(Q21120415)

English

PAXX non-homologous end joining factor

mammalian protein found in Homo sapiens

XRCC4-like small protein
PAXX
C9orf142
protein PAXX
paralog of XRCC4 and XLF

In more languages

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Statements

1 reference

13 November 2019

1 reference

InterPro Release 71.0

reference URL

http://www.ebi.ac.uk/interpro/protein/Q9BUH6

1 reference

13 November 2019

1 reference

13 November 2019

molecular adaptor activity

1 reference

9 May 2019

DNA repair. PAXX, a paralog of XRCC4 and XLF, interacts with Ku to promote DNA double-strand break repair

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9BUH6

determination method

IPI

protein homodimerization activity

1 reference

9 May 2019

DNA repair. PAXX, a paralog of XRCC4 and XLF, interacts with Ku to promote DNA double-strand break repair

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9BUH6

determination method

IDA

identical protein binding

1 reference

27 March 2018

DNA repair. PAXX, a paralog of XRCC4 and XLF, interacts with Ku to promote DNA double-strand break repair

GOA

curator

IntAct protein interaction database

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9BUH6&geneProductId=UniProtKB:Q9BUH6

determination method

IPI

cell component

site of double-strand break

1 reference

8 April 2019

Interactome analysis identifies a new paralogue of XRCC4 in non-homologous end joining DNA repair pathway

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9BUH6

1 reference

9 May 2019

Interactome analysis identifies a new paralogue of XRCC4 in non-homologous end joining DNA repair pathway

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9BUH6

3 references

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9BUH6

8 April 2019

DNA repair. PAXX, a paralog of XRCC4 and XLF, interacts with Ku to promote DNA double-strand break repair

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9BUH6

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9BUH6

4 references

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9BUH6

9 May 2019

DNA repair. PAXX, a paralog of XRCC4 and XLF, interacts with Ku to promote DNA double-strand break repair

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9BUH6

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9BUH6

9 May 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9BUH6

determination method

IBA

nonhomologous end joining complex

3 references

9 May 2019

Interactome analysis identifies a new paralogue of XRCC4 in non-homologous end joining DNA repair pathway

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9BUH6

9 May 2019

XLS (c9orf142) is a new component of mammalian DNA double-stranded break repair

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9BUH6

9 May 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9BUH6

determination method

IBA

biological process

DNA ligation involved in DNA repair

1 reference

8 April 2019

DNA repair. PAXX, a paralog of XRCC4 and XLF, interacts with Ku to promote DNA double-strand break repair

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9BUH6

determination method

IMP

double-strand break repair via nonhomologous end joining

4 references

8 April 2019

Interactome analysis identifies a new paralogue of XRCC4 in non-homologous end joining DNA repair pathway

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9BUH6

8 April 2019

DNA repair. PAXX, a paralog of XRCC4 and XLF, interacts with Ku to promote DNA double-strand break repair

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9BUH6

8 April 2019

XLS (c9orf142) is a new component of mammalian DNA double-stranded break repair

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9BUH6

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9BUH6

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9BUH6

determination method

IEA

double-strand break repair via nonhomologous end joining

5 references

9 May 2019

Interactome analysis identifies a new paralogue of XRCC4 in non-homologous end joining DNA repair pathway

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9BUH6

9 May 2019

XLS (c9orf142) is a new component of mammalian DNA double-stranded break repair

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9BUH6

9 May 2019

DNA repair. PAXX, a paralog of XRCC4 and XLF, interacts with Ku to promote DNA double-strand break repair

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9BUH6

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9BUH6

9 May 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9BUH6

determination method

IBA

Identifiers

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

13 November 2019

1 reference

1 reference

21 March 2016

language of work or name

1 reference

21 March 2016

language of work or name

1 reference

21 March 2016

language of work or name

English

(Q21120415)

PAXX non-homologous end joining factor

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