(Q21119706)

http://www.ebi.ac.uk/interpro/protein/Q9Y233

3'5'-cyclic nucleotide phosphodiesterase, catalytic domain superfamily

1 reference

stated in

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/Q9Y233

GAF-like domain superfamily

1 reference

stated in

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/Q9Y233

3'5'-cyclic nucleotide phosphodiesterase, catalytic domain, protein family

1 reference

HD/PDEase domain, protein family

1 reference

GAF domain, protein family

1 reference

3'5'-cyclic nucleotide phosphodiesterase, conserved site, protein family

1 reference

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Y233

1 reference

18 July 2018

1 reference

18 July 2018

1 reference

8 April 2019

3',5'-cyclic-nucleotide phosphodiesterase activity

4 references

21 June 2018

Cloning and characterization of a novel human phosphodiesterase that hydrolyzes both cAMP and cGMP (PDE10A)

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9Y233&geneProductId=UniProtKB:Q9Y233

21 June 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9Y233&geneProductId=UniProtKB:Q9Y233

21 June 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9Y233&geneProductId=UniProtKB:Q9Y233

21 June 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9Y233&geneProductId=UniProtKB:Q9Y233

3 references

21 June 2018

Structural determinants for inhibitor specificity and selectivity in PDE2A using the wheat germ in vitro translation system

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9Y233&geneProductId=UniProtKB:Q9Y233

21 June 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9Y233&geneProductId=UniProtKB:Q9Y233

21 June 2018

Binding of cyclic nucleotides to phosphodiesterase 10A and 11A GAF domains does not stimulate catalytic activity

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9Y233&geneProductId=UniProtKB:Q9Y233

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Y233

cGMP-stimulated cyclic-nucleotide phosphodiesterase activity

1 reference

21 June 2018

Binding of cyclic nucleotides to phosphodiesterase 10A and 11A GAF domains does not stimulate catalytic activity

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9Y233&geneProductId=UniProtKB:Q9Y233

cyclic-nucleotide phosphodiesterase activity

IDA

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Y233

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Y233

phosphoric diester hydrolase activity

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Y233

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Y233

3',5'-cyclic-AMP phosphodiesterase activity

1 reference

7 November 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9Y233&geneProductId=UniProtKB:Q9Y233

3',5'-cyclic-nucleotide phosphodiesterase activity

TAS

5 references

8 April 2019

Cloning and characterization of a novel human phosphodiesterase that hydrolyzes both cAMP and cGMP (PDE10A)

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Y233

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Y233

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Y233

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Y233

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Y233

cGMP-stimulated cyclic-nucleotide phosphodiesterase activity

IBA

4 references

8 April 2019

Structural determinants for inhibitor specificity and selectivity in PDE2A using the wheat germ in vitro translation system

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Y233

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Y233

8 April 2019

Binding of cyclic nucleotides to phosphodiesterase 10A and 11A GAF domains does not stimulate catalytic activity

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Y233

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Y233

3',5'-cyclic-GMP phosphodiesterase activity

IBA

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Y233

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Y233

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Y233

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Y233

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Y233

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Y233

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Y233

biological process

cAMP catabolic process

1 reference

8 April 2019

regulation of protein kinase A signaling

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Y233

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Y233

cGMP catabolic process

1 reference

8 April 2019

regulation of cAMP-mediated signaling

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Y233

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Y233

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Y233

G protein-coupled receptor signaling pathway

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Y233

negative regulation of cGMP-mediated signaling

TAS

1 reference

21 June 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9Y233&geneProductId=UniProtKB:Q9Y233

negative regulation of cAMP-mediated signaling

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Y233

physically interacts with

1 reference

Open Targets Platform

retrieved

14 August 2023

https://platform.opentargets.org/drug/CHEMBL19449

Identifiers

1 reference

18 May 2018

1 reference

18 May 2018

1 reference

18 May 2018

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18 May 2018

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18 May 2018

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18 May 2018

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18 May 2018

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18 May 2018

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18 May 2018

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18 May 2018

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6 April 2018

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6 April 2018

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18 July 2018

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9 August 2016

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9 August 2016