(Q21117210)

glycoside hydrolase superfamily

1 reference

chitinase-3-like protein 1

1 reference

Chitinase II domain, protein family

1 reference

based on heuristic

inferred from protein domain or family

Glycoside hydrolase family 18, catalytic domain, protein family

1 reference

based on heuristic

inferred from protein domain or family

1 reference

13 November 2019

1 reference

13 November 2019

2 references

8 April 2019

Chitotriosidase, a chitinase, and the 39-kDa human cartilage glycoprotein, a chitin-binding lectin, are homologues of family 18 glycosyl hydrolases secreted by human macrophages

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P36222

8 April 2019

Human cartilage gp-39, a major secretory product of articular chondrocytes and synovial cells, is a mammalian member of a chitinase protein family

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P36222

extracellular matrix structural constituent

IDA

1 reference

8 April 2019

Human cartilage gp-39, a major secretory product of articular chondrocytes and synovial cells, is a mammalian member of a chitinase protein family

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P36222

3 references

26 September 2017

http://www.ebi.ac.uk/QuickGO/annotations?protein=P36222&geneProductId=UniProtKB:P36222

26 September 2017

Chitotriosidase, a chitinase, and the 39-kDa human cartilage glycoprotein, a chitin-binding lectin, are homologues of family 18 glycosyl hydrolases secreted by human macrophages

http://www.ebi.ac.uk/QuickGO/annotations?protein=P36222&geneProductId=UniProtKB:P36222

26 September 2017

Structure and ligand-induced conformational change of the 39-kDa glycoprotein from human articular chondrocytes

http://www.ebi.ac.uk/QuickGO/annotations?protein=P36222&geneProductId=UniProtKB:P36222

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P36222

3 references

8 April 2019

Galectin-3 Interacts with the CHI3L1 Axis and Contributes to Hermansky-Pudlak Syndrome Lung Disease.

GOA

curator

IntAct protein interaction database

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P36222

8 April 2019

IL-13Rα2 uses TMEM219 in chitinase 3-like-1-induced signalling and effector responses

GOA

curator

IntAct protein interaction database

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P36222

8 April 2019

Tumor-recruited M2 macrophages promote gastric and breast cancer metastasis via M2 macrophage-secreted CHI3L1 protein

GOA

curator

IntAct protein interaction database

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P36222

4 references

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P36222

8 April 2019

Chitotriosidase, a chitinase, and the 39-kDa human cartilage glycoprotein, a chitin-binding lectin, are homologues of family 18 glycosyl hydrolases secreted by human macrophages

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P36222

8 April 2019

Structure and ligand-induced conformational change of the 39-kDa glycoprotein from human articular chondrocytes

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P36222

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P36222

IBA

cell component

endoplasmic reticulum

ISS

perinuclear region of cytoplasm

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P36222

http://www.ebi.ac.uk/QuickGO/annotations?protein=P36222&geneProductId=UniProtKB:P36222

extracellular exosome

2 references

6 references

26 September 2017

26 September 2017

http://www.ebi.ac.uk/QuickGO/annotations?protein=P36222&geneProductId=UniProtKB:P36222

26 September 2017

http://www.ebi.ac.uk/QuickGO/annotations?protein=P36222&geneProductId=UniProtKB:P36222

26 September 2017

Chitotriosidase, a chitinase, and the 39-kDa human cartilage glycoprotein, a chitin-binding lectin, are homologues of family 18 glycosyl hydrolases secreted by human macrophages

http://www.ebi.ac.uk/QuickGO/annotations?protein=P36222&geneProductId=UniProtKB:P36222

26 September 2017

Human cartilage gp-39, a major secretory product of articular chondrocytes and synovial cells, is a mammalian member of a chitinase protein family

http://www.ebi.ac.uk/QuickGO/annotations?protein=P36222&geneProductId=UniProtKB:P36222

26 September 2017

Human colostrum: identification of minor proteins in the aqueous phase by proteomics

http://www.ebi.ac.uk/QuickGO/annotations?protein=P36222&geneProductId=UniProtKB:P36222

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P36222

IDA

specific granule lumen

1 reference

8 April 2019

4 references

26 September 2017

http://www.ebi.ac.uk/QuickGO/annotations?protein=P36222&geneProductId=UniProtKB:P36222

26 September 2017

http://www.ebi.ac.uk/QuickGO/annotations?protein=P36222&geneProductId=UniProtKB:P36222

26 September 2017

http://www.ebi.ac.uk/QuickGO/annotations?protein=P36222&geneProductId=UniProtKB:P36222

26 September 2017

http://www.ebi.ac.uk/QuickGO/annotations?protein=P36222&geneProductId=UniProtKB:P36222

6 references

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P36222

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P36222

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P36222

8 April 2019

Chitotriosidase, a chitinase, and the 39-kDa human cartilage glycoprotein, a chitin-binding lectin, are homologues of family 18 glycosyl hydrolases secreted by human macrophages

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P36222

8 April 2019

Human cartilage gp-39, a major secretory product of articular chondrocytes and synovial cells, is a mammalian member of a chitinase protein family

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P36222

8 April 2019

Human colostrum: identification of minor proteins in the aqueous phase by proteomics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P36222

1 reference

8 April 2019

Human cartilage gp-39, a major secretory product of articular chondrocytes and synovial cells, is a mammalian member of a chitinase protein family

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P36222

In-depth proteomic analyses of exosomes isolated from expressed prostatic secretions in urine

NAS

extracellular exosome

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P36222

response to interleukin-1

HDA

biological process

1 reference

8 April 2019

Inflammatory cytokines induce production of CHI3L1 by articular chondrocytes

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P36222

response to interleukin-6

IEP

1 reference

8 April 2019

IL-6, but not TNF-α, increases plasma YKL-40 in human subjects

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P36222

1 reference

8 April 2019

Effect of variation in CHI3L1 on serum YKL-40 level, risk of asthma, and lung function

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P36222

response to mechanical stimulus

IMP

1 reference

8 April 2019

The chitinase-like protein YKL-40 is secreted by airway epithelial cells at base line and in response to compressive mechanical stress

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P36222

response to tumor necrosis factor

IEP

1 reference

8 April 2019

Inflammatory cytokines induce production of CHI3L1 by articular chondrocytes

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P36222

Human cartilage gp-39, a major secretory product of articular chondrocytes and synovial cells, is a mammalian member of a chitinase protein family

IEP

cartilage development

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P36222

cellular response to interleukin-1

NAS

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P36222

positive regulation of ERK1 and ERK2 cascade

1 reference

8 April 2019

Role of YKL-40 in the angiogenesis, radioresistance, and progression of glioblastoma

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P36222

Inflammatory cytokines induce production of CHI3L1 by articular chondrocytes

IMP

inflammatory response

3 references

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P36222

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P36222

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P36222

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P36222

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P36222

neutrophil degranulation

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?protein=P36222&geneProductId=UniProtKB:P36222

TAS

chitin catabolic process

1 reference

26 September 2017

carbohydrate metabolic process

IBA

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P36222

Glycoside hydrolase family 18, catalytic domain

has part(s)

1 reference

Chitinase II domain

1 reference

Identifiers

1 reference

30 May 2020

1 reference

13 November 2019

1 reference

1 reference

1 reference

21 March 2016

1 reference

21 March 2016

1 reference

21 March 2016

1 reference

21 March 2016

1 reference

21 March 2016

1 reference

21 March 2016

1 reference

21 March 2016