(Q21115941)

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/Q13467

Frizzled cysteine-rich domain superfamily

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/Q13467

Frizzled/Smoothened, transmembrane domain, protein family

1 reference

GPCR, family 2-like

1 reference

Frizzled-5, CRD domain, protein family

1 reference

Frizzled domain, protein family

1 reference

1 reference

13 November 2019

1 reference

13 November 2019

1 reference

11 April 2017

Dysfunction of Wnt signaling and synaptic disassembly in neurodegenerative diseases

http://www.ebi.ac.uk/QuickGO/GAnnotation?protein=Q13467

signal transducer activity

http://www.ebi.ac.uk/QuickGO/GAnnotation?protein=Q13467

1 reference

11 April 2017

Wnt-protein binding

Wnt5A/CaMKII signaling contributes to the inflammatory response of macrophages and is a target for the antiinflammatory action of activated protein C and interleukin-10

5 references

11 April 2017

http://www.ebi.ac.uk/QuickGO/GAnnotation?protein=Q13467

11 April 2017

Functional characterization of WNT7A signaling in PC12 cells: interaction with A FZD5 x LRP6 receptor complex and modulation by Dickkopf proteins

http://www.ebi.ac.uk/QuickGO/GAnnotation?protein=Q13467

11 April 2017

Wnt2b controls retinal cell differentiation at the ciliary marginal zone

http://www.ebi.ac.uk/QuickGO/GAnnotation?protein=Q13467

11 April 2017

Wnt2b controls retinal cell differentiation at the ciliary marginal zone

http://www.ebi.ac.uk/QuickGO/GAnnotation?protein=Q13467

11 April 2017

http://www.ebi.ac.uk/QuickGO/GAnnotation?protein=Q13467

protein binding

3 references

11 April 2017

Tumour suppressor RNF43 is a stem-cell E3 ligase that induces endocytosis of Wnt receptors

http://www.ebi.ac.uk/QuickGO/GAnnotation?protein=Q13467

11 April 2017

A coated vesicle-associated kinase of 104 kDa (CVAK104) induces lysosomal degradation of frizzled 5 (Fzd5)

IntAct protein interaction database

http://www.ebi.ac.uk/QuickGO/GAnnotation?protein=Q13467

11 April 2017

The pseudoreceptor BMP and activin membrane-bound inhibitor positively modulates Wnt/beta-catenin signaling

http://www.ebi.ac.uk/QuickGO/GAnnotation?protein=Q13467

protein kinase binding

1 reference

11 April 2017

A coated vesicle-associated kinase of 104 kDa (CVAK104) induces lysosomal degradation of frizzled 5 (Fzd5)

http://www.ebi.ac.uk/QuickGO/GAnnotation?protein=Q13467

ubiquitin protein ligase binding

1 reference

11 April 2017

ZNRF3 promotes Wnt receptor turnover in an R-spondin-sensitive manner

http://www.ebi.ac.uk/QuickGO/GAnnotation?protein=Q13467

transmembrane signaling receptor activity

http://www.ebi.ac.uk/QuickGO/GAnnotation?protein=Q13467

1 reference

11 April 2017

Wnt-activated receptor activity

Dysfunction of Wnt signaling and synaptic disassembly in neurodegenerative diseases

3 references

11 April 2017

http://www.ebi.ac.uk/QuickGO/GAnnotation?protein=Q13467

http://www.ebi.ac.uk/QuickGO/GAnnotation?protein=Q13467

11 April 2017

11 April 2017

A member of the Frizzled protein family mediating axis induction by Wnt-5A

http://www.ebi.ac.uk/QuickGO/GAnnotation?protein=Q13467

G protein-coupled receptor activity

IC

http://www.ebi.ac.uk/QuickGO/GAnnotation?protein=Q13467

1 reference

11 April 2017

clathrin-coated endocytic vesicle membrane

cell component

http://www.ebi.ac.uk/QuickGO/GAnnotation?protein=Q13467

1 reference

11 April 2017

early endosome membrane

http://www.ebi.ac.uk/QuickGO/GAnnotation?protein=Q13467

1 reference

11 April 2017

membrane

bicellular tight junction

2 references

1 reference

11 April 2017

http://www.ebi.ac.uk/QuickGO/GAnnotation?protein=Q13467

Golgi membrane

http://www.ebi.ac.uk/QuickGO/GAnnotation?protein=Q13467

1 reference

11 April 2017

cell surface

1 reference

11 April 2017

A coated vesicle-associated kinase of 104 kDa (CVAK104) induces lysosomal degradation of frizzled 5 (Fzd5)

http://www.ebi.ac.uk/QuickGO/GAnnotation?protein=Q13467

early endosome

1 reference

11 April 2017

http://www.ebi.ac.uk/QuickGO/GAnnotation?protein=Q13467

perinuclear region of cytoplasm

1 reference

11 April 2017

http://www.ebi.ac.uk/QuickGO/GAnnotation?protein=Q13467

integral component of membrane

http://www.ebi.ac.uk/QuickGO/GAnnotation?protein=Q13467

1 reference

11 April 2017

G protein-coupled receptor signaling pathway

biological process

http://www.ebi.ac.uk/QuickGO/GAnnotation?protein=Q13467

1 reference

11 April 2017

T cell differentiation in thymus

1 reference

11 April 2017

http://www.ebi.ac.uk/QuickGO/GAnnotation?protein=Q13467

chorionic trophoblast cell differentiation

1 reference

11 April 2017

http://www.ebi.ac.uk/QuickGO/GAnnotation?protein=Q13467

positive regulation of protein targeting to mitochondrion

1 reference

11 April 2017

Genome-wide RNAi screen identifies the Parkinson disease GWAS risk locus SREBF1 as a regulator of mitophagy

http://www.ebi.ac.uk/QuickGO/GAnnotation?protein=Q13467

positive regulation of JUN kinase activity

1 reference

11 April 2017

http://www.ebi.ac.uk/QuickGO/GAnnotation?protein=Q13467

apoptotic process involved in morphogenesis

1 reference

11 April 2017

http://www.ebi.ac.uk/QuickGO/GAnnotation?protein=Q13467

regulation of chorionic trophoblast cell proliferation

1 reference

11 April 2017

http://www.ebi.ac.uk/QuickGO/GAnnotation?protein=Q13467

regulation of bicellular tight junction assembly

1 reference

11 April 2017

http://www.ebi.ac.uk/QuickGO/GAnnotation?protein=Q13467

regulation of canonical Wnt signaling pathway

1 reference

11 April 2017

http://www.ebi.ac.uk/QuickGO/GAnnotation?protein=Q13467

cellular response to molecule of bacterial origin

1 reference

11 April 2017

The Wingless homolog WNT5A and its receptor Frizzled-5 regulate inflammatory responses of human mononuclear cells induced by microbial stimulation

http://www.ebi.ac.uk/QuickGO/GAnnotation?protein=Q13467

positive regulation of interferon-gamma production

1 reference

11 April 2017

The Wingless homolog WNT5A and its receptor Frizzled-5 regulate inflammatory responses of human mononuclear cells induced by microbial stimulation

http://www.ebi.ac.uk/QuickGO/GAnnotation?protein=Q13467

embryonic axis specification

1 reference

11 April 2017

A novel set of Wnt-Frizzled fusion proteins identifies receptor components that activate beta -catenin-dependent signaling

http://www.ebi.ac.uk/QuickGO/GAnnotation?protein=Q13467

labyrinthine layer blood vessel development

1 reference

11 April 2017

http://www.ebi.ac.uk/QuickGO/GAnnotation?protein=Q13467

cell maturation

1 reference

11 April 2017

http://www.ebi.ac.uk/QuickGO/GAnnotation?protein=Q13467

embryonic camera-type eye development

1 reference

11 April 2017

http://www.ebi.ac.uk/QuickGO/GAnnotation?protein=Q13467

multicellular organism development

http://www.ebi.ac.uk/QuickGO/GAnnotation?protein=Q13467

1 reference

11 April 2017

cell surface receptor signaling pathway

http://www.ebi.ac.uk/QuickGO/GAnnotation?protein=Q13467

1 reference

11 April 2017

vasculature development

1 reference

11 April 2017

http://www.ebi.ac.uk/QuickGO/GAnnotation?protein=Q13467

regulation of autophagy of mitochondrion

1 reference

11 April 2017

Genome-wide RNAi screen identifies the Parkinson disease GWAS risk locus SREBF1 as a regulator of mitophagy

http://www.ebi.ac.uk/QuickGO/GAnnotation?protein=Q13467

branching involved in labyrinthine layer morphogenesis

1 reference

11 April 2017

http://www.ebi.ac.uk/QuickGO/GAnnotation?protein=Q13467

embryonic camera-type eye morphogenesis

1 reference

11 April 2017

http://www.ebi.ac.uk/QuickGO/GAnnotation?protein=Q13467

post-embryonic camera-type eye development

1 reference

11 April 2017

http://www.ebi.ac.uk/QuickGO/GAnnotation?protein=Q13467

positive regulation of T cell cytokine production

1 reference

11 April 2017

The Wingless homolog WNT5A and its receptor Frizzled-5 regulate inflammatory responses of human mononuclear cells induced by microbial stimulation

Community Assessment of Community Annotation with Ontologies

http://www.ebi.ac.uk/QuickGO/GAnnotation?protein=Q13467

angiogenesis

1 reference

11 April 2017

http://www.ebi.ac.uk/QuickGO/GAnnotation?protein=Q13467

neuron differentiation

http://www.ebi.ac.uk/QuickGO/GAnnotation?protein=Q13467

1 reference

11 April 2017

Wnt signaling pathway involved in dorsal/ventral axis specification

ISS

1 reference

11 April 2017

http://www.ebi.ac.uk/QuickGO/GAnnotation?protein=Q13467

canonical Wnt signaling pathway

A member of the Frizzled protein family mediating axis induction by Wnt-5A

5 references

11 April 2017

http://www.ebi.ac.uk/QuickGO/GAnnotation?protein=Q13467

11 April 2017

http://www.ebi.ac.uk/QuickGO/GAnnotation?protein=Q13467

11 April 2017

Secreted Frizzled-related protein potentiation versus inhibition of Wnt3a/β-catenin signaling

http://www.ebi.ac.uk/QuickGO/GAnnotation?protein=Q13467

11 April 2017

Functional characterization of WNT7A signaling in PC12 cells: interaction with A FZD5 x LRP6 receptor complex and modulation by Dickkopf proteins

http://www.ebi.ac.uk/QuickGO/GAnnotation?protein=Q13467

11 April 2017

A novel set of Wnt-Frizzled fusion proteins identifies receptor components that activate beta -catenin-dependent signaling

http://www.ebi.ac.uk/QuickGO/GAnnotation?protein=Q13467

synapse assembly

1 reference

11 April 2017

Dysfunction of Wnt signaling and synaptic disassembly in neurodegenerative diseases

http://www.ebi.ac.uk/QuickGO/GAnnotation?protein=Q13467

syncytiotrophoblast cell differentiation involved in labyrinthine layer development

1 reference

11 April 2017

http://www.ebi.ac.uk/QuickGO/GAnnotation?protein=Q13467

anterior/posterior axis specification, embryo

1 reference

11 April 2017

A member of the Frizzled protein family mediating axis induction by Wnt-5A

http://www.ebi.ac.uk/QuickGO/GAnnotation?protein=Q13467

Spemann organizer formation

1 reference

11 April 2017

A member of the Frizzled protein family mediating axis induction by Wnt-5A

http://www.ebi.ac.uk/QuickGO/GAnnotation?protein=Q13467

positive regulation of transcription by RNA polymerase II

Interaction of Frizzled 7 and Dishevelled in Xenopus

3 references

11 April 2017

http://www.ebi.ac.uk/QuickGO/GAnnotation?protein=Q13467

11 April 2017

http://www.ebi.ac.uk/QuickGO/GAnnotation?protein=Q13467

11 April 2017

Functional characterization of WNT7A signaling in PC12 cells: interaction with A FZD5 x LRP6 receptor complex and modulation by Dickkopf proteins

http://www.ebi.ac.uk/QuickGO/GAnnotation?protein=Q13467

negative regulation of cell population proliferation

1 reference

11 April 2017

http://www.ebi.ac.uk/QuickGO/GAnnotation?protein=Q13467

signal transduction

http://www.ebi.ac.uk/QuickGO/GAnnotation?protein=Q13467

1 reference

11 April 2017

Wnt signaling pathway, calcium modulating pathway

http://www.ebi.ac.uk/QuickGO/GAnnotation?protein=Q13467

1 reference

11 April 2017

Wnt signaling pathway, planar cell polarity pathway

http://www.ebi.ac.uk/QuickGO/GAnnotation?protein=Q13467

1 reference

11 April 2017

beta-catenin destruction complex disassembly

http://www.ebi.ac.uk/QuickGO/GAnnotation?protein=Q13467

1 reference

11 April 2017