Wikidata

(Q21117111)

English

Centrosomal protein 290

mammalian protein found in Homo sapiens

  • CT87
  • centrosomal protein 290kDa
  • centrosomal protein of 290 kDa
  • Meckel syndrome, type 4
  • Bardet-Biedl syndrome 14 protein
  • prostate cancer antigen T21
  • tumor antigen se2-2
  • cancer/testis antigen 87
  • monoclonal antibody 3H11 antigen
  • nephrocytsin-6
  • Nephrocystin-6
  • POC3 centriolar protein homolog
  • CEP290
  • CTCL tumor antigen se2-2
In more languages

Statements

molecular function
protein binding
determination method
IPI
22 references
retrieved
8 April 2019
stated in
The centriolar satellite protein CCDC66 interacts with CEP290 and functions in cilium formation and trafficking.
GOA
curator
UniProt
UniProt protein ID
O15078
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O15078
determination method
IPI
retrieved
8 April 2019
stated in
CEP162 is an axoneme-recognition protein promoting ciliary transition zone assembly at the cilia base
GOA
curator
UniProt
UniProt protein ID
O15078
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O15078
determination method
IPI
retrieved
8 April 2019
stated in
The centriolar satellite protein AZI1 interacts with BBS4 and regulates ciliary trafficking of the BBSome
GOA
curator
UniProt
UniProt protein ID
O15078
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O15078
determination method
IPI
retrieved
8 April 2019
stated in
The centriolar satellite protein Cep131 is important for genome stability
GOA
curator
UniProt
UniProt protein ID
O15078
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O15078
determination method
IPI
retrieved
8 April 2019
stated in
Exome capture reveals ZNF423 and CEP164 mutations, linking renal ciliopathies to DNA damage response signaling
GOA
curator
UniProt
UniProt protein ID
O15078
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O15078
determination method
IPI
retrieved
8 April 2019
stated in
Mapping the NPHP-JBTS-MKS protein network reveals ciliopathy disease genes and pathways
GOA
curator
UniProt
UniProt protein ID
O15078
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O15078
determination method
IPI
retrieved
8 April 2019
stated in
Ccdc13 is a novel human centriolar satellite protein required for ciliogenesis and genome stability
GOA
curator
Syscilia
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O15078
determination method
IPI
retrieved
8 April 2019
stated in
CP110 suppresses primary cilia formation through its interaction with CEP290, a protein deficient in human ciliary disease
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O15078
determination method
IPI
retrieved
8 April 2019
stated in
Genetic and physical interaction between the NPHP5 and NPHP6 gene products
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O15078
determination method
IPI
retrieved
8 April 2019
stated in
Ccdc13 is a novel human centriolar satellite protein required for ciliogenesis and genome stability
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O15078
determination method
IPI
retrieved
8 April 2019
stated in
Centriolar kinesin Kif24 interacts with CP110 to remodel microtubules and regulate ciliogenesis
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O15078
determination method
IPI
retrieved
8 April 2019
stated in
CEP162 is an axoneme-recognition protein promoting ciliary transition zone assembly at the cilia base
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O15078
determination method
IPI
retrieved
8 April 2019
stated in
Pathogenic NPHP5 mutations impair protein interaction with Cep290, a prerequisite for ciliogenesis
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O15078
determination method
IPI
retrieved
8 April 2019
stated in
Neurl4, a novel daughter centriole protein, prevents formation of ectopic microtubule organizing centres
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O15078
determination method
IPI
retrieved
8 April 2019
stated in
CEP290 interacts with the centriolar satellite component PCM-1 and is required for Rab8 localization to the primary cilium
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O15078
determination method
IPI
retrieved
8 April 2019
stated in
Exome capture reveals ZNF423 and CEP164 mutations, linking renal ciliopathies to DNA damage response signaling
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O15078
determination method
IPI
retrieved
8 April 2019
stated in
Nephrocystin proteins NPHP5 and Cep290 regulate BBSome integrity, ciliary trafficking and cargo delivery
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O15078
determination method
IPI
retrieved
8 April 2019
stated in
Mapping the NPHP-JBTS-MKS protein network reveals ciliopathy disease genes and pathways
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O15078
determination method
IPI
retrieved
8 April 2019
stated in
A Dynamic Protein Interaction Landscape of the Human Centrosome-Cilium Interface
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O15078
determination method
IPI
retrieved
8 April 2019
stated in
The centrosomal protein nephrocystin-6 is mutated in Joubert syndrome and activates transcription factor ATF4
GOA
curator
HUGO Gene Nomenclature Committee
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O15078
determination method
IPI
retrieved
8 April 2019
stated in
BBS mutations modify phenotypic expression of CEP290-related ciliopathies
GOA
curator
GO Central
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O15078
determination method
IPI
retrieved
8 April 2019
stated in
Combining Cep290 and Mkks ciliopathy alleles in mice rescues sensory defects and restores ciliogenesis
GOA
curator
GO Central
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O15078
determination method
IPI
cell component
centrosome
determination method
IDA
IEA
7 references
retrieved
8 April 2019
stated in
GOA
curator
InterPro
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O15078
determination method
IEA
retrieved
8 April 2019
stated in
Proteomic characterization of the human centrosome by protein correlation profiling
GOA
curator
UniProt
UniProt protein ID
O15078
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O15078
determination method
IDA
retrieved
8 April 2019
stated in
Novel asymmetrically localizing components of human centrosomes identified by complementary proteomics methods
GOA
curator
UniProt
UniProt protein ID
O15078
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O15078
determination method
IDA
retrieved
8 April 2019
stated in
The centriolar satellite protein AZI1 interacts with BBS4 and regulates ciliary trafficking of the BBSome
GOA
curator
UniProt
UniProt protein ID
O15078
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O15078
determination method
IDA
retrieved
8 April 2019
stated in
Casein kinase 1δ functions at the centrosome and Golgi to promote ciliogenesis
GOA
curator
Syscilia
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O15078
determination method
IDA
retrieved
8 April 2019
stated in
GOA
curator
Human Protein Atlas
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O15078
determination method
IDA
retrieved
8 April 2019
stated in
The centrosomal protein nephrocystin-6 is mutated in Joubert syndrome and activates transcription factor ATF4
GOA
curator
HUGO Gene Nomenclature Committee
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O15078
determination method
IDA
biological process

Identifiers

 
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