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(Q21121399)
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English
Sarcoglycan alpha
mammalian protein found in Homo sapiens
alpha-SG
alpha-sarcoglycan
dystroglycan-2
Adhalin
SGCA
50kD DAG
50DAG
sarcoglycan, alpha (50kDa dystrophin-associated glycoprotein)
limb girdle muscular dystrophy 2D
50 kDa dystrophin-associated glycoprotein
In more languages
edit
Statements
instance of
protein
1 reference
stated in
UniProt
retrieved
13 November 2019
UniProt protein ID
Q16586
part of
Cadherin-like superfamily
1 reference
stated in
InterPro Release 71.0
reference URL
http://www.ebi.ac.uk/interpro/protein/Q16586
Alpha-sarcoglycan
1 reference
stated in
InterPro Release 71.0
reference URL
http://www.ebi.ac.uk/interpro/protein/Q16586
Dystroglycan-type cadherin-like, protein family
1 reference
based on heuristic
inferred from protein domain or family
found in taxon
Homo sapiens
1 reference
stated in
UniProt
retrieved
13 November 2019
UniProt protein ID
Q16586
encoded by
SGCA
1 reference
stated in
UniProt
retrieved
13 November 2019
UniProt protein ID
Q16586
molecular function
calcium ion binding
determination method
IEA
1 reference
retrieved
8 April 2019
stated in
GOA
curator
InterPro
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q16586
determination method
IEA
protein binding
determination method
IPI
4 references
retrieved
8 April 2019
stated in
A proteome-scale map of the human interactome network
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q16586
determination method
IPI
retrieved
8 April 2019
stated in
Widespread macromolecular interaction perturbations in human genetic disorders
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q16586
determination method
IPI
retrieved
8 April 2019
stated in
Next-generation sequencing to generate interactome datasets
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q16586
determination method
IPI
retrieved
8 April 2019
stated in
Widespread Expansion of Protein Interaction Capabilities by Alternative Splicing
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q16586
determination method
IPI
protein binding
determination method
IBA
IPI
5 references
retrieved
7 November 2018
stated in
Widespread macromolecular interaction perturbations in human genetic disorders
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=Q16586&geneProductId=UniProtKB:Q16586
determination method
IPI
retrieved
7 November 2018
stated in
Widespread Expansion of Protein Interaction Capabilities by Alternative Splicing
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=Q16586&geneProductId=UniProtKB:Q16586
determination method
IPI
retrieved
7 November 2018
stated in
A proteome-scale map of the human interactome network
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=Q16586&geneProductId=UniProtKB:Q16586
determination method
IPI
retrieved
7 November 2018
stated in
Next-generation sequencing to generate interactome datasets
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=Q16586&geneProductId=UniProtKB:Q16586
determination method
IPI
retrieved
7 November 2018
stated in
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
GOA
curator
GO Central
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=Q16586&geneProductId=UniProtKB:Q16586
determination method
IBA
cell component
cytoplasm
determination method
IEA
1 reference
retrieved
8 April 2019
stated in
GOA
curator
UniProt
UniProt protein ID
Q16586
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q16586
determination method
IEA
integral component of membrane
determination method
IEA
1 reference
retrieved
8 April 2019
stated in
GOA
curator
UniProt
UniProt protein ID
Q16586
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q16586
determination method
IEA
membrane raft
determination method
IEA
1 reference
retrieved
8 April 2019
stated in
GOA
curator
Ensembl genome database project
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q16586
determination method
IEA
dystroglycan complex
determination method
IEA
1 reference
retrieved
8 April 2019
stated in
GOA
curator
Ensembl genome database project
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q16586
determination method
IEA
sarcolemma
determination method
IEA
2 references
retrieved
8 April 2019
stated in
GOA
curator
UniProt
UniProt protein ID
Q16586
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q16586
determination method
IEA
retrieved
8 April 2019
stated in
GOA
curator
Ensembl genome database project
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q16586
determination method
IEA
plasma membrane
determination method
IEA
2 references
retrieved
8 April 2019
stated in
GOA
curator
UniProt
UniProt protein ID
Q16586
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q16586
determination method
IEA
retrieved
8 April 2019
stated in
GOA
curator
Ensembl genome database project
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q16586
determination method
IEA
dystrophin-associated glycoprotein complex
determination method
TAS
1 reference
retrieved
8 April 2019
stated in
Human adhalin is alternatively spliced and the gene is located on chromosome 17q21
GOA
curator
Proteome Inc.
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q16586
determination method
TAS
cytoskeleton
determination method
IEA
1 reference
retrieved
8 April 2019
stated in
GOA
curator
UniProt
UniProt protein ID
Q16586
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q16586
determination method
IEA
membrane
determination method
IEA
2 references
retrieved
8 April 2019
stated in
GOA
curator
UniProt
UniProt protein ID
Q16586
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q16586
determination method
IEA
retrieved
8 April 2019
stated in
GOA
curator
InterPro
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q16586
determination method
IEA
cell-cell junction
determination method
IEA
1 reference
retrieved
8 April 2019
stated in
GOA
curator
Ensembl genome database project
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q16586
determination method
IEA
sarcoglycan complex
determination method
IEA
2 references
retrieved
7 November 2018
stated in
GOA
curator
InterPro
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=Q16586&geneProductId=UniProtKB:Q16586
determination method
IEA
retrieved
7 November 2018
stated in
GOA
curator
Ensembl genome database project
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=Q16586&geneProductId=UniProtKB:Q16586
determination method
IEA
sarcoglycan complex
determination method
IBA
IEA
3 references
retrieved
8 April 2019
stated in
GOA
curator
InterPro
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q16586
determination method
IEA
retrieved
8 April 2019
stated in
GOA
curator
Ensembl genome database project
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q16586
determination method
IEA
retrieved
8 April 2019
stated in
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
GOA
curator
GO Central
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q16586
determination method
IBA
biological process
muscle organ development
determination method
TAS
1 reference
retrieved
8 April 2019
stated in
Primary adhalinopathy: a common cause of autosomal recessive muscular dystrophy of variable severity
GOA
curator
Proteome Inc.
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q16586
determination method
TAS
muscle contraction
determination method
TAS
1 reference
retrieved
8 April 2019
stated in
Missense mutations in the adhalin gene linked to autosomal recessive muscular dystrophy
GOA
curator
Proteome Inc.
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q16586
determination method
TAS
membrane organization
determination method
IBA
1 reference
retrieved
16 July 2018
stated in
GOA
curator
GO Central
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=Q16586&geneProductId=UniProtKB:Q16586
determination method
IBA
response to denervation involved in regulation of muscle adaptation
determination method
IEA
1 reference
retrieved
8 April 2019
stated in
GOA
curator
Ensembl genome database project
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q16586
determination method
IEA
skeletal muscle tissue regeneration
determination method
IEA
1 reference
retrieved
8 April 2019
stated in
GOA
curator
Ensembl genome database project
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q16586
determination method
IEA
response to denervation involved in regulation of muscle adaptation
determination method
IBA
IEA
2 references
retrieved
7 November 2018
stated in
GOA
curator
Ensembl genome database project
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=Q16586&geneProductId=UniProtKB:Q16586
determination method
IEA
retrieved
7 November 2018
stated in
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
GOA
curator
GO Central
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=Q16586&geneProductId=UniProtKB:Q16586
determination method
IBA
skeletal muscle tissue regeneration
determination method
IBA
IEA
2 references
retrieved
7 November 2018
stated in
GOA
curator
Ensembl genome database project
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=Q16586&geneProductId=UniProtKB:Q16586
determination method
IEA
retrieved
7 November 2018
stated in
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
GOA
curator
GO Central
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=Q16586&geneProductId=UniProtKB:Q16586
determination method
IBA
has part(s)
Dystroglycan-type cadherin-like
1 reference
stated in
InterPro Release 71.0
reference URL
http://www.ebi.ac.uk/interpro/protein/Q16586
Identifiers
RefSeq protein ID
NP_000014
1 reference
stated in
NCBI Gene
retrieved
30 May 2020
Entrez Gene ID
6442
NP_001129169
1 reference
stated in
NCBI Gene
retrieved
30 May 2020
Entrez Gene ID
6442
XP_011523422
1 reference
stated in
NCBI Gene
retrieved
30 May 2020
Entrez Gene ID
6442
XP_011523423
1 reference
stated in
NCBI Gene
retrieved
30 May 2020
Entrez Gene ID
6442
XP_011523424
1 reference
stated in
NCBI Gene
retrieved
30 May 2020
Entrez Gene ID
6442
XP_011523425
1 reference
stated in
NCBI Gene
retrieved
30 May 2020
Entrez Gene ID
6442
XP_011523426
1 reference
stated in
NCBI Gene
retrieved
30 May 2020
Entrez Gene ID
6442
XP_024306641
1 reference
stated in
NCBI Gene
retrieved
30 May 2020
Entrez Gene ID
6442
UniProt protein ID
Q16586
1 reference
stated in
UniProt
retrieved
13 November 2019
UniProt protein ID
Q16586
Ensembl protein ID
ENSP00000262018
1 reference
stated in
Ensembl Release 99
Ensembl protein ID
ENSP00000262018
ENSP00000345522
1 reference
stated in
Ensembl Release 99
Ensembl protein ID
ENSP00000345522
ENSP00000422030
1 reference
stated in
Ensembl Release 99
Ensembl protein ID
ENSP00000422030
ENSP00000422817
1 reference
stated in
Ensembl Release 99
Ensembl protein ID
ENSP00000422817
ENSP00000423168
1 reference
stated in
Ensembl Release 99
Ensembl protein ID
ENSP00000423168
ENSP00000426104
1 reference
stated in
Ensembl Release 99
Ensembl protein ID
ENSP00000426104
ENSP00000426571
1 reference
stated in
Ensembl Release 99
Ensembl protein ID
ENSP00000426571
ENSP00000426606
1 reference
stated in
Ensembl Release 99
Ensembl protein ID
ENSP00000426606
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