(Q21119377)

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8NFZ5

8 April 2019

Integrative analysis of kinase networks in TRAIL-induced apoptosis provides a source of potential targets for combination therapy

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8NFZ5

8 April 2019

The A20-binding protein ABIN-2 exerts unexpected function in mediating transcriptional coactivation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8NFZ5

8 April 2019

A physical and functional map of the human TNF-alpha/NF-kappa B signal transduction pathway

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8NFZ5

8 April 2019

The inhibitor ABIN-2 disrupts the interaction of receptor-interacting protein with the kinase subunit IKKgamma to block activation of the transcription factor NF-kappaB and potentiate apoptosis

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8NFZ5

8 April 2019

A protein-protein interaction map of the TNF-induced NF-κB signal transduction pathway

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8NFZ5

8 April 2019

Proteomic analyses reveal distinct chromatin-associated and soluble transcription factor complexes

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8NFZ5

8 April 2019

ABIN-2 forms a ternary complex with TPL-2 and NF-kappa B1 p105 and is essential for TPL-2 protein stability

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8NFZ5

8 April 2019

Toward an understanding of the protein interaction network of the human liver

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8NFZ5

8 April 2019

A20 is a potent inhibitor of TLR3- and Sendai virus-induced activation of NF-kappaB and ISRE and IFN-beta promoter

British Heart Foundation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8NFZ5

A20-binding inhibitor of nuclear factor-kappaB (NF-kappaB)-2 (ABIN-2) is an activator of inhibitor of NF-kappaB (IkappaB) kinase alpha (IKKalpha)-mediated NF-kappaB transcriptional activity

IPI

protein kinase binding

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8NFZ5

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8NFZ5

polyubiquitin modification-dependent protein binding

1 reference

8 April 2019

Ubiquitin binding mediates the NF-kappaB inhibitory potential of ABIN proteins

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8NFZ5

K63-linked polyubiquitin modification-dependent protein binding

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8NFZ5

2 references

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8NFZ5

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8NFZ5

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8NFZ5

negative regulation of endothelial cell apoptotic process

biological process

1 reference

8 April 2019

ABIN-2 protects endothelial cells from death and has a role in the antiapoptotic effect of angiopoietin-1

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8NFZ5

regulation of transcription, DNA-templated

1 reference

27 February 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q8NFZ5&geneProductId=UniProtKB:Q8NFZ5

transcription, DNA-templated

1 reference

27 February 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q8NFZ5&geneProductId=UniProtKB:Q8NFZ5

stress-activated MAPK cascade

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8NFZ5

positive regulation of I-kappaB kinase/NF-kappaB signaling

TAS

1 reference

8 April 2019

A20-binding inhibitor of nuclear factor-kappaB (NF-kappaB)-2 (ABIN-2) is an activator of inhibitor of NF-kappaB (IkappaB) kinase alpha (IKKalpha)-mediated NF-kappaB transcriptional activity

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8NFZ5

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8NFZ5

inflammatory response

1 reference

8 April 2019

I-kappaB kinase/NF-kappaB signaling

1 reference

8 April 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8NFZ5

positive regulation of transcription by RNA polymerase II

1 reference

8 April 2019

The A20-binding protein ABIN-2 exerts unexpected function in mediating transcriptional coactivation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8NFZ5

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8NFZ5

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8NFZ5

protein deubiquitination

1 reference

8 April 2019

cellular response to lipopolysaccharide

TAS

interleukin-1-mediated signaling pathway

TSG101 and ALIX binding domain of CEP55

1 reference

stated in

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/Q8NFZ5

NEMO, Zinc finger

1 reference

stated in

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/Q8NFZ5

NF-kappa-B essential modulator NEMO, CC2-LZ domain

1 reference

stated in

InterPro Release 71.0