(Q21120562)

English

ElaC ribonuclease Z 2

mammalian protein found in Homo sapiens

tRNA 3 endonuclease 2
zinc phosphodiesterase ELAC protein 2
elaC homolog 2
heredity prostate cancer protein 2
tRNase Z (long form)
RNase Z 2
ELAC2
elaC-like protein 2
elaC homolog protein 2
ribonuclease Z 2
putative prostate cancer susceptibility protein HPC2/ELAC2
tRNase Z 2

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Statements

1 reference

13 November 2019

Ribonuclease Z/Hydroxyacylglutathione hydrolase-like

1 reference

stated in

InterPro Release 71.0

reference URL

http://www.ebi.ac.uk/interpro/protein/Q9BQ52

Metallo-beta-lactamase domain, protein family

1 reference

based on heuristic

inferred from protein domain or family

tRNase Z endonuclease family

1 reference

based on heuristic

inferred from protein domain or family

1 reference

13 November 2019

1 reference

13 November 2019

endonuclease activity

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9BQ52

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9BQ52

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9BQ52

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9BQ52

determination method

IEA

tRNA-specific ribonuclease activity

6 references

8 April 2019

Localization of human RNase Z isoforms: dual nuclear/mitochondrial targeting of the ELAC2 gene product by alternative translation initiation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9BQ52

8 April 2019

Involvement of human ELAC2 gene product in 3' end processing of mitochondrial tRNAs

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9BQ52

8 April 2019

A candidate prostate cancer susceptibility gene encodes tRNA 3' processing endoribonuclease

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9BQ52

8 April 2019

The N-terminal half-domain of the long form of tRNase Z is required for the RNase 65 activity

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9BQ52

8 April 2019

Naturally occurring mutations in human mitochondrial pre-tRNASer(UCN) can affect the transfer ribonuclease Z cleavage site, processing kinetics, and substrate secondary structure

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9BQ52

8 April 2019

Functional analyses for tRNase Z variants: an aspartate and a histidine in the active site are essential for the catalytic activity

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9BQ52

determination method

EXP

3'-tRNA processing endoribonuclease activity

1 reference

26 September 2017

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9BQ52&geneProductId=UniProtKB:Q9BQ52

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9BQ52

determination method

TAS

mitochondrial nucleoid

1 reference

8 April 2019

Ensembl genome database project

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9BQ52

3 references

26 September 2017

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9BQ52&geneProductId=UniProtKB:Q9BQ52

26 September 2017

Ensembl genome database project

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9BQ52&geneProductId=UniProtKB:Q9BQ52

26 September 2017

Involvement of human ELAC2 gene product in 3' end processing of mitochondrial tRNAs

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9BQ52&geneProductId=UniProtKB:Q9BQ52

2 references

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9BQ52

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9BQ52

3 references

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9BQ52

8 April 2019

Involvement of human ELAC2 gene product in 3' end processing of mitochondrial tRNAs

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9BQ52

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9BQ52

determination method

IBA

biological process

mitochondrial tRNA 3'-trailer cleavage, endonucleolytic

1 reference

26 September 2017

Involvement of human ELAC2 gene product in 3' end processing of mitochondrial tRNAs

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9BQ52&geneProductId=UniProtKB:Q9BQ52

determination method

IMP

mitochondrial tRNA processing

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9BQ52

determination method

TAS

tRNA 3'-end processing

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9BQ52

determination method

TAS

has part(s)

Metallo-beta-lactamase domain

1 reference

stated in

InterPro Release 71.0

reference URL

http://www.ebi.ac.uk/interpro/protein/Q9BQ52

tRNase Z endonuclease

1 reference

stated in

InterPro Release 71.0

reference URL

http://www.ebi.ac.uk/interpro/protein/Q9BQ52

Identifiers

1 reference

30 May 2020

1 reference

30 May 2020

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30 May 2020

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30 May 2020

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30 May 2020

1 reference

30 May 2020

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30 May 2020

1 reference

30 May 2020

1 reference

30 May 2020

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30 May 2020

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30 May 2020

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

13 November 2019

1 reference

1 reference

1 reference

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1 reference

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1 reference

1 reference

(Q21120562)

ElaC ribonuclease Z 2

Statements

Identifiers

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