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NADH dehydrogenase, subunit 5 (complex I)
mammalian protein found in Homo sapiens
ND5
NADH dehydrogenase subunit 5
In more languages
edit
Statements
instance of
protein
1 reference
stated in
UniProt
retrieved
13 November 2019
UniProt protein ID
P03915
part of
NADH-plastoquinone oxidoreductase, chain 5
1 reference
stated in
InterPro Release 71.0
reference URL
http://www.ebi.ac.uk/interpro/protein/P03915
NADH dehydrogenase subunit 5, C-terminal domain, protein family
1 reference
based on heuristic
inferred from protein domain or family
NADH:quinone oxidoreductase/Mrp antiporter, membrane subunit, protein family
1 reference
based on heuristic
inferred from protein domain or family
NADH-Ubiquinone oxidoreductase (complex I), chain 5 N-terminal domain, protein family
1 reference
based on heuristic
inferred from protein domain or family
found in taxon
Homo sapiens
1 reference
stated in
UniProt
retrieved
13 November 2019
UniProt protein ID
P03915
encoded by
ND5
1 reference
stated in
UniProt
retrieved
13 November 2019
UniProt protein ID
P03915
molecular function
NADH dehydrogenase (ubiquinone) activity
determination method
NAS
IEA
2 references
retrieved
8 April 2019
stated in
Six unidentified reading frames of human mitochondrial DNA encode components of the respiratory-chain NADH dehydrogenase
GOA
curator
UniProt
UniProt protein ID
P03915
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P03915
determination method
NAS
retrieved
8 April 2019
stated in
GOA
curator
InterPro
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P03915
determination method
IEA
oxidoreductase activity
determination method
IEA
1 reference
retrieved
27 March 2018
stated in
GOA
curator
UniProt
UniProt protein ID
P03915
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P03915&geneProductId=UniProtKB:P03915
determination method
IEA
NADH dehydrogenase activity
determination method
IEA
1 reference
retrieved
8 April 2019
stated in
GOA
curator
Ensembl genome database project
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P03915
determination method
IEA
cell component
integral component of membrane
determination method
IEA
1 reference
retrieved
8 April 2019
stated in
GOA
curator
UniProt
UniProt protein ID
P03915
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P03915
determination method
IEA
mitochondrial inner membrane
determination method
TAS
IEA
2 references
retrieved
8 April 2019
stated in
GOA
curator
Reactome
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P03915
determination method
TAS
retrieved
8 April 2019
stated in
GOA
curator
UniProt
UniProt protein ID
P03915
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P03915
determination method
IEA
neuron projection
determination method
IEA
1 reference
retrieved
8 April 2019
stated in
GOA
curator
Ensembl genome database project
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P03915
determination method
IEA
mitochondrial respiratory chain complex I
determination method
NAS
IDA
2 references
retrieved
8 April 2019
stated in
Six unidentified reading frames of human mitochondrial DNA encode components of the respiratory-chain NADH dehydrogenase
GOA
curator
UniProt
UniProt protein ID
P03915
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P03915
determination method
NAS
retrieved
8 April 2019
stated in
The subunit composition of the human NADH dehydrogenase obtained by rapid one-step immunopurification
GOA
curator
UniProt
UniProt protein ID
P03915
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P03915
determination method
IDA
respirasome
determination method
IEA
1 reference
retrieved
8 April 2019
stated in
GOA
curator
UniProt
UniProt protein ID
P03915
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P03915
determination method
IEA
membrane
determination method
IEA
1 reference
retrieved
8 April 2019
stated in
GOA
curator
UniProt
UniProt protein ID
P03915
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P03915
determination method
IEA
mitochondrion
determination method
IEA
1 reference
retrieved
8 April 2019
stated in
GOA
curator
UniProt
UniProt protein ID
P03915
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P03915
determination method
IEA
biological process
ATP synthesis coupled electron transport
determination method
IEA
1 reference
retrieved
8 April 2019
stated in
GOA
curator
InterPro
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P03915
determination method
IEA
response to hypoxia
determination method
IEA
1 reference
retrieved
8 April 2019
stated in
GOA
curator
Ensembl genome database project
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P03915
determination method
IEA
response to hydrogen peroxide
determination method
IEA
1 reference
retrieved
8 April 2019
stated in
GOA
curator
Ensembl genome database project
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P03915
determination method
IEA
response to organonitrogen compound
determination method
IEA
1 reference
retrieved
8 April 2019
stated in
GOA
curator
Ensembl genome database project
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P03915
determination method
IEA
mitochondrial respiratory chain complex I assembly
determination method
TAS
1 reference
retrieved
8 April 2019
stated in
GOA
curator
Reactome
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P03915
determination method
TAS
mitochondrial electron transport, NADH to ubiquinone
determination method
NAS
TAS
2 references
retrieved
8 April 2019
stated in
GOA
curator
Reactome
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P03915
determination method
TAS
retrieved
8 April 2019
stated in
Six unidentified reading frames of human mitochondrial DNA encode components of the respiratory-chain NADH dehydrogenase
GOA
curator
UniProt
UniProt protein ID
P03915
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P03915
determination method
NAS
mitochondrial electron transport, NADH to ubiquinone
determination method
NAS
1 reference
retrieved
1 January 2018
stated in
Six unidentified reading frames of human mitochondrial DNA encode components of the respiratory-chain NADH dehydrogenase
GOA
curator
UniProt
UniProt protein ID
P03915
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P03915&geneProductId=UniProtKB:P03915
determination method
NAS
physically interacts with
metformin
object has role
reaction inhibitor
1 reference
stated in
Open Targets Platform
retrieved
14 August 2023
reference URL
https://platform.opentargets.org/drug/CHEMBL1431
metformin hydrochloride
object has role
reaction inhibitor
1 reference
stated in
Open Targets Platform
retrieved
14 August 2023
reference URL
https://platform.opentargets.org/drug/CHEMBL1703
has part(s)
NADH dehydrogenase subunit 5, C-terminal
1 reference
stated in
InterPro Release 71.0
reference URL
http://www.ebi.ac.uk/interpro/protein/P03915
NADH-Ubiquinone oxidoreductase (complex I), chain 5 N-terminal
1 reference
stated in
InterPro Release 71.0
reference URL
http://www.ebi.ac.uk/interpro/protein/P03915
NADH:quinone oxidoreductase/Mrp antiporter, membrane subunit
1 reference
stated in
InterPro Release 71.0
reference URL
http://www.ebi.ac.uk/interpro/protein/P03915
Identifiers
RefSeq protein ID
YP_003024036
1 reference
stated in
NCBI Gene
retrieved
30 May 2020
Entrez Gene ID
4540
UniProt protein ID
P03915
1 reference
stated in
UniProt
retrieved
13 November 2019
UniProt protein ID
P03915
Ensembl protein ID
ENSP00000354813
1 reference
stated in
Ensembl Release 99
Ensembl protein ID
ENSP00000354813
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