(Q21116844)

http://www.ebi.ac.uk/interpro/protein/Q9Y2D1

Basic-leucine zipper domain, protein family

1 reference

based on heuristic

inferred from protein domain or family

1 reference

13 November 2019

1 reference

13 November 2019

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Y2D1

RNA polymerase II transcription regulatory region sequence-specific DNA binding

1 reference

27 March 2018

The bZIP transcription factor ATFx binds human T-cell leukemia virus type 1 (HTLV-1) Tax and represses HTLV-1 long terminal repeat-mediated transcription

Norwegian University of Science and Technology, Systems Biology team

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9Y2D1&geneProductId=UniProtKB:Q9Y2D1

transcription corepressor activity

IMP

1 reference

8 April 2019

Human Cdc34 and Rad6B ubiquitin-conjugating enzymes target repressors of cyclic AMP-induced transcription for proteolysis

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Y2D1

DNA-binding transcription factor activity

TAS

3 references

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Y2D1

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Y2D1

8 April 2019

Regulation of the human CHOP gene promoter by the stress response transcription factor ATF5 via the AARE1 site in human hepatoma HepG2 cells

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Y2D1

DNA-binding transcription activator activity, RNA polymerase II-specific

1 reference

8 April 2019

Norwegian University of Science and Technology, Systems Biology team

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Y2D1

1 reference

8 April 2019

ATF5 Connects the Pericentriolar Materials to the Proximal End of the Mother Centriole

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Y2D1

1 reference

8 April 2019

Stabilization of ATF5 by TAK1-Nemo-like kinase critically regulates the interleukin-1β-stimulated C/EBP signaling pathway

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Y2D1

5 references

8 April 2019

Human Cdc34 and Rad6B ubiquitin-conjugating enzymes target repressors of cyclic AMP-induced transcription for proteolysis

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Y2D1

8 April 2019

ATF5 Connects the Pericentriolar Materials to the Proximal End of the Mother Centriole

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Y2D1

8 April 2019

Nucleophosmin (NPM1/B23) interacts with activating transcription factor 5 (ATF5) protein and promotes proteasome- and caspase-dependent ATF5 degradation in hepatocellular carcinoma cells

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Y2D1

8 April 2019

DISC1 (Disrupted-In-Schizophrenia 1) is a centrosome-associated protein that interacts with MAP1A, MIPT3, ATF4/5 and NUDEL: regulation and loss of interaction with mutation

IntAct protein interaction database

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Y2D1

8 April 2019

Identification of bZIP interaction partners of viral proteins HBZ, MEQ, BZLF1, and K-bZIP using coiled-coil arrays

IntAct protein interaction database

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Y2D1

DNA-binding transcription factor activity, RNA polymerase II-specific

IPI

3 references

27 March 2018

A census of human transcription factors: function, expression and evolution

Norwegian University of Science and Technology, Systems Biology team

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9Y2D1&geneProductId=UniProtKB:Q9Y2D1

27 March 2018

A census of human transcription factors: function, expression and evolution

Norwegian University of Science and Technology, Systems Biology team

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9Y2D1&geneProductId=UniProtKB:Q9Y2D1

27 March 2018

Norwegian University of Science and Technology, Systems Biology team

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9Y2D1&geneProductId=UniProtKB:Q9Y2D1

RNA polymerase II transcription regulatory region sequence-specific DNA binding

ISA

DNA-binding transcription factor activity, RNA polymerase II-specific

IBA

IMP

4 references

8 April 2019

A census of human transcription factors: function, expression and evolution

Norwegian University of Science and Technology, Systems Biology team

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Y2D1

8 April 2019

A census of human transcription factors: function, expression and evolution

Norwegian University of Science and Technology, Systems Biology team

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Y2D1

8 April 2019

Norwegian University of Science and Technology, Systems Biology team

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Y2D1

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Y2D1

1 reference

8 April 2019

ATF5 Connects the Pericentriolar Materials to the Proximal End of the Mother Centriole

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Y2D1

transcription regulator complex

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Y2D1

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Y2D1

microtubule organizing center

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Y2D1

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Y2D1

3 references

27 March 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9Y2D1&geneProductId=UniProtKB:Q9Y2D1

27 March 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9Y2D1&geneProductId=UniProtKB:Q9Y2D1

27 March 2018

Nucleophosmin (NPM1/B23) interacts with activating transcription factor 5 (ATF5) protein and promotes proteasome- and caspase-dependent ATF5 degradation in hepatocellular carcinoma cells

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9Y2D1&geneProductId=UniProtKB:Q9Y2D1

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Y2D1

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Y2D1

4 references

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Y2D1

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Y2D1

8 April 2019

Nucleophosmin (NPM1/B23) interacts with activating transcription factor 5 (ATF5) protein and promotes proteasome- and caspase-dependent ATF5 degradation in hepatocellular carcinoma cells

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Y2D1

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Y2D1

negative regulation of cell cycle G2/M phase transition

IBA

biological process

1 reference

8 April 2019

Nucleophosmin (NPM1/B23) interacts with activating transcription factor 5 (ATF5) protein and promotes proteasome- and caspase-dependent ATF5 degradation in hepatocellular carcinoma cells

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Y2D1

olfactory bulb interneuron differentiation

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Y2D1

multicellular organism growth

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Y2D1

regulation of transcription by RNA polymerase II

3 references

27 March 2018

Human Cdc34 and Rad6B ubiquitin-conjugating enzymes target repressors of cyclic AMP-induced transcription for proteolysis

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9Y2D1&geneProductId=UniProtKB:Q9Y2D1

27 March 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9Y2D1&geneProductId=UniProtKB:Q9Y2D1

27 March 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9Y2D1&geneProductId=UniProtKB:Q9Y2D1

post-embryonic development

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Y2D1

transcription, DNA-templated

1 reference

27 March 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9Y2D1&geneProductId=UniProtKB:Q9Y2D1

positive regulation of transcription, DNA-templated

3 references

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Y2D1

8 April 2019

BCL-2 is a downstream target of ATF5 that mediates the prosurvival function of ATF5 in a cell type-dependent manner

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Y2D1

8 April 2019

Stabilization of ATF5 by TAK1-Nemo-like kinase critically regulates the interleukin-1β-stimulated C/EBP signaling pathway

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Y2D1

regulation of centrosome cycle

1 reference

8 April 2019

ATF5 Connects the Pericentriolar Materials to the Proximal End of the Mother Centriole

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Y2D1

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Y2D1

olfactory bulb interneuron development

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Y2D1

regulation of gene expression

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Y2D1

olfactory lobe development

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Y2D1

negative regulation of transcription, DNA-templated

1 reference

8 April 2019

Nucleophosmin (NPM1/B23) interacts with activating transcription factor 5 (ATF5) protein and promotes proteasome- and caspase-dependent ATF5 degradation in hepatocellular carcinoma cells

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Y2D1

positive regulation of transcription by RNA polymerase II

1 reference

8 April 2019

ATF5 increases cisplatin-induced apoptosis through up-regulation of cyclin D3 transcription in HeLa cells

Norwegian University of Science and Technology, Systems Biology team

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Y2D1

negative regulation of cell population proliferation

1 reference

8 April 2019

Nucleophosmin (NPM1/B23) interacts with activating transcription factor 5 (ATF5) protein and promotes proteasome- and caspase-dependent ATF5 degradation in hepatocellular carcinoma cells

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Y2D1

transcription by RNA polymerase II

1 reference

27 March 2018

Gene Ontology Consortium

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9Y2D1&geneProductId=UniProtKB:Q9Y2D1

regulation of transcription by RNA polymerase II

4 references

8 April 2019

Human Cdc34 and Rad6B ubiquitin-conjugating enzymes target repressors of cyclic AMP-induced transcription for proteolysis

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Y2D1

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Y2D1

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Y2D1

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Y2D1

Basic-leucine zipper domain

IBA

has part(s)

1 reference

stated in

InterPro Release 71.0