(Q21117074)

http://www.ebi.ac.uk/interpro/protein/Q9BUL8

1 reference

13 November 2019

1 reference

13 November 2019

protein homodimerization activity

protein N-terminus binding

IPI

1 reference

8 April 2019

Crystal structure of CCM3, a cerebral cavernous malformation protein critical for vascular integrity

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9BUL8

17 references

8 April 2019

CCM3/PDCD10 heterodimerizes with germinal center kinase III (GCKIII) proteins using a mechanism analogous to CCM3 homodimerization

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9BUL8

8 April 2019

Crystal structure of CCM3, a cerebral cavernous malformation protein critical for vascular integrity

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9BUL8

8 April 2019

Structural mechanism of CCM3 heterodimerization with GCKIII kinases

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9BUL8

8 April 2019

RHO binding to FAM65A regulates Golgi reorientation during cell migration

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9BUL8

8 April 2019

CCM3/PDCD10 stabilizes GCKIII proteins to promote Golgi assembly and cell orientation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9BUL8

8 April 2019

PDCD10 interacts with Ste20-related kinase MST4 to promote cell growth and transformation via modulation of the ERK pathway

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9BUL8

8 April 2019

A PP2A phosphatase high density interaction network identifies a novel striatin-interacting phosphatase and kinase complex linked to the cerebral cavernous malformation 3 (CCM3) protein

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9BUL8

8 April 2019

Structural basis for the unique heterodimeric assembly between cerebral cavernous malformation 3 and germinal center kinase III

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9BUL8

8 April 2019

A human interactome in three quantitative dimensions organized by stoichiometries and abundances

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9BUL8

8 April 2019

Next-generation sequencing to generate interactome datasets

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9BUL8

8 April 2019

Towards a proteome-scale map of the human protein–protein interaction network

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9BUL8

8 April 2019

A proteome-scale map of the human interactome network

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9BUL8

8 April 2019

Structural mechanism of CCM3 heterodimerization with GCKIII kinases

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9BUL8

8 April 2019

Interaction proteome of human Hippo signaling: modular control of the co-activator YAP1

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9BUL8

8 April 2019

Interlaboratory reproducibility of large-scale human protein-complex analysis by standardized AP-MS

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9BUL8

8 April 2019

Structural studies of cerebral cavernous malformations 2 (CCM2) reveal a folded helical domain at its C-terminus

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9BUL8

8 April 2019

CCM3 interacts with CCM2 indicating common pathogenesis for cerebral cavernous malformations

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9BUL8

4 references

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9BUL8

8 April 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9BUL8

8 April 2019

PDCD10 interacts with STK25 to accelerate cell apoptosis under oxidative stress

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9BUL8

8 April 2019

CCM3/PDCD10 stabilizes GCKIII proteins to promote Golgi assembly and cell orientation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9BUL8

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9BUL8

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9BUL8

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9BUL8

Large-scale proteomics and phosphoproteomics of urinary exosomes

extracellular exosome

4 references

17 October 2017

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9BUL8&geneProductId=UniProtKB:Q9BUL8

17 October 2017

MHC class II-associated proteins in B-cell exosomes and potential functional implications for exosome biogenesis

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9BUL8&geneProductId=UniProtKB:Q9BUL8

17 October 2017

In-depth proteomic analyses of exosomes isolated from expressed prostatic secretions in urine

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9BUL8&geneProductId=UniProtKB:Q9BUL8

17 October 2017

Proteomic analysis of podocyte exosome-enriched fraction from normal human urine

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9BUL8&geneProductId=UniProtKB:Q9BUL8

MHC class II-associated proteins in B-cell exosomes and potential functional implications for exosome biogenesis

extracellular exosome

3 references

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9BUL8

8 April 2019

Large-scale proteomics and phosphoproteomics of urinary exosomes

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9BUL8

8 April 2019

In-depth proteomic analyses of exosomes isolated from expressed prostatic secretions in urine

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9BUL8

intrinsic apoptotic signaling pathway in response to hydrogen peroxide

HDA

biological process

1 reference

8 April 2019

PDCD10 interacts with STK25 to accelerate cell apoptosis under oxidative stress

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9BUL8

positive regulation of MAP kinase activity

IGI

1 reference

8 April 2019

PDCD10 interacts with Ste20-related kinase MST4 to promote cell growth and transformation via modulation of the ERK pathway

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9BUL8

negative regulation of apoptotic process

1 reference

8 April 2019

PDCD10 interacts with Ste20-related kinase MST4 to promote cell growth and transformation via modulation of the ERK pathway

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9BUL8

negative regulation of gene expression

1 reference

8 April 2019

Loss of CCM3 impairs DLL4-Notch signalling: implication in endothelial angiogenesis and in inherited cerebral cavernous malformations

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9BUL8

establishment of Golgi localization

1 reference

8 April 2019

CCM3/PDCD10 stabilizes GCKIII proteins to promote Golgi assembly and cell orientation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9BUL8

CCM3/PDCD10 stabilizes GCKIII proteins to promote Golgi assembly and cell orientation

stress fiber assembly

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9BUL8

positive regulation of peptidyl-serine phosphorylation

1 reference

8 April 2019

CCM3/PDCD10 stabilizes GCKIII proteins to promote Golgi assembly and cell orientation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9BUL8

positive regulation of protein serine/threonine kinase activity

1 reference

8 April 2019

CCM3/PDCD10 stabilizes GCKIII proteins to promote Golgi assembly and cell orientation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9BUL8

1 reference

8 April 2019

CCM3/PDCD10 stabilizes GCKIII proteins to promote Golgi assembly and cell orientation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9BUL8

negative regulation of cell migration involved in sprouting angiogenesis

1 reference

8 April 2019

Loss of CCM3 impairs DLL4-Notch signalling: implication in endothelial angiogenesis and in inherited cerebral cavernous malformations

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9BUL8

positive regulation of gene expression

1 reference

8 April 2019

Loss of CCM3 impairs DLL4-Notch signalling: implication in endothelial angiogenesis and in inherited cerebral cavernous malformations

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9BUL8

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9BUL8

positive regulation of cell population proliferation

negative regulation of blood vessel endothelial cell proliferation involved in sprouting angiogenesis

1 reference

8 April 2019

Loss of CCM3 impairs DLL4-Notch signalling: implication in endothelial angiogenesis and in inherited cerebral cavernous malformations

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9BUL8

regulation of Rho protein signal transduction

1 reference

8 April 2019

CCM3/PDCD10 stabilizes GCKIII proteins to promote Golgi assembly and cell orientation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9BUL8

response to hydrogen peroxide

1 reference

8 April 2019

Adaptor protein cerebral cavernous malformation 3 (CCM3) mediates phosphorylation of the cytoskeletal proteins ezrin/radixin/moesin by mammalian Ste20-4 to protect cells from oxidative stress

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9BUL8

wound healing, spreading of cells

1 reference

8 April 2019

CCM3/PDCD10 stabilizes GCKIII proteins to promote Golgi assembly and cell orientation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9BUL8

positive regulation of Notch signaling pathway

1 reference

8 April 2019

Loss of CCM3 impairs DLL4-Notch signalling: implication in endothelial angiogenesis and in inherited cerebral cavernous malformations

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9BUL8

positive regulation of stress-activated MAPK cascade

1 reference

8 April 2019

PDCD10 interacts with STK25 to accelerate cell apoptosis under oxidative stress

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9BUL8

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9BUL8

positive regulation of intracellular protein transport

1 reference

8 April 2019

RHO binding to FAM65A regulates Golgi reorientation during cell migration

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9BUL8

cellular response to leukemia inhibitory factor

1 reference

8 April 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9BUL8

Identifiers

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

13 November 2019

1 reference

1 reference

1 reference

1 reference

1 reference

1 reference

1 reference

1 reference

1 reference

1 reference

1 reference

1 reference

1 reference

1 reference

1 reference

20 March 2016

1 reference

20 March 2016

1 reference

20 March 2016

1 reference

20 March 2016

1 reference

20 March 2016

1 reference

20 March 2016

1 reference

20 March 2016

1 reference

20 March 2016

1 reference

20 March 2016

1 reference

20 March 2016