(Q21121002)

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/Q53GL7

PARP-10, RNA recognition motif 1 and 2, protein family

1 reference

based on heuristic

inferred from protein domain or family

Poly(ADP-ribose) polymerase, catalytic domain, protein family

1 reference

based on heuristic

inferred from protein domain or family

1 reference

13 November 2019

1 reference

13 November 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q53GL7

1 reference

8 April 2019

K63-linked polyubiquitin modification-dependent protein binding

1 reference

8 April 2019

Regulation of NF-κB signalling by the mono-ADP-ribosyltransferase ARTD10

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q53GL7

protein binding

5 references

8 April 2019

PARP-10, a novel Myc-interacting protein with poly(ADP-ribose) polymerase activity, inhibits transformation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q53GL7

8 April 2019

The ADP-ribosyltransferase PARP10/ARTD10 interacts with proliferating cell nuclear antigen (PCNA) and is required for DNA damage tolerance

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q53GL7

8 April 2019

Recognition of mono-ADP-ribosylated ARTD10 substrates by ARTD8 macrodomains

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q53GL7

8 April 2019

The interaction between the PARP10 protein and the NS1 protein of H5N1 AIV and its effect on virus replication

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q53GL7

8 April 2019

Deficiency of terminal ADP-ribose protein glycohydrolase TARG1/C6orf130 in neurodegenerative disease

GOA

curator

IntAct protein interaction database

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q53GL7

glycosyltransferase activity

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q53GL7

1 reference

8 April 2019

NAD+ ADP-ribosyltransferase activity

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q53GL7&geneProductId=UniProtKB:Q53GL7

4 references

1 January 2018

TAS

1 January 2018

Recognition of mono-ADP-ribosylated ARTD10 substrates by ARTD8 macrodomains

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q53GL7&geneProductId=UniProtKB:Q53GL7

1 January 2018

Regulation of NF-κB signalling by the mono-ADP-ribosyltransferase ARTD10

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q53GL7&geneProductId=UniProtKB:Q53GL7

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q53GL7&geneProductId=UniProtKB:Q53GL7

1 January 2018

protein ADP-ribosylase activity

The ADP-ribosyltransferase PARP10/ARTD10 interacts with proliferating cell nuclear antigen (PCNA) and is required for DNA damage tolerance

3 references

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q53GL7

8 April 2019

Family-wide analysis of poly(ADP-ribose) polymerase activity

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q53GL7

8 April 2019

Substrate-assisted catalysis by PARP10 limits its activity to mono-ADP-ribosylation.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q53GL7

NAD+ ADP-ribosyltransferase activity

Recognition of mono-ADP-ribosylated ARTD10 substrates by ARTD8 macrodomains

3 references

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q53GL7

8 April 2019

Regulation of NF-κB signalling by the mono-ADP-ribosyltransferase ARTD10

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q53GL7

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q53GL7

8 April 2019

cell component

cytoplasm

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q53GL7

4 references

8 April 2019

8 April 2019

PARP-10, a novel Myc-interacting protein with poly(ADP-ribose) polymerase activity, inhibits transformation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q53GL7

8 April 2019

Recognition of mono-ADP-ribosylated ARTD10 substrates by ARTD8 macrodomains

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q53GL7

8 April 2019

The interaction between the PARP10 protein and the NS1 protein of H5N1 AIV and its effect on virus replication

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q53GL7

nucleus

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q53GL7

4 references

8 April 2019

8 April 2019

PARP-10, a novel Myc-interacting protein with poly(ADP-ribose) polymerase activity, inhibits transformation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q53GL7

8 April 2019

Recognition of mono-ADP-ribosylated ARTD10 substrates by ARTD8 macrodomains

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q53GL7

8 April 2019

The interaction between the PARP10 protein and the NS1 protein of H5N1 AIV and its effect on virus replication

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q53GL7

intracellular membrane-bounded organelle

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q53GL7

1 reference

8 April 2019

negative regulation of protein K63-linked ubiquitination

biological process

1 reference

8 April 2019

Regulation of NF-κB signalling by the mono-ADP-ribosyltransferase ARTD10

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q53GL7

protein auto-ADP-ribosylation

1 reference

7 November 2018

Regulation of NF-κB signalling by the mono-ADP-ribosyltransferase ARTD10

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q53GL7&geneProductId=UniProtKB:Q53GL7

negative regulation of NF-kappaB transcription factor activity

1 reference

8 April 2019

Regulation of NF-κB signalling by the mono-ADP-ribosyltransferase ARTD10

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q53GL7

protein ADP-ribosylation

1 reference

8 April 2019

Regulation of NF-κB signalling by the mono-ADP-ribosyltransferase ARTD10

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q53GL7

negative regulation of fibroblast proliferation

1 reference

8 April 2019

PARP-10, a novel Myc-interacting protein with poly(ADP-ribose) polymerase activity, inhibits transformation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q53GL7

negative regulation of gene expression

1 reference

8 April 2019

Regulation of NF-κB signalling by the mono-ADP-ribosyltransferase ARTD10

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q53GL7

NAD biosynthesis via nicotinamide riboside salvage pathway

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q53GL7

1 reference

8 April 2019

protein poly-ADP-ribosylation

TAS

translesion synthesis

1 reference

8 April 2019

The ADP-ribosyltransferase PARP10/ARTD10 interacts with proliferating cell nuclear antigen (PCNA) and is required for DNA damage tolerance

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q53GL7

protein auto-ADP-ribosylation

Regulation of NF-κB signalling by the mono-ADP-ribosyltransferase ARTD10

3 references

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q53GL7

8 April 2019

Family-wide analysis of poly(ADP-ribose) polymerase activity

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q53GL7

8 April 2019

Substrate-assisted catalysis by PARP10 limits its activity to mono-ADP-ribosylation.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q53GL7

DNA repair

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q53GL7

1 reference

8 April 2019

cellular response to DNA damage stimulus

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q53GL7

1 reference

8 April 2019

poly(ADP-ribose) polymerase, catalytic domain

has part(s)

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/Q53GL7

PARP-10, RNA recognition motif 1 and 2

1 reference

InterPro Release 71.0