Home
Random
Nearby
Log in
Settings
Donate
About Wikidata
Disclaimers
Search
(Q21120605)
Watch
English
Hes family bHLH transcription factor 4
mammalian protein found in Homo sapiens
transcription factor HES-4
HES4
class B basic helix-loop-helix protein 42
hHES4
bHLH factor Hes4
bHLHb42
hairy and enhancer of split 4
In more languages
edit
Statements
instance of
protein
1 reference
stated in
UniProt
retrieved
13 November 2019
UniProt protein ID
Q9HCC6
part of
Helix-loop-helix DNA-binding domain superfamily
1 reference
stated in
InterPro Release 71.0
reference URL
http://www.ebi.ac.uk/interpro/protein/Q9HCC6
Myc-type, basic helix-loop-helix (bHLH) domain, protein family
1 reference
based on heuristic
inferred from protein domain or family
Orange domain, protein family
1 reference
based on heuristic
inferred from protein domain or family
found in taxon
Homo sapiens
1 reference
stated in
UniProt
retrieved
13 November 2019
UniProt protein ID
Q9HCC6
encoded by
HES4
1 reference
stated in
UniProt
retrieved
13 November 2019
UniProt protein ID
Q9HCC6
molecular function
DNA binding
determination method
IEA
2 references
retrieved
9 May 2019
stated in
GOA
curator
UniProt
UniProt protein ID
Q9HCC6
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9HCC6
determination method
IEA
retrieved
9 May 2019
stated in
GOA
curator
InterPro
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9HCC6
determination method
IEA
transcription factor binding
determination method
NAS
1 reference
retrieved
9 May 2019
stated in
Integrative genomic analyses on HES/HEY family: Notch-independent HES1, HES3 transcription in undifferentiated ES cells, and Notch-dependent HES1, HES5, HEY1, HEY2, HEYL transcription in fetal tissues, adult tissues, or cancer
GOA
curator
UniProt
UniProt protein ID
Q9HCC6
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9HCC6
determination method
NAS
protein dimerization activity
determination method
IEA
1 reference
retrieved
9 May 2019
stated in
GOA
curator
InterPro
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9HCC6
determination method
IEA
DNA-binding transcription factor activity, RNA polymerase II-specific
determination method
ISA
ISM
2 references
retrieved
9 May 2019
stated in
A census of human transcription factors: function, expression and evolution
GOA
curator
Norwegian University of Science and Technology, Systems Biology team
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9HCC6
determination method
ISM
retrieved
9 May 2019
stated in
GOA
curator
Norwegian University of Science and Technology, Systems Biology team
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9HCC6
determination method
ISA
RNA polymerase II transcription regulatory region sequence-specific DNA binding
determination method
IBA
1 reference
retrieved
9 May 2019
stated in
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
GOA
curator
GO Central
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9HCC6
determination method
IBA
DNA-binding transcription repressor activity, RNA polymerase II-specific
determination method
IBA
2 references
retrieved
10 September 2018
stated in
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
GOA
curator
GO Central
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9HCC6&geneProductId=UniProtKB:Q9HCC6
determination method
IBA
retrieved
9 May 2019
stated in
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
GOA
curator
GO Central
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9HCC6
determination method
IBA
transcription corepressor activity
determination method
IBA
1 reference
retrieved
8 April 2019
stated in
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
GOA
curator
GO Central
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9HCC6
determination method
IBA
transcription factor binding
determination method
IBA
NAS
2 references
retrieved
8 April 2019
stated in
Integrative genomic analyses on HES/HEY family: Notch-independent HES1, HES3 transcription in undifferentiated ES cells, and Notch-dependent HES1, HES5, HEY1, HEY2, HEYL transcription in fetal tissues, adult tissues, or cancer
GOA
curator
UniProt
UniProt protein ID
Q9HCC6
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9HCC6
determination method
NAS
retrieved
8 April 2019
stated in
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
GOA
curator
GO Central
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9HCC6
determination method
IBA
sequence-specific DNA binding
determination method
IBA
1 reference
retrieved
8 April 2019
stated in
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
GOA
curator
GO Central
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9HCC6
determination method
IBA
sequence-specific double-stranded DNA binding
determination method
IBA
1 reference
retrieved
8 April 2019
stated in
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
GOA
curator
GO Central
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9HCC6
determination method
IBA
cell component
nucleus
determination method
IEA
1 reference
retrieved
27 March 2018
stated in
GOA
curator
UniProt
UniProt protein ID
Q9HCC6
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9HCC6&geneProductId=UniProtKB:Q9HCC6
determination method
IEA
nucleus
determination method
IBA
IEA
2 references
retrieved
9 May 2019
stated in
GOA
curator
UniProt
UniProt protein ID
Q9HCC6
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9HCC6
determination method
IEA
retrieved
9 May 2019
stated in
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
GOA
curator
GO Central
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9HCC6
determination method
IBA
biological process
multicellular organism development
determination method
IEA
1 reference
retrieved
9 May 2019
stated in
GOA
curator
UniProt
UniProt protein ID
Q9HCC6
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9HCC6
determination method
IEA
cell differentiation
determination method
IEA
1 reference
retrieved
27 March 2018
stated in
GOA
curator
UniProt
UniProt protein ID
Q9HCC6
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9HCC6&geneProductId=UniProtKB:Q9HCC6
determination method
IEA
regulation of transcription, DNA-templated
determination method
IEA
1 reference
retrieved
9 May 2019
stated in
GOA
curator
InterPro
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9HCC6
determination method
IEA
transcription, DNA-templated
determination method
IEA
1 reference
retrieved
27 March 2018
stated in
GOA
curator
UniProt
UniProt protein ID
Q9HCC6
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9HCC6&geneProductId=UniProtKB:Q9HCC6
determination method
IEA
nervous system development
determination method
IEA
1 reference
retrieved
9 May 2019
stated in
GOA
curator
UniProt
UniProt protein ID
Q9HCC6
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9HCC6
determination method
IEA
regulation of transcription by RNA polymerase II
determination method
IEA
1 reference
retrieved
8 April 2019
stated in
GOA
curator
Gene Ontology Consortium
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9HCC6
determination method
IEA
negative regulation of transcription by RNA polymerase II
determination method
IEA
1 reference
retrieved
7 November 2018
stated in
GOA
curator
Gene Ontology Consortium
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9HCC6&geneProductId=UniProtKB:Q9HCC6
determination method
IEA
somitogenesis
determination method
IBA
1 reference
retrieved
8 April 2019
stated in
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
GOA
curator
GO Central
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9HCC6
determination method
IBA
Notch signaling pathway
determination method
IBA
1 reference
retrieved
8 April 2019
stated in
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
GOA
curator
GO Central
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9HCC6
determination method
IBA
cell differentiation
determination method
IBA
IEA
2 references
retrieved
9 May 2019
stated in
GOA
curator
UniProt
UniProt protein ID
Q9HCC6
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9HCC6
determination method
IEA
retrieved
9 May 2019
stated in
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
GOA
curator
GO Central
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9HCC6
determination method
IBA
regulation of neurogenesis
determination method
IBA
1 reference
retrieved
8 April 2019
stated in
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
GOA
curator
GO Central
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9HCC6
determination method
IBA
negative regulation of nucleic acid-templated transcription
determination method
IEA
1 reference
retrieved
8 April 2019
stated in
GOA
curator
Gene Ontology Consortium
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9HCC6
determination method
IEA
negative regulation of transcription by RNA polymerase II
determination method
IBA
1 reference
retrieved
9 May 2019
stated in
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
GOA
curator
GO Central
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9HCC6
determination method
IBA
anterior/posterior pattern specification
determination method
IBA
1 reference
retrieved
9 May 2019
stated in
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
GOA
curator
GO Central
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9HCC6
determination method
IBA
negative regulation of neuron differentiation
determination method
IBA
1 reference
retrieved
9 May 2019
stated in
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
GOA
curator
GO Central
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9HCC6
determination method
IBA
has part(s)
Orange domain
1 reference
stated in
InterPro Release 71.0
reference URL
http://www.ebi.ac.uk/interpro/protein/Q9HCC6
Myc-type, basic helix-loop-helix (bHLH) domain
1 reference
stated in
InterPro Release 71.0
reference URL
http://www.ebi.ac.uk/interpro/protein/Q9HCC6
Identifiers
RefSeq protein ID
NP_001135939
1 reference
stated in
NCBI Gene
retrieved
30 May 2020
Entrez Gene ID
57801
NP_066993
1 reference
stated in
NCBI Gene
retrieved
30 May 2020
Entrez Gene ID
57801
XP_005244828
1 reference
stated in
NCBI Gene
retrieved
30 May 2020
Entrez Gene ID
57801
UniProt protein ID
Q9HCC6
1 reference
stated in
UniProt
retrieved
13 November 2019
UniProt protein ID
Q9HCC6
Ensembl protein ID
ENSP00000304595
1 reference
stated in
Ensembl Release 99
Ensembl protein ID
ENSP00000304595
ENSP00000393198
1 reference
stated in
Ensembl Release 99
Ensembl protein ID
ENSP00000393198
ENSP00000425085
1 reference
stated in
Ensembl Release 99
Ensembl protein ID
ENSP00000425085
Sitelinks
Wikipedia
(0 entries)
edit
Wikibooks
(0 entries)
edit
Wikinews
(0 entries)
edit
Wikiquote
(0 entries)
edit
Wikisource
(0 entries)
edit
Wikiversity
(0 entries)
edit
Wikivoyage
(0 entries)
edit
Wiktionary
(0 entries)
edit
Multilingual sites
(0 entries)
edit
