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Chymotrypsin like elastase 2A
mammalian protein found in Homo sapiens
elastase 2A
chymotrypsin-like elastase family member 2A
CELA2A
pancreatic elastase 2
chymotrypsin like elastase family member 2A
Elastase-2A
pancreatic elastase IIA
In more languages
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Statements
instance of
protein
1 reference
stated in
UniProt
retrieved
13 November 2019
UniProt protein ID
P08217
part of
peptidase S1A, chymotrypsin family
1 reference
stated in
InterPro Release 71.0
reference URL
http://www.ebi.ac.uk/interpro/protein/P08217
Peptidase S1, PA clan
1 reference
stated in
InterPro Release 71.0
reference URL
http://www.ebi.ac.uk/interpro/protein/P08217
Serine proteases, trypsin domain, protein family
1 reference
based on heuristic
inferred from protein domain or family
Serine proteases, trypsin family, histidine active site, protein family
1 reference
based on heuristic
inferred from protein domain or family
Serine proteases, trypsin family, serine active site, protein family
1 reference
based on heuristic
inferred from protein domain or family
found in taxon
Homo sapiens
1 reference
stated in
UniProt
retrieved
13 November 2019
UniProt protein ID
P08217
encoded by
CELA2A
1 reference
stated in
UniProt
retrieved
13 November 2019
UniProt protein ID
P08217
molecular function
serine hydrolase activity
determination method
IDA
1 reference
retrieved
8 April 2019
stated in
Elastase 2 is expressed in human and mouse epidermis and impairs skin barrier function in Netherton syndrome through filaggrin and lipid misprocessing
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P08217
determination method
IDA
peptidase activity
determination method
IEA
1 reference
retrieved
8 April 2019
stated in
GOA
curator
UniProt
UniProt protein ID
P08217
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P08217
determination method
IEA
serine-type peptidase activity
determination method
IEA
1 reference
retrieved
8 April 2019
stated in
GOA
curator
UniProt
UniProt protein ID
P08217
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P08217
determination method
IEA
hydrolase activity
determination method
IEA
1 reference
retrieved
8 April 2019
stated in
GOA
curator
UniProt
UniProt protein ID
P08217
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P08217
determination method
IEA
endopeptidase activity
determination method
TAS
1 reference
retrieved
10 September 2018
stated in
GOA
curator
Reactome
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P08217&geneProductId=UniProtKB:P08217
determination method
TAS
serine-type endopeptidase activity
determination method
IBA
IEA
TAS
3 references
retrieved
8 April 2019
stated in
Molecular cloning and expression in Escherichia coli of a cDNA encoding human pancreatic elastase 2
GOA
curator
Proteome Inc.
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P08217
determination method
TAS
retrieved
8 April 2019
stated in
GOA
curator
InterPro
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P08217
determination method
IEA
retrieved
8 April 2019
stated in
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
GOA
curator
GO Central
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P08217
determination method
IBA
cell component
keratohyalin granule
determination method
IDA
1 reference
retrieved
8 April 2019
stated in
Elastase 2 is expressed in human and mouse epidermis and impairs skin barrier function in Netherton syndrome through filaggrin and lipid misprocessing
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P08217
determination method
IDA
extracellular region
determination method
IEA
TAS
2 references
retrieved
8 April 2019
stated in
GOA
curator
Reactome
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P08217
determination method
TAS
retrieved
8 April 2019
stated in
GOA
curator
UniProt
UniProt protein ID
P08217
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P08217
determination method
IEA
extracellular space
determination method
IBA
1 reference
retrieved
8 April 2019
stated in
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
GOA
curator
GO Central
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P08217
determination method
IBA
cytosol
determination method
TAS
1 reference
retrieved
8 April 2019
stated in
GOA
curator
Reactome
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P08217
determination method
TAS
biological process
proteolysis
determination method
IEA
2 references
retrieved
27 March 2018
stated in
GOA
curator
UniProt
UniProt protein ID
P08217
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P08217&geneProductId=UniProtKB:P08217
determination method
IEA
retrieved
27 March 2018
stated in
GOA
curator
InterPro
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P08217&geneProductId=UniProtKB:P08217
determination method
IEA
cornification
determination method
TAS
1 reference
retrieved
8 April 2019
stated in
GOA
curator
Reactome
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P08217
determination method
TAS
proteolysis
determination method
IBA
IEA
3 references
retrieved
8 April 2019
stated in
GOA
curator
UniProt
UniProt protein ID
P08217
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P08217
determination method
IEA
retrieved
8 April 2019
stated in
GOA
curator
InterPro
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P08217
determination method
IEA
retrieved
8 April 2019
stated in
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
GOA
curator
GO Central
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P08217
determination method
IBA
has part(s)
serine proteases, trypsin family, histidine active site
1 reference
stated in
InterPro Release 71.0
reference URL
http://www.ebi.ac.uk/interpro/protein/P08217
serine proteases, trypsin domain
1 reference
stated in
InterPro Release 71.0
reference URL
http://www.ebi.ac.uk/interpro/protein/P08217
Serine proteases, trypsin family, serine active site
1 reference
stated in
InterPro Release 71.0
reference URL
http://www.ebi.ac.uk/interpro/protein/P08217
Identifiers
RefSeq protein ID
NP_254275
1 reference
stated in
NCBI Gene
retrieved
30 May 2020
Entrez Gene ID
63036
UniProt protein ID
P08217
1 reference
stated in
UniProt
retrieved
13 November 2019
UniProt protein ID
P08217
Ensembl protein ID
ENSP00000352639
1 reference
stated in
Ensembl Release 99
Ensembl protein ID
ENSP00000352639
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