(Q21120597)

http://www.ebi.ac.uk/interpro/protein/Q5TA89

Myc-type, basic helix-loop-helix (bHLH) domain, protein family

1 reference

based on heuristic

inferred from protein domain or family

Orange domain, protein family

1 reference

based on heuristic

inferred from protein domain or family

1 reference

13 November 2019

1 reference

13 November 2019

protein dimerization activity

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q5TA89

transcription factor binding

1 reference

9 May 2019

Integrative genomic analyses on HES/HEY family: Notch-independent HES1, HES3 transcription in undifferentiated ES cells, and Notch-dependent HES1, HES5, HEY1, HEY2, HEYL transcription in fetal tissues, adult tissues, or cancer

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q5TA89

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q5TA89

DNA-binding transcription repressor activity, RNA polymerase II-specific

4 references

27 March 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q5TA89&geneProductId=UniProtKB:Q5TA89

27 March 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q5TA89&geneProductId=UniProtKB:Q5TA89

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q5TA89

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q5TA89

double-stranded DNA binding

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q5TA89

RNA polymerase II transcription regulatory region sequence-specific DNA binding

1 reference

9 May 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q5TA89

DNA-binding transcription repressor activity, RNA polymerase II-specific

6 references

10 September 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q5TA89&geneProductId=UniProtKB:Q5TA89

10 September 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q5TA89&geneProductId=UniProtKB:Q5TA89

10 September 2018

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q5TA89&geneProductId=UniProtKB:Q5TA89

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q5TA89

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q5TA89

9 May 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q5TA89

transcription corepressor activity

1 reference

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q5TA89

transcription factor binding

sequence-specific DNA binding

NAS

1 reference

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q5TA89

sequence-specific double-stranded DNA binding

1 reference

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q5TA89

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q5TA89

1 reference

27 March 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q5TA89&geneProductId=UniProtKB:Q5TA89

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q5TA89

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q5TA89&geneProductId=UniProtKB:Q5TA89

ND

biological process

Notch signaling pathway

4 references

27 March 2018

27 March 2018

Notch signaling is required for maintaining stem-cell features of neuroprogenitor cells derived from human embryonic stem cells

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q5TA89&geneProductId=UniProtKB:Q5TA89

27 March 2018

Notch3 signaling promotes the development of pulmonary arterial hypertension

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q5TA89&geneProductId=UniProtKB:Q5TA89

27 March 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q5TA89&geneProductId=UniProtKB:Q5TA89

auditory receptor cell fate determination

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q5TA89

establishment of epithelial cell polarity

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q5TA89

1 reference

27 March 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q5TA89&geneProductId=UniProtKB:Q5TA89

regulation of inner ear auditory receptor cell differentiation

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q5TA89

regulation of transcription, DNA-templated

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q5TA89

inner ear receptor cell stereocilium organization

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q5TA89

comma-shaped body morphogenesis

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q5TA89

metanephric nephron tubule morphogenesis

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q5TA89

chondrocyte differentiation

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q5TA89

negative regulation of forebrain neuron differentiation

ISS

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q5TA89

transcription, DNA-templated

1 reference

27 March 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q5TA89&geneProductId=UniProtKB:Q5TA89

nervous system development

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q5TA89

negative regulation of stem cell differentiation

1 reference

9 May 2019

Notch signaling is required for maintaining stem-cell features of neuroprogenitor cells derived from human embryonic stem cells

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q5TA89

multicellular organism development

IMP

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q5TA89

forebrain radial glial cell differentiation

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q5TA89

S-shaped body morphogenesis

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q5TA89

neuron differentiation

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q5TA89

positive regulation of cell population proliferation

1 reference

9 May 2019

Notch activation promotes cell proliferation and the formation of neural stem cell-like colonies in human glioma cells

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q5TA89

specification of loop of Henle identity

IMP

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q5TA89

regulation of epithelial cell proliferation

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q5TA89

negative regulation of transcription, DNA-templated

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q5TA89

negative regulation of inner ear receptor cell differentiation

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q5TA89

positive regulation of Notch signaling pathway

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q5TA89

positive regulation of transcription by RNA polymerase II

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q5TA89

positive regulation of smooth muscle cell proliferation

1 reference

9 May 2019

Notch3 signaling promotes the development of pulmonary arterial hypertension

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q5TA89

1 reference

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q5TA89

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q5TA89

Notch signaling pathway

5 references

9 May 2019

9 May 2019

Notch3 signaling promotes the development of pulmonary arterial hypertension

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q5TA89

9 May 2019

Notch signaling is required for maintaining stem-cell features of neuroprogenitor cells derived from human embryonic stem cells

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q5TA89

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q5TA89

9 May 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q5TA89

regulation of neurogenesis

3 references

negative regulation of transcription by RNA polymerase II

3 references

central nervous system development

1 reference

9 May 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q5TA89

anterior/posterior pattern specification

1 reference

9 May 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q5TA89

inner ear auditory receptor cell differentiation

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q5TA89

negative regulation of inner ear auditory receptor cell differentiation

ISS

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q5TA89

negative regulation of neuron differentiation

3 references

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/Q5TA89

Myc-type, basic helix-loop-helix (bHLH) domain

1 reference

stated in

InterPro Release 71.0