(Q21118676)

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/P32245

G protein-coupled receptor

1 reference

Transporter Classification Database ID

9.A.14.2.3

hierarchical database ID heuristic

2 October 2019

based on heuristic

GPCR, rhodopsin-like, 7TM, protein family

1 reference

based on heuristic

inferred from protein domain or family

1 reference

13 November 2019

1 reference

13 November 2019

signal transducer activity

http://www.ebi.ac.uk/QuickGO/annotations?protein=P32245&geneProductId=UniProtKB:P32245

1 reference

1 January 2018

peptide hormone binding

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P32245

melanocyte-stimulating hormone receptor activity

Novel binding motif of ACTH analogues at the melanocortin receptors

3 references

8 April 2019

British Heart Foundation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P32245

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P32245

8 April 2019

Identification and characterization of melanocortin-4 receptor gene mutations in morbidly obese finnish children and adults

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P32245

IDA

protein binding

4 references

8 April 2019

The cytosolic chaperone Hsc70 promotes traffic to the cell surface of intracellular retained melanocortin-4 receptor mutants

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P32245

8 April 2019

MRAP and MRAP2 are bidirectional regulators of the melanocortin receptor family

IntAct protein interaction database

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P32245

8 April 2019

MRAP and MRAP2 are bidirectional regulators of the melanocortin receptor family

British Heart Foundation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P32245

8 April 2019

Novel binding motif of ACTH analogues at the melanocortin receptors

British Heart Foundation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P32245

melanocortin receptor activity

Morphine down-regulates melanocortin-4 receptor expression in brain regions that mediate opiate addiction

3 references

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P32245

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P32245

8 April 2019

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P32245

ubiquitin protein ligase binding

1 reference

8 April 2019

Mahogunin ring finger-1 (MGRN1) E3 ubiquitin ligase inhibits signaling from melanocortin receptor by competition with Galphas

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P32245

neuropeptide binding

IMP

1 reference

8 April 2019

Functional analysis of the Ala67Thr polymorphism in agouti related protein associated with anorexia nervosa and leanness

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P32245

IMP

hormone binding

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P32245

integral component of membrane

cell component

Molecular cloning, expression, and gene localization of a fourth melanocortin receptor

3 references

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P32245

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P32245

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P32245

8 April 2019

membrane

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P32245

1 reference

8 April 2019

plasma membrane

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P32245

4 references

8 April 2019

8 April 2019

Functional characterization of mutations in melanocortin-4 receptor associated with human obesity

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P32245

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P32245

8 April 2019

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P32245

nucleus

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P32245

regulation of grooming behavior

biological process

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P32245

adenylate cyclase-modulating G protein-coupled receptor signaling pathway

1 reference

8 April 2019

Morphine down-regulates melanocortin-4 receptor expression in brain regions that mediate opiate addiction

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P32245

insulin secretion

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P32245

regulation of feeding behavior

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P32245

diet induced thermogenesis

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P32245

response to insulin

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P32245

negative regulation of feeding behavior

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P32245

energy reserve metabolic process

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P32245

regulation of metabolic process

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P32245

signal transduction

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P32245

1 reference

8 April 2019

G protein-coupled receptor signaling pathway

physically interacts with

1 reference

IUPHAR/BPS Guide to PHARMACOLOGY

Guide to Pharmacology Ligand ID

1324

language of work or name

17 August 2016

1 reference

IUPHAR/BPS Guide to PHARMACOLOGY

Guide to Pharmacology Ligand ID

1323

language of work or name

17 August 2016

1 reference

IUPHAR/BPS Guide to PHARMACOLOGY

Guide to Pharmacology Ligand ID

1338

language of work or name

English

object of statement has role

17 August 2016

setmelanotide

agonist

1 reference

Open Targets Platform

14 August 2023

https://platform.opentargets.org/drug/CHEMBL3301624

has part(s)

GPCR, rhodopsin-like, 7TM

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/P32245

Identifiers

1 reference

30 May 2020

1 reference

13 November 2019

1 reference

0 references

Microsoft Academic ID

0 references

0 references

1 reference

26 January 2022

https://docs.openalex.org/download-snapshot/snapshot-data-format

1 reference

14 November 2015

http://www.uniprot.org/uniprot/P32245.txt?version=164

1 reference

14 November 2015

http://www.uniprot.org/uniprot/P32245.txt?version=164

1 reference

14 November 2015

http://www.uniprot.org/uniprot/P32245.txt?version=164

1 reference

14 November 2015

http://www.uniprot.org/uniprot/P32245.txt?version=164

1 reference

14 November 2015

http://www.uniprot.org/uniprot/P32245.txt?version=164

1 reference

14 November 2015

http://www.uniprot.org/uniprot/P32245.txt?version=164

Transporter Classification Database ID

9.A.14.2.3

2 references

Transporter Classification database

13 March 2020

Transporter Classification database