(Q21117304)

http://www.ebi.ac.uk/interpro/protein/Q02928

cytochrome P450, E-class, group I

1 reference

stated in

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/Q02928

cytochrome P450, conserved site, protein family

1 reference

based on heuristic

inferred from protein domain or family

1 reference

13 November 2019

1 reference

13 November 2019

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q02928

leukotriene-B4 20-monooxygenase activity

1 reference

8 April 2019

Role of human CYP4F2 in hepatic catabolism of the proinflammatory agent leukotriene B4

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q02928

arachidonic acid epoxygenase activity

1 reference

8 April 2019

Metabolism of arachidonic acid to 20-hydroxy-5,8,11, 14-eicosatetraenoic acid by P450 enzymes in human liver: involvement of CYP4F2 and CYP4A11

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q02928

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q02928

alkane 1-monooxygenase activity

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q02928

oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q02928

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q02928

oxidoreductase activity

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q02928

monooxygenase activity

1 reference

8 April 2019

1 reference

8 April 2019

Formation of 20-hydroxyeicosatetraenoic acid, a vasoactive and natriuretic eicosanoid, in human kidney. Role of Cyp4F2 and Cyp4A11

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q02928

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q02928

intracellular membrane-bounded organelle

4 references

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q02928

8 April 2019

Formation of 20-hydroxyeicosatetraenoic acid, a vasoactive and natriuretic eicosanoid, in human kidney. Role of Cyp4F2 and Cyp4A11

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q02928

8 April 2019

Role of human CYP4F2 in hepatic catabolism of the proinflammatory agent leukotriene B4

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q02928

8 April 2019

Metabolism of arachidonic acid to 20-hydroxy-5,8,11, 14-eicosatetraenoic acid by P450 enzymes in human liver: involvement of CYP4F2 and CYP4A11

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q02928

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q02928

Formation of 20-hydroxyeicosatetraenoic acid, a vasoactive and natriuretic eicosanoid, in human kidney. Role of Cyp4F2 and Cyp4A11

apical plasma membrane

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q02928

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q02928

endoplasmic reticulum

1 reference

8 April 2019

leukotriene metabolic process

biological process

1 reference

8 April 2019

Role of human CYP4F2 in hepatic catabolism of the proinflammatory agent leukotriene B4

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q02928

Metabolism of arachidonic acid to 20-hydroxy-5,8,11, 14-eicosatetraenoic acid by P450 enzymes in human liver: involvement of CYP4F2 and CYP4A11

epoxygenase P450 pathway

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q02928

1 reference

8 April 2019

Formation of 20-hydroxyeicosatetraenoic acid, a vasoactive and natriuretic eicosanoid, in human kidney. Role of Cyp4F2 and Cyp4A11

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q02928

omega-hydroxylase P450 pathway

IEP

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q02928

Formation of 20-hydroxyeicosatetraenoic acid, a vasoactive and natriuretic eicosanoid, in human kidney. Role of Cyp4F2 and Cyp4A11

TAS

renal water homeostasis

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q02928

positive regulation of icosanoid secretion

IEP

1 reference

8 April 2019

A single nucleotide polymorphism in the CYP4F2 but not CYP4A11 gene is associated with increased 20-HETE excretion and blood pressure

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q02928

Formation of 20-hydroxyeicosatetraenoic acid, a vasoactive and natriuretic eicosanoid, in human kidney. Role of Cyp4F2 and Cyp4A11

IMP

sodium ion homeostasis

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q02928

long-chain fatty acid metabolic process

IEP

1 reference

8 April 2019

Cytochrome P450 omega hydroxylase (CYP4) function in fatty acid metabolism and metabolic diseases

GOA

curator

British Heart Foundation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q02928

leukotriene B4 catabolic process

1 reference

8 April 2019

Gene Ontology Consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q02928

arachidonic acid metabolic process

1 reference

8 April 2019

Formation of 20-hydroxyeicosatetraenoic acid, a vasoactive and natriuretic eicosanoid, in human kidney. Role of Cyp4F2 and Cyp4A11

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q02928

regulation of lipid metabolic process

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q02928

cytochrome P450, conserved site

TAS

EC enzyme number

1.14.14.80

1 reference

9 September 2019

1 reference

stated in

InterPro Release 71.0