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DNA polymerase delta 4, accessory subunit
mammalian protein found in Homo sapiens
DNA polymerase delta subunit p12
polymerase (DNA) delta 4, accessory subunit
DNA polymerase delta smallest subunit p12
polymerase (DNA-directed), delta 4, accessory subunit
DNA polymerase delta subunit 4
POLD4
In more languages
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Statements
instance of
protein
1 reference
stated in
UniProt
retrieved
13 November 2019
UniProt protein ID
Q9HCU8
part of
DNA polymerase delta, subunit 4
1 reference
stated in
InterPro Release 71.0
reference URL
http://www.ebi.ac.uk/interpro/protein/Q9HCU8
found in taxon
Homo sapiens
1 reference
stated in
UniProt
retrieved
13 November 2019
UniProt protein ID
Q9HCU8
encoded by
POLD4
1 reference
stated in
UniProt
retrieved
13 November 2019
UniProt protein ID
Q9HCU8
molecular function
protein binding
determination method
IPI
5 references
retrieved
8 April 2019
stated in
Human Werner helicase interacting protein 1 (WRNIP1) functions as a novel modulator for DNA polymerase delta
GOA
curator
UniProt
UniProt protein ID
Q9HCU8
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9HCU8
determination method
IPI
retrieved
8 April 2019
stated in
Human Werner helicase interacting protein 1 (WRNIP1) functions as a novel modulator for DNA polymerase delta
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9HCU8
determination method
IPI
retrieved
8 April 2019
stated in
A human interactome in three quantitative dimensions organized by stoichiometries and abundances
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9HCU8
determination method
IPI
retrieved
8 April 2019
stated in
Reconstitution and characterization of the human DNA polymerase delta four-subunit holoenzyme
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9HCU8
determination method
IPI
retrieved
8 April 2019
stated in
Functional roles of p12, the fourth subunit of human DNA polymerase delta
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9HCU8
determination method
IPI
DNA-directed DNA polymerase activity
determination method
IBA
TAS
2 references
retrieved
10 September 2018
stated in
GOA
curator
Reactome
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9HCU8&geneProductId=UniProtKB:Q9HCU8
determination method
TAS
retrieved
10 September 2018
stated in
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
GOA
curator
GO Central
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9HCU8&geneProductId=UniProtKB:Q9HCU8
determination method
IBA
DNA-directed DNA polymerase activity
determination method
IBA
1 reference
retrieved
8 April 2019
stated in
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
GOA
curator
GO Central
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9HCU8
determination method
IBA
cell component
delta DNA polymerase complex
determination method
IBA
1 reference
retrieved
8 April 2019
stated in
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
GOA
curator
GO Central
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9HCU8
determination method
IBA
nucleoplasm
determination method
TAS
1 reference
retrieved
8 April 2019
stated in
GOA
curator
Reactome
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9HCU8
determination method
TAS
nucleolus
determination method
IDA
1 reference
retrieved
8 April 2019
stated in
GOA
curator
Human Protein Atlas
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9HCU8
determination method
IDA
mitochondrion
determination method
IDA
1 reference
retrieved
8 April 2019
stated in
GOA
curator
Human Protein Atlas
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9HCU8
determination method
IDA
cytosol
determination method
IDA
1 reference
retrieved
8 April 2019
stated in
GOA
curator
Human Protein Atlas
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9HCU8
determination method
IDA
nucleus
determination method
IDA
IEA
3 references
retrieved
8 April 2019
stated in
GOA
curator
UniProt
UniProt protein ID
Q9HCU8
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9HCU8
determination method
IEA
retrieved
8 April 2019
stated in
GOA
curator
InterPro
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9HCU8
determination method
IEA
retrieved
8 April 2019
stated in
GOA
curator
Human Protein Atlas
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9HCU8
determination method
IDA
biological process
DNA-dependent DNA replication
determination method
IBA
1 reference
retrieved
8 April 2019
stated in
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
GOA
curator
GO Central
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9HCU8
determination method
IBA
nucleotide-excision repair, DNA gap filling
determination method
TAS
1 reference
retrieved
8 April 2019
stated in
GOA
curator
Reactome
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9HCU8
determination method
TAS
DNA synthesis involved in DNA repair
determination method
IBA
1 reference
retrieved
24 April 2018
stated in
GOA
curator
GO Central
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9HCU8&geneProductId=UniProtKB:Q9HCU8
determination method
IBA
translesion synthesis
determination method
TAS
1 reference
retrieved
8 April 2019
stated in
GOA
curator
Reactome
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9HCU8
determination method
TAS
transcription-coupled nucleotide-excision repair
determination method
TAS
1 reference
retrieved
8 April 2019
stated in
GOA
curator
Reactome
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9HCU8
determination method
TAS
nucleotide-excision repair, DNA incision
determination method
TAS
1 reference
retrieved
8 April 2019
stated in
GOA
curator
Reactome
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9HCU8
determination method
TAS
telomere maintenance
determination method
TAS
1 reference
retrieved
8 April 2019
stated in
GOA
curator
Reactome
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9HCU8
determination method
TAS
nucleotide-excision repair, DNA incision, 5'-to lesion
determination method
TAS
1 reference
retrieved
8 April 2019
stated in
GOA
curator
Reactome
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9HCU8
determination method
TAS
DNA repair
determination method
IEA
1 reference
retrieved
8 April 2019
stated in
GOA
curator
UniProt
UniProt protein ID
Q9HCU8
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9HCU8
determination method
IEA
cellular response to DNA damage stimulus
determination method
IEA
1 reference
retrieved
8 April 2019
stated in
GOA
curator
UniProt
UniProt protein ID
Q9HCU8
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9HCU8
determination method
IEA
telomere maintenance via semi-conservative replication
determination method
TAS
1 reference
retrieved
8 April 2019
stated in
GOA
curator
Reactome
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9HCU8
determination method
TAS
DNA replication
determination method
IEA
2 references
retrieved
8 April 2019
stated in
GOA
curator
UniProt
UniProt protein ID
Q9HCU8
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9HCU8
determination method
IEA
retrieved
8 April 2019
stated in
GOA
curator
InterPro
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9HCU8
determination method
IEA
DNA mismatch repair
determination method
TAS
1 reference
retrieved
8 April 2019
stated in
GOA
curator
Reactome
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9HCU8
determination method
TAS
physically interacts with
cytarabine
object has role
reaction inhibitor
1 reference
stated in
Open Targets Platform
retrieved
14 August 2023
reference URL
https://platform.opentargets.org/drug/CHEMBL803
fludarabine phosphate
object has role
reaction inhibitor
1 reference
stated in
Open Targets Platform
retrieved
14 August 2023
reference URL
https://platform.opentargets.org/drug/CHEMBL1096882
gemcitabine hydrochloride
object has role
reaction inhibitor
1 reference
stated in
Open Targets Platform
retrieved
14 August 2023
reference URL
https://platform.opentargets.org/drug/CHEMBL1637
Identifiers
RefSeq protein ID
NP_001243799
1 reference
stated in
NCBI Gene
retrieved
30 May 2020
Entrez Gene ID
57804
NP_066996
1 reference
stated in
NCBI Gene
retrieved
30 May 2020
Entrez Gene ID
57804
UniProt protein ID
Q9HCU8
1 reference
stated in
UniProt
retrieved
13 November 2019
UniProt protein ID
Q9HCU8
Ensembl protein ID
ENSP00000311368
1 reference
stated in
Ensembl Release 99
Ensembl protein ID
ENSP00000311368
ENSP00000444780
1 reference
stated in
Ensembl Release 99
Ensembl protein ID
ENSP00000444780
ENSP00000433408
1 reference
stated in
Ensembl Release 99
Ensembl protein ID
ENSP00000433408
ENSP00000436361
1 reference
stated in
Ensembl Release 99
Ensembl protein ID
ENSP00000436361
ENSP00000479678
1 reference
stated in
Ensembl Release 99
Ensembl protein ID
ENSP00000479678
ENSP00000481251
1 reference
stated in
Ensembl Release 99
Ensembl protein ID
ENSP00000481251
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