(Q21118717)

MADS MEF2-like, protein family

1 reference

based on heuristic

inferred from protein domain or family

Holliday junction regulator protein family C-terminal domain, protein family

1 reference

based on heuristic

inferred from protein domain or family

Transcription factor, MADS-box, protein family

1 reference

based on heuristic

inferred from protein domain or family

1 reference

13 November 2019

1 reference

13 November 2019

protein dimerization activity

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q06413

DNA-binding transcription activator activity, RNA polymerase II-specific

4 references

5 June 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q06413&geneProductId=UniProtKB:Q06413

5 June 2018

Cooperative activation of atrial naturetic peptide promoter by dHAND and MEF2C

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q06413&geneProductId=UniProtKB:Q06413

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q06413

8 April 2019

Cooperative activation of atrial naturetic peptide promoter by dHAND and MEF2C

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q06413

histone deacetylase binding

1 reference

5 June 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q06413&geneProductId=UniProtKB:Q06413

RNA polymerase II general transcription initiation factor activity

core promoter sequence-specific DNA binding

1 reference

27 March 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q06413&geneProductId=UniProtKB:Q06413

RNA polymerase II transcription regulatory region sequence-specific DNA binding

HMG box domain binding

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q06413

DNA-binding transcription activator activity, RNA polymerase II-specific

1 reference

5 June 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q06413&geneProductId=UniProtKB:Q06413

minor groove of adenine-thymine-rich DNA binding

1 reference

8 April 2019

Cooperative activation of atrial naturetic peptide promoter by dHAND and MEF2C

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q06413

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q06413

cis-regulatory region sequence-specific DNA binding

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q06413

6 references

8 April 2019

Cooperative activation of atrial naturetic peptide promoter by dHAND and MEF2C

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q06413

8 April 2019

The Notch coactivator, MAML1, functions as a novel coactivator for MEF2C-mediated transcription and is required for normal myogenesis

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q06413

8 April 2019

Skeletal myosin light chain kinase regulates skeletal myogenesis by phosphorylation of MEF2C

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q06413

8 April 2019

TGF-beta activates ERK5 in human renal epithelial cells

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q06413

8 April 2019

Skeletal myosin light chain kinase regulates skeletal myogenesis by phosphorylation of MEF2C

IntAct protein interaction database

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q06413

8 April 2019

MEF2-dependent recruitment of the HAND1 transcription factor results in synergistic activation of target promoters

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q06413

4 references

5 June 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q06413&geneProductId=UniProtKB:Q06413

5 June 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q06413&geneProductId=UniProtKB:Q06413

5 June 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q06413&geneProductId=UniProtKB:Q06413

5 June 2018

Functional regulatory regions of human transcription factor MEF2C

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q06413&geneProductId=UniProtKB:Q06413

sequence-specific DNA binding

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q06413

protein heterodimerization activity

1 reference

8 April 2019

Regulation of the MEF2 family of transcription factors by p38

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q06413

transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding

IPI

1 reference

10 September 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q06413&geneProductId=UniProtKB:Q06413

DNA-binding transcription factor activity, RNA polymerase II-specific

5 references

7 November 2018

A census of human transcription factors: function, expression and evolution

Norwegian University of Science and Technology, Systems Biology team

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q06413&geneProductId=UniProtKB:Q06413

7 November 2018

The MADS box transcription factor MEF2C regulates melanocyte development and is a direct transcriptional target and partner of SOX10

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q06413&geneProductId=UniProtKB:Q06413

7 November 2018

A census of human transcription factors: function, expression and evolution

Norwegian University of Science and Technology, Systems Biology team

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q06413&geneProductId=UniProtKB:Q06413

7 November 2018

Norwegian University of Science and Technology, Systems Biology team

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q06413&geneProductId=UniProtKB:Q06413

7 November 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q06413&geneProductId=UniProtKB:Q06413

DNA-binding transcription activator activity, RNA polymerase II-specific

6 references

10 September 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q06413&geneProductId=UniProtKB:Q06413

10 September 2018

Cooperative activation of atrial naturetic peptide promoter by dHAND and MEF2C

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q06413&geneProductId=UniProtKB:Q06413

10 September 2018

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q06413&geneProductId=UniProtKB:Q06413

7 November 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q06413&geneProductId=UniProtKB:Q06413

7 November 2018

Cooperative activation of atrial naturetic peptide promoter by dHAND and MEF2C

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q06413&geneProductId=UniProtKB:Q06413

7 November 2018

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q06413&geneProductId=UniProtKB:Q06413

DNA-binding transcription factor activity, RNA polymerase II-specific

IBA

6 references

8 April 2019

A census of human transcription factors: function, expression and evolution

Norwegian University of Science and Technology, Systems Biology team

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q06413

8 April 2019

The MADS box transcription factor MEF2C regulates melanocyte development and is a direct transcriptional target and partner of SOX10

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q06413

8 April 2019

A census of human transcription factors: function, expression and evolution

Norwegian University of Science and Technology, Systems Biology team

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q06413

8 April 2019

Norwegian University of Science and Technology, Systems Biology team

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q06413

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q06413

8 April 2019

hMEF2C gene encodes skeletal muscle- and brain-specific transcription factors

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q06413

7 references

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q06413

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q06413

8 April 2019

hMEF2C gene encodes skeletal muscle- and brain-specific transcription factors

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q06413

8 April 2019

Inhibition of myogenesis by transforming growth factor beta is density-dependent and related to the translocation of transcription factor MEF2 to the cytoplasm

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q06413

8 April 2019

The Notch coactivator, MAML1, functions as a novel coactivator for MEF2C-mediated transcription and is required for normal myogenesis

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q06413

8 April 2019

MicroRNA-21 dysregulates the expression of MEF2C in neurons in monkey and human SIV/HIV neurological disease

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q06413

8 April 2019

MEF2C exon α: role in gene activation and differentiation

Alzheimers Project at University of Toronto

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q06413

1 reference

8 April 2019

MEF2C is activated by multiple mechanisms in a subset of T-acute lymphoblastic leukemia cell lines

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q06413

intracellular membrane-bounded organelle

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q06413

2 references

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q06413

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q06413

1 reference

8 April 2019

Gene Ontology Consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q06413

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q06413

protein-containing complex

1 reference

8 April 2019

Cooperative activation of atrial naturetic peptide promoter by dHAND and MEF2C

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q06413

embryonic skeletal system morphogenesis

biological process

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q06413

hMEF2C gene encodes skeletal muscle- and brain-specific transcription factors

myotube differentiation

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q06413

positive regulation of skeletal muscle tissue development

IEP

1 reference

8 April 2019

Inhibition of myogenesis by transforming growth factor beta is density-dependent and related to the translocation of transcription factor MEF2 to the cytoplasm

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q06413

positive regulation of muscle cell differentiation

IMP

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q06413

hMEF2C gene encodes skeletal muscle- and brain-specific transcription factors

TAS

muscle organ development

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q06413

TAS

monocyte differentiation

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q06413

negative regulation of ossification

1 reference

8 April 2019

Control of the SOST bone enhancer by PTH using MEF2 transcription factors

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q06413

positive regulation of skeletal muscle cell differentiation

1 reference

8 April 2019

Skeletal myosin light chain kinase regulates skeletal myogenesis by phosphorylation of MEF2C

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q06413

negative regulation of epithelial cell proliferation

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q06413

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q06413

cellular response to transforming growth factor beta stimulus

1 reference

8 April 2019

Inhibition of myogenesis by transforming growth factor beta is density-dependent and related to the translocation of transcription factor MEF2 to the cytoplasm

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q06413

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q06413

cardiac muscle cell differentiation

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q06413

transcription, DNA-templated

1 reference

5 June 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q06413&geneProductId=UniProtKB:Q06413

4 references

8 April 2019

Cooperative activation of atrial naturetic peptide promoter by dHAND and MEF2C

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q06413

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q06413

8 April 2019

Expression of MEF2 genes during human cardiac development

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q06413

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q06413

cardiac muscle hypertrophy in response to stress

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q06413

cellular response to parathyroid hormone stimulus

1 reference

8 April 2019

Control of the SOST bone enhancer by PTH using MEF2 transcription factors

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q06413

roof of mouth development

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q06413

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q06413

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q06413

neuron differentiation

3 references

8 April 2019

8 April 2019

hMEF2C gene encodes skeletal muscle- and brain-specific transcription factors

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q06413

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q06413

regulation of sarcomere organization

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q06413

skeletal muscle cell differentiation

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q06413

positive regulation of cell proliferation in bone marrow

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q06413

3 references

8 April 2019

Smad proteins function as co-modulators for MEF2 transcriptional regulatory proteins

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q06413

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q06413

8 April 2019

Regulation of the MEF2 family of transcription factors by p38

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q06413

multicellular organism development

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q06413

positive regulation of gene expression

3 references

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q06413

8 April 2019

Myocyte enhancer factor 2C and Nkx2-5 up-regulate each other's expression and initiate cardiomyogenesis in P19 cells

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q06413

8 April 2019

Skeletal myosin light chain kinase regulates skeletal myogenesis by phosphorylation of MEF2C

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q06413

positive regulation of myoblast differentiation

1 reference

8 April 2019

Inhibition of myogenesis by transforming growth factor beta is density-dependent and related to the translocation of transcription factor MEF2 to the cytoplasm

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q06413

IMP

cartilage morphogenesis

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q06413

embryonic viscerocranium morphogenesis

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q06413

positive regulation of transcription by RNA polymerase II

7 references

8 April 2019

Smad proteins function as co-modulators for MEF2 transcriptional regulatory proteins

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q06413

8 April 2019

Skeletal myosin light chain kinase regulates skeletal myogenesis by phosphorylation of MEF2C

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q06413

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q06413

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q06413

8 April 2019

hMEF2C gene encodes skeletal muscle- and brain-specific transcription factors

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q06413

8 April 2019

Cooperative activation of atrial naturetic peptide promoter by dHAND and MEF2C

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q06413

8 April 2019

MEF2-dependent recruitment of the HAND1 transcription factor results in synergistic activation of target promoters

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q06413

transcription by RNA polymerase II

1 reference

7 November 2018

Gene Ontology Consortium

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q06413&geneProductId=UniProtKB:Q06413

negative regulation of blood vessel endothelial cell migration

1 reference

8 April 2019

MiR-135b-5p and MiR-499a-3p Promote Cell Proliferation and Migration in Atherosclerosis by Directly Targeting MEF2C.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q06413

negative regulation of vascular associated smooth muscle cell proliferation

1 reference

27 March 2018

MiR-135b-5p and MiR-499a-3p Promote Cell Proliferation and Migration in Atherosclerosis by Directly Targeting MEF2C.

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q06413&geneProductId=UniProtKB:Q06413

negative regulation of vascular associated smooth muscle cell migration

1 reference

27 March 2018

MiR-135b-5p and MiR-499a-3p Promote Cell Proliferation and Migration in Atherosclerosis by Directly Targeting MEF2C.

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q06413&geneProductId=UniProtKB:Q06413

negative regulation of vascular endothelial cell proliferation

1 reference

8 April 2019

MiR-135b-5p and MiR-499a-3p Promote Cell Proliferation and Migration in Atherosclerosis by Directly Targeting MEF2C.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q06413

negative regulation of vascular associated smooth muscle cell proliferation

negative regulation of vascular associated smooth muscle cell migration

Holliday junction regulator protein family C-terminal

1 reference

Transcription factor, MADS-box

1 reference

MADS MEF2-like

1 reference