(Q21119704)

English

Phosphodiesterase 11A

mammalian protein found in Homo sapiens

dual 3',5'-cyclic-AMP and -GMP phosphodiesterase 11A
cAMP and cGMP phosphodiesterase 11A
cAMP and cGMP cyclic nucleotide phosphodiesterase 11A
PDE11A

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Statements

1 reference

13 November 2019

3'5'-cyclic nucleotide phosphodiesterase

1 reference

stated in

InterPro Release 71.0

reference URL

http://www.ebi.ac.uk/interpro/protein/Q9HCR9

3'5'-cyclic nucleotide phosphodiesterase, catalytic domain superfamily

1 reference

stated in

InterPro Release 71.0

reference URL

http://www.ebi.ac.uk/interpro/protein/Q9HCR9

GAF-like domain superfamily

1 reference

stated in

InterPro Release 71.0

reference URL

http://www.ebi.ac.uk/interpro/protein/Q9HCR9

3'5'-cyclic nucleotide phosphodiesterase, catalytic domain, protein family

1 reference

based on heuristic

inferred from protein domain or family

HD/PDEase domain, protein family

1 reference

based on heuristic

inferred from protein domain or family

GAF domain, protein family

1 reference

based on heuristic

inferred from protein domain or family

3'5'-cyclic nucleotide phosphodiesterase, conserved site, protein family

1 reference

based on heuristic

inferred from protein domain or family

1 reference

13 November 2019

1 reference

13 November 2019

phosphoric diester hydrolase activity

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9HCR9

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9HCR9

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9HCR9

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9HCR9

determination method

IEA

cGMP-stimulated cyclic-nucleotide phosphodiesterase activity

1 reference

16 July 2018

Binding of cyclic nucleotides to phosphodiesterase 10A and 11A GAF domains does not stimulate catalytic activity

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9HCR9&geneProductId=UniProtKB:Q9HCR9

determination method

IDA

3',5'-cyclic-AMP phosphodiesterase activity

1 reference

7 November 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9HCR9&geneProductId=UniProtKB:Q9HCR9

determination method

TAS

cyclic-nucleotide phosphodiesterase activity

1 reference

8 April 2019

Isolation and characterization of two novel phosphodiesterase PDE11A variants showing unique structure and tissue-specific expression

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9HCR9

1 reference

16 July 2018

Binding of cyclic nucleotides to phosphodiesterase 10A and 11A GAF domains does not stimulate catalytic activity

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9HCR9&geneProductId=UniProtKB:Q9HCR9

determination method

IDA

cGMP-stimulated cyclic-nucleotide phosphodiesterase activity

determination method

IBA

IDA

3',5'-cyclic-GMP phosphodiesterase activity

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9HCR9

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9HCR9

2 references

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9HCR9

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9HCR9

determination method

IEA

G protein-coupled receptor signaling pathway

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9HCR9

determination method

TAS

negative regulation of cGMP-mediated signaling

1 reference

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9HCR9

determination method

IBA

negative regulation of cAMP-mediated signaling

1 reference

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9HCR9

determination method

IBA

physically interacts with

1 reference

IUPHAR/BPS Guide to PHARMACOLOGY

Guide to Pharmacology Ligand ID

7299

language of work or name

English

retrieved

17 August 2016

Identifiers

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

13 November 2019

1 reference

1 reference

1 reference

1 reference

1 reference

1 reference

1 reference

(Q21119704)

Phosphodiesterase 11A

Statements

Identifiers

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