(Q21117635)

English

Profilin 2

mammalian protein found in Homo sapiens

profilin-2
PFN2
profilin II

In more languages

Statements

1 reference

13 November 2019

UniProt protein ID

Profilin superfamily

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/P35080

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/P35080

Profilin conserved site, protein family

1 reference

based on heuristic

inferred from protein domain or family

1 reference

13 November 2019

UniProt protein ID

1 reference

13 November 2019

UniProt protein ID

molecular function

determination method

2 references

phosphatidylinositol-4,5-bisphosphate binding

determination method

1 reference

8 April 2019

Distinct biochemical characteristics of the two human profilin isoforms

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35080

determination method

actin monomer binding

determination method

1 reference

8 April 2019

Distinct biochemical characteristics of the two human profilin isoforms

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35080

determination method

protein binding

determination method

3 references

8 April 2019

A protein interaction network links GIT1, an enhancer of huntingtin aggregation, to Huntington's disease

IntAct protein interaction database

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35080

determination method

8 April 2019

The essential role of profilin in the assembly of actin for microspike formation

IntAct protein interaction database

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35080

determination method

8 April 2019

A human protein-protein interaction network: a resource for annotating the proteome

IntAct protein interaction database

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35080

determination method

ATPase activity

determination method

1 reference

8 April 2019

Distinct biochemical characteristics of the two human profilin isoforms

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35080

determination method

determination method

terminal bouton

determination method

1 reference

26 September 2017

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?protein=P35080&geneProductId=UniProtKB:P35080

determination method

determination method

1 reference

8 April 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35080

determination method

extracellular exosome

determination method

1 reference

8 April 2019

Large-scale proteomics and phosphoproteomics of urinary exosomes

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35080

determination method

Schaffer collateral - CA1 synapse

determination method

1 reference

8 April 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35080

determination method

determination method

1 reference

8 April 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35080

determination method

determination method

1 reference

8 April 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35080

determination method

glutamatergic synapse

determination method

1 reference

8 April 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35080

determination method

biological process

regulation of actin filament polymerization

determination method

1 reference

26 September 2017

http://www.ebi.ac.uk/QuickGO/annotations?protein=P35080&geneProductId=UniProtKB:P35080

determination method

regulation of synaptic vesicle exocytosis

determination method

1 reference

8 April 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35080

determination method

protein stabilization

determination method

1 reference

8 April 2019

Phosphorylation of profilin by ROCK1 regulates polyglutamine aggregation

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35080

determination method

positive regulation of actin filament bundle assembly

determination method

1 reference

26 September 2017

Differential remodeling of actin cytoskeleton architecture by profilin isoforms leads to distinct effects on cell migration and invasion

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?protein=P35080&geneProductId=UniProtKB:P35080

determination method

positive regulation of ATP-dependent activity

determination method

1 reference

8 April 2019

Distinct biochemical characteristics of the two human profilin isoforms

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35080

determination method

actin cytoskeleton organization

determination method

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35080

determination method

negative regulation of actin filament polymerization

determination method

1 reference

8 April 2019

Distinct biochemical characteristics of the two human profilin isoforms

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35080

determination method

positive regulation of actin filament bundle assembly

determination method

modification of postsynaptic actin cytoskeleton

determination method

1 reference

8 April 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35080

determination method

Profilin conserved site

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/P35080

Identifiers

RefSeq protein ID

1 reference

30 May 2020

1 reference

30 May 2020

UniProt protein ID

1 reference

13 November 2019

UniProt protein ID

Ensembl protein ID

ENSP00000239940

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000239940

ENSP00000410464

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000410464

ENSP00000408283

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000408283

ENSP00000417351

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000417351

ENSP00000417817

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000417817

ENSP00000417912

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000417912

ENSP00000417924

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000417924

ENSP00000418142

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000418142

ENSP00000418216

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000418216

ENSP00000418494

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000418494

ENSP00000418521

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000418521

ENSP00000418523

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000418523

ENSP00000420202

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000420202

ENSP00000420244

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000420244

ENSP00000420417

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000420417

ENSP00000420504

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000420504

ENSP00000498146

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000498146

PDB structure ID

1 reference

UniProt protein ID

21 March 2016

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