

1 reference

1 January 2018

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O75084

4 references

1 January 2018

Wnt signaling in midbrain dopaminergic neuron development and regenerative medicine for Parkinson's disease

Parkinsons Disease Gene Ontology Initiative

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O75084

1 January 2018

Functional interaction between Wnt3 and Frizzled-7 leads to activation of the Wnt/beta-catenin signaling pathway in hepatocellular carcinoma cells

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O75084

1 January 2018

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O75084

1 January 2018

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O75084

integral component of membrane

IBA

cell component

3 references

2 references

6 references

27 March 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=O75084&geneProductId=UniProtKB:O75084

27 March 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=O75084&geneProductId=UniProtKB:O75084

27 March 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=O75084&geneProductId=UniProtKB:O75084

27 March 2018

Frizzled 7 and PIP2 binding by syntenin PDZ2 domain supports Frizzled 7 trafficking and signalling

http://www.ebi.ac.uk/QuickGO/annotations?protein=O75084&geneProductId=UniProtKB:O75084

27 March 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=O75084&geneProductId=UniProtKB:O75084

27 March 2018

The postsynaptic density 95/disc-large/zona occludens protein syntenin directly interacts with frizzled 7 and supports noncanonical Wnt signaling

http://www.ebi.ac.uk/QuickGO/annotations?protein=O75084&geneProductId=UniProtKB:O75084

recycling endosome membrane

1 reference

1 January 2018

Frizzled 7 and PIP2 binding by syntenin PDZ2 domain supports Frizzled 7 trafficking and signalling

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O75084

1 reference

1 January 2018

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O75084

1 reference

1 January 2018

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O75084

7 references

1 January 2018

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O75084

1 January 2018

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O75084

1 January 2018

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O75084

1 January 2018

Frizzled 7 and PIP2 binding by syntenin PDZ2 domain supports Frizzled 7 trafficking and signalling

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O75084

1 January 2018

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O75084

1 January 2018

The postsynaptic density 95/disc-large/zona occludens protein syntenin directly interacts with frizzled 7 and supports noncanonical Wnt signaling

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O75084

1 January 2018

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O75084

cellular response to retinoic acid

IBA

biological process

1 reference

1 January 2018

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O75084

G protein-coupled receptor signaling pathway

ISS

1 reference

1 January 2018

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O75084

non-canonical Wnt signaling pathway

1 reference

27 March 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=O75084&geneProductId=UniProtKB:O75084

regulation of transcription, DNA-templated

1 reference

1 January 2018

The WNT receptor FZD7 contributes to self-renewal signaling of human embryonic stem cells

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O75084

positive regulation of epithelial cell proliferation involved in wound healing

1 reference

1 January 2018

Functional interaction between Wnt3 and Frizzled-7 leads to activation of the Wnt/beta-catenin signaling pathway in hepatocellular carcinoma cells

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O75084

T cell differentiation in thymus

1 reference

1 January 2018

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O75084

non-canonical Wnt signaling pathway via JNK cascade

1 reference

1 January 2018

Down-regulation of frizzled-7 expression decreases survival, invasion and metastatic capabilities of colon cancer cells

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O75084

negative regulation of ectodermal cell fate specification

1 reference

1 January 2018

The WNT receptor FZD7 contributes to self-renewal signaling of human embryonic stem cells

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O75084

somatic stem cell division

1 reference

1 January 2018

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O75084

positive regulation of JNK cascade

1 reference

1 January 2018

The postsynaptic density 95/disc-large/zona occludens protein syntenin directly interacts with frizzled 7 and supports noncanonical Wnt signaling

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O75084

IC

Wnt signaling pathway

stem cell population maintenance

2 references

1 reference

1 January 2018

The WNT receptor FZD7 contributes to self-renewal signaling of human embryonic stem cells

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O75084

positive regulation of transcription, DNA-templated

multicellular organism development

1 reference

1 January 2018

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O75084

cell surface receptor signaling pathway

1 reference

1 January 2018

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O75084

skeletal muscle satellite cell maintenance involved in skeletal muscle regeneration

1 reference

1 January 2018

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O75084

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O75084

neuron differentiation

1 reference

1 January 2018

canonical Wnt signaling pathway

ISS

6 references

27 March 2018

Down-regulation of frizzled-7 expression decreases survival, invasion and metastatic capabilities of colon cancer cells

http://www.ebi.ac.uk/QuickGO/annotations?protein=O75084&geneProductId=UniProtKB:O75084

27 March 2018

Functional interaction between Wnt3 and Frizzled-7 leads to activation of the Wnt/beta-catenin signaling pathway in hepatocellular carcinoma cells

http://www.ebi.ac.uk/QuickGO/annotations?protein=O75084&geneProductId=UniProtKB:O75084

27 March 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=O75084&geneProductId=UniProtKB:O75084

27 March 2018

Mapping of Wnt-Frizzled interactions by multiplex CRISPR targeting of receptor gene families.

http://www.ebi.ac.uk/QuickGO/annotations?protein=O75084&geneProductId=UniProtKB:O75084

27 March 2018

Direct interaction between NHERF1 and Frizzled regulates β-catenin signaling

http://www.ebi.ac.uk/QuickGO/annotations?protein=O75084&geneProductId=UniProtKB:O75084

27 March 2018

Ror2 modulates the canonical Wnt signaling in lung epithelial cells through cooperation with Fzd2

http://www.ebi.ac.uk/QuickGO/annotations?protein=O75084&geneProductId=UniProtKB:O75084

substrate adhesion-dependent cell spreading

1 reference

1 January 2018

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O75084

positive regulation of phosphorylation

1 reference

1 January 2018

The postsynaptic density 95/disc-large/zona occludens protein syntenin directly interacts with frizzled 7 and supports noncanonical Wnt signaling

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O75084

1 reference

1 January 2018

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O75084

mesenchymal to epithelial transition

1 reference

1 January 2018

Frizzled-7 dictates three-dimensional organization of colorectal cancer cell carcinoids

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O75084

negative regulation of cardiac muscle cell differentiation

1 reference

1 January 2018

Overexpression of microRNA-1 promotes cardiomyocyte commitment from human cardiovascular progenitors via suppressing WNT and FGF signaling pathways

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O75084

regulation of canonical Wnt signaling pathway

IGI

1 reference

1 January 2018

A novel frizzled gene identified in human esophageal carcinoma mediates APC/beta-catenin signals

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O75084

canonical Wnt signaling pathway

7 references

1 January 2018

Functional interaction between Wnt3 and Frizzled-7 leads to activation of the Wnt/beta-catenin signaling pathway in hepatocellular carcinoma cells

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O75084

1 January 2018

Down-regulation of frizzled-7 expression decreases survival, invasion and metastatic capabilities of colon cancer cells

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O75084

1 January 2018

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O75084

1 January 2018

Mapping of Wnt-Frizzled interactions by multiplex CRISPR targeting of receptor gene families.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O75084

1 January 2018

Direct interaction between NHERF1 and Frizzled regulates β-catenin signaling

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O75084

1 January 2018

Ror2 modulates the canonical Wnt signaling in lung epithelial cells through cooperation with Fzd2

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O75084

1 January 2018

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O75084

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/O75084

GPCR, family 2-like

1 reference

stated in

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/O75084

Frizzled/Smoothened, transmembrane domain

1 reference

stated in

InterPro Release 71.0