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Pellino E3 ubiquitin protein ligase family member 2
mammalian protein found in Homo sapiens
protein pellino homolog 2
pellino-2
RING-type E3 ubiquitin transferase pellino homolog 2
pellino homolog 2
PELI2
E3 ubiquitin-protein ligase pellino homolog 2
In more languages
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Statements
instance of
protein
1 reference
stated in
UniProt
retrieved
13 November 2019
UniProt protein ID
Q9HAT8
part of
Pellino family
1 reference
stated in
InterPro Release 71.0
reference URL
http://www.ebi.ac.uk/interpro/protein/Q9HAT8
found in taxon
Homo sapiens
1 reference
stated in
UniProt
retrieved
13 November 2019
UniProt protein ID
Q9HAT8
encoded by
PELI2
1 reference
stated in
UniProt
retrieved
13 November 2019
UniProt protein ID
Q9HAT8
molecular function
protein binding
determination method
IPI
3 references
retrieved
8 April 2019
stated in
Characterization of Pellino2, a substrate of IRAK1 and IRAK4
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9HAT8
determination method
IPI
retrieved
8 April 2019
stated in
Pellino Proteins Contain a Cryptic FHA Domain that Mediates Interaction with Phosphorylated IRAK1
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9HAT8
determination method
IPI
retrieved
8 April 2019
stated in
Pellino proteins are more than scaffold proteins in TLR/IL-1R signalling: a role as novel RING E3-ubiquitin-ligases
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9HAT8
determination method
IPI
ubiquitin-ubiquitin ligase activity
determination method
TAS
1 reference
retrieved
8 April 2019
stated in
GOA
curator
Reactome
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9HAT8
determination method
TAS
protein serine/threonine kinase activity
determination method
TAS
1 reference
retrieved
10 September 2018
stated in
GOA
curator
Reactome
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9HAT8&geneProductId=UniProtKB:Q9HAT8
determination method
TAS
transferase activity
determination method
IEA
1 reference
retrieved
8 April 2019
stated in
GOA
curator
UniProt
UniProt protein ID
Q9HAT8
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9HAT8
determination method
IEA
ubiquitin protein ligase activity
determination method
IBA
1 reference
retrieved
10 September 2018
stated in
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
GOA
curator
GO Central
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9HAT8&geneProductId=UniProtKB:Q9HAT8
determination method
IBA
ubiquitin protein ligase activity
determination method
IBA
IEA
2 references
retrieved
8 April 2019
stated in
GOA
curator
InterPro
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9HAT8
determination method
IEA
retrieved
8 April 2019
stated in
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
GOA
curator
GO Central
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9HAT8
determination method
IBA
cell component
cytosol
determination method
TAS
1 reference
retrieved
8 April 2019
stated in
GOA
curator
Reactome
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9HAT8
determination method
TAS
biological process
positive regulation of I-kappaB kinase/NF-kappaB signaling
determination method
TAS
1 reference
retrieved
8 April 2019
stated in
GOA
curator
Reactome
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9HAT8
determination method
TAS
positive regulation of protein phosphorylation
determination method
IDA
1 reference
retrieved
8 April 2019
stated in
Pellino2 activates the mitogen activated protein kinase pathway
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9HAT8
determination method
IDA
protein ubiquitination
determination method
IEA
1 reference
retrieved
8 April 2019
stated in
GOA
curator
UniProt
UniProt protein ID
Q9HAT8
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9HAT8
determination method
IEA
positive regulation of MAPK cascade
determination method
IDA
1 reference
retrieved
8 April 2019
stated in
Pellino2 activates the mitogen activated protein kinase pathway
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9HAT8
determination method
IDA
protein polyubiquitination
determination method
IBA
1 reference
retrieved
10 September 2018
stated in
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
GOA
curator
GO Central
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9HAT8&geneProductId=UniProtKB:Q9HAT8
determination method
IBA
protein phosphorylation
determination method
IEA
1 reference
retrieved
10 September 2018
stated in
GOA
curator
Gene Ontology Consortium
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9HAT8&geneProductId=UniProtKB:Q9HAT8
determination method
IEA
immune response
determination method
IBA
1 reference
retrieved
31 January 2018
stated in
GOA
curator
GO Central
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9HAT8&geneProductId=UniProtKB:Q9HAT8
determination method
IBA
Toll signaling pathway
determination method
IBA
IEA
2 references
retrieved
10 September 2018
stated in
GOA
curator
InterPro
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9HAT8&geneProductId=UniProtKB:Q9HAT8
determination method
IEA
retrieved
10 September 2018
stated in
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
GOA
curator
GO Central
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9HAT8&geneProductId=UniProtKB:Q9HAT8
determination method
IBA
interleukin-1-mediated signaling pathway
determination method
TAS
1 reference
retrieved
8 April 2019
stated in
GOA
curator
Reactome
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9HAT8
determination method
TAS
protein polyubiquitination
determination method
IBA
IEA
2 references
retrieved
8 April 2019
stated in
GOA
curator
InterPro
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9HAT8
determination method
IEA
retrieved
8 April 2019
stated in
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
GOA
curator
GO Central
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9HAT8
determination method
IBA
Toll signaling pathway
determination method
IBA
1 reference
retrieved
8 April 2019
stated in
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
GOA
curator
GO Central
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9HAT8
determination method
IBA
regulation of Toll signaling pathway
determination method
IEA
1 reference
retrieved
8 April 2019
stated in
GOA
curator
InterPro
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9HAT8
determination method
IEA
exact match
https://identifiers.org/uniprot:Q9HAT8
1 reference
stated in
Identifiers.org
UniProt protein ID
Q9HAT8
reference URL
https://registry.identifiers.org/registry/uniprot
http://purl.uniprot.org/uniprot/Q9HAT8
1 reference
stated in
Identifiers.org
UniProt protein ID
Q9HAT8
reference URL
https://registry.identifiers.org/registry/uniprot
https://www.ncbi.nlm.nih.gov/protein/Q9HAT8
1 reference
stated in
Identifiers.org
UniProt protein ID
Q9HAT8
reference URL
https://registry.identifiers.org/registry/uniprot
Identifiers
RefSeq protein ID
NP_067078
1 reference
stated in
NCBI Gene
retrieved
30 May 2020
Entrez Gene ID
57161
XP_005267947
1 reference
stated in
NCBI Gene
retrieved
30 May 2020
Entrez Gene ID
57161
XP_006720274
1 reference
stated in
NCBI Gene
retrieved
30 May 2020
Entrez Gene ID
57161
XP_011535292
1 reference
stated in
NCBI Gene
retrieved
30 May 2020
Entrez Gene ID
57161
XP_011535294
1 reference
stated in
NCBI Gene
retrieved
30 May 2020
Entrez Gene ID
57161
XP_016876967
1 reference
stated in
NCBI Gene
retrieved
30 May 2020
Entrez Gene ID
57161
XP_016876968
1 reference
stated in
NCBI Gene
retrieved
30 May 2020
Entrez Gene ID
57161
UniProt protein ID
Q9HAT8
1 reference
stated in
UniProt
retrieved
13 November 2019
UniProt protein ID
Q9HAT8
Ensembl protein ID
ENSP00000267460
1 reference
stated in
Ensembl Release 99
Ensembl protein ID
ENSP00000267460
ENSP00000452666
1 reference
stated in
Ensembl Release 99
Ensembl protein ID
ENSP00000452666
ENSP00000453988
1 reference
stated in
Ensembl Release 99
Ensembl protein ID
ENSP00000453988
PDB structure ID
3EGA
1 reference
stated in
UniProt
UniProt protein ID
Q9HAT8
retrieved
9 August 2016
language of work or name
English
3EGB
1 reference
stated in
UniProt
UniProt protein ID
Q9HAT8
retrieved
9 August 2016
language of work or name
English
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