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(Q21116353)
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AF4/FMR2 family member 3
mammalian protein found in Homo sapiens
MLLT2-related protein
lymphoid nuclear protein related to AF4
lymphoid nuclear protein 4
protein LAF-4
AFF3
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edit
Statements
instance of
protein
1 reference
stated in
UniProt
retrieved
5 December 2018
UniProt protein ID
P51826
part of
Transcription factor AF4/FMR2
1 reference
stated in
InterPro Release 71.0
reference URL
http://www.ebi.ac.uk/interpro/protein/P51826
found in taxon
Homo sapiens
1 reference
stated in
UniProt
retrieved
5 December 2018
UniProt protein ID
P51826
encoded by
AFF3
1 reference
stated in
UniProt
retrieved
5 December 2018
UniProt protein ID
P51826
molecular function
DNA binding
determination method
IEA
1 reference
retrieved
8 April 2019
stated in
GOA
curator
UniProt
UniProt protein ID
P51826
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P51826
determination method
IEA
double-stranded DNA binding
determination method
IDA
1 reference
retrieved
27 March 2018
stated in
LAF-4 encodes a lymphoid nuclear protein with transactivation potential that is homologous to AF-4, the gene fused to MLL in t(4;11) leukemias
GOA
curator
British Heart Foundation
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P51826&geneProductId=UniProtKB:P51826
determination method
IDA
double-stranded DNA binding
determination method
IBA
IDA
2 references
retrieved
8 April 2019
stated in
LAF-4 encodes a lymphoid nuclear protein with transactivation potential that is homologous to AF-4, the gene fused to MLL in t(4;11) leukemias
GOA
curator
British Heart Foundation
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P51826
determination method
IDA
retrieved
8 April 2019
stated in
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
GOA
curator
GO Central
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P51826
determination method
IBA
DNA-binding transcription factor activity
determination method
IBA
1 reference
retrieved
8 April 2019
stated in
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
GOA
curator
GO Central
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P51826
determination method
IBA
cell component
nucleus
determination method
IDA
IEA
2 references
retrieved
27 March 2018
stated in
GOA
curator
UniProt
UniProt protein ID
P51826
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P51826&geneProductId=UniProtKB:P51826
determination method
IEA
retrieved
27 March 2018
stated in
LAF-4 encodes a lymphoid nuclear protein with transactivation potential that is homologous to AF-4, the gene fused to MLL in t(4;11) leukemias
GOA
curator
British Heart Foundation
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P51826&geneProductId=UniProtKB:P51826
determination method
IDA
nucleoplasm
determination method
IDA
1 reference
retrieved
8 April 2019
stated in
GOA
curator
Human Protein Atlas
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P51826
determination method
IDA
cytosol
determination method
IDA
1 reference
retrieved
8 April 2019
stated in
GOA
curator
Human Protein Atlas
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P51826
determination method
IDA
nuclear body
determination method
IDA
1 reference
retrieved
8 April 2019
stated in
GOA
curator
Human Protein Atlas
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P51826
determination method
IDA
nucleus
determination method
IBA
IDA
IEA
3 references
retrieved
8 April 2019
stated in
GOA
curator
UniProt
UniProt protein ID
P51826
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P51826
determination method
IEA
retrieved
8 April 2019
stated in
LAF-4 encodes a lymphoid nuclear protein with transactivation potential that is homologous to AF-4, the gene fused to MLL in t(4;11) leukemias
GOA
curator
British Heart Foundation
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P51826
determination method
IDA
retrieved
8 April 2019
stated in
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
GOA
curator
GO Central
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P51826
determination method
IBA
transcription elongation factor complex
determination method
IBA
1 reference
retrieved
8 April 2019
stated in
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
GOA
curator
GO Central
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P51826
determination method
IBA
super elongation complex
determination method
IBA
1 reference
retrieved
8 April 2019
stated in
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
GOA
curator
GO Central
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P51826
determination method
IBA
biological process
response to tumor necrosis factor
determination method
IMP
1 reference
retrieved
8 April 2019
stated in
Investigation of rheumatoid arthritis susceptibility genes identifies association of AFF3 and CD226 variants with response to anti-tumour necrosis factor treatment
GOA
curator
British Heart Foundation
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P51826
determination method
IMP
regulation of transcription, DNA-templated
determination method
IEA
1 reference
retrieved
8 April 2019
stated in
GOA
curator
Gene Ontology Consortium
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P51826
determination method
IEA
transcription, DNA-templated
determination method
IEA
1 reference
retrieved
27 March 2018
stated in
GOA
curator
UniProt
UniProt protein ID
P51826
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P51826&geneProductId=UniProtKB:P51826
determination method
IEA
embryonic hindlimb morphogenesis
determination method
IMP
1 reference
retrieved
8 April 2019
stated in
Triangular tibia with fibular aplasia associated with a microdeletion on 2q11.2 encompassing LAF4
GOA
curator
British Heart Foundation
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P51826
determination method
IMP
Identifiers
RefSeq protein ID
NP_001020279
1 reference
stated in
NCBI Gene
retrieved
7 December 2018
Entrez Gene ID
3899
NP_002276
1 reference
stated in
NCBI Gene
retrieved
7 December 2018
Entrez Gene ID
3899
XP_005264000
1 reference
stated in
NCBI Gene
retrieved
7 December 2018
Entrez Gene ID
3899
XP_005264002
1 reference
stated in
NCBI Gene
retrieved
7 December 2018
Entrez Gene ID
3899
XP_011509471
1 reference
stated in
NCBI Gene
retrieved
7 December 2018
Entrez Gene ID
3899
XP_011509472
1 reference
stated in
NCBI Gene
retrieved
7 December 2018
Entrez Gene ID
3899
XP_011509473
1 reference
stated in
NCBI Gene
retrieved
7 December 2018
Entrez Gene ID
3899
XP_011509475
1 reference
stated in
NCBI Gene
retrieved
7 December 2018
Entrez Gene ID
3899
XP_011509476
1 reference
stated in
NCBI Gene
retrieved
7 December 2018
Entrez Gene ID
3899
XP_011509477
1 reference
stated in
NCBI Gene
retrieved
7 December 2018
Entrez Gene ID
3899
XP_011509478
1 reference
stated in
NCBI Gene
retrieved
7 December 2018
Entrez Gene ID
3899
XP_011509479
1 reference
stated in
NCBI Gene
retrieved
7 December 2018
Entrez Gene ID
3899
XP_011509480
1 reference
stated in
NCBI Gene
retrieved
7 December 2018
Entrez Gene ID
3899
XP_011509481
1 reference
stated in
NCBI Gene
retrieved
7 December 2018
Entrez Gene ID
3899
XP_016859574
1 reference
stated in
NCBI Gene
retrieved
7 December 2018
Entrez Gene ID
3899
XP_016859575
1 reference
stated in
NCBI Gene
retrieved
7 December 2018
Entrez Gene ID
3899
XP_016859576
1 reference
stated in
NCBI Gene
retrieved
7 December 2018
Entrez Gene ID
3899
XP_024308651
1 reference
stated in
NCBI Gene
retrieved
7 December 2018
Entrez Gene ID
3899
UniProt protein ID
P51826
1 reference
stated in
UniProt
retrieved
5 December 2018
UniProt protein ID
P51826
Ensembl protein ID
ENSP00000317421
1 reference
stated in
ensembl Release 96
Ensembl protein ID
ENSP00000317421
ENSP00000386834
1 reference
stated in
ensembl Release 96
Ensembl protein ID
ENSP00000386834
ENSP00000387207
1 reference
stated in
ensembl Release 96
Ensembl protein ID
ENSP00000387207
ENSP00000393732
1 reference
stated in
ensembl Release 96
Ensembl protein ID
ENSP00000393732
ENSP00000395068
1 reference
stated in
ensembl Release 96
Ensembl protein ID
ENSP00000395068
ENSP00000396582
1 reference
stated in
ensembl Release 96
Ensembl protein ID
ENSP00000396582
ENSP00000399795
1 reference
stated in
ensembl Release 96
Ensembl protein ID
ENSP00000399795
ENSP00000406484
1 reference
stated in
ensembl Release 96
Ensembl protein ID
ENSP00000406484
ENSP00000407448
1 reference
stated in
ensembl Release 96
Ensembl protein ID
ENSP00000407448
ENSP00000411383
1 reference
stated in
ensembl Release 96
Ensembl protein ID
ENSP00000411383
ENSP00000414099
1 reference
stated in
ensembl Release 96
Ensembl protein ID
ENSP00000414099
ENSP00000416131
1 reference
stated in
ensembl Release 96
Ensembl protein ID
ENSP00000416131
ENSP00000416685
1 reference
stated in
ensembl Release 96
Ensembl protein ID
ENSP00000416685
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