(Q21121516)

Peptidase S1, PA clan

1 reference

Serine proteases, trypsin domain, protein family

1 reference

based on heuristic

inferred from protein domain or family

Serine proteases, trypsin family, histidine active site, protein family

1 reference

based on heuristic

inferred from protein domain or family

Serine proteases, trypsin family, serine active site, protein family

1 reference

based on heuristic

inferred from protein domain or family

1 reference

13 November 2019

1 reference

13 November 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P49862

1 reference

8 April 2019

serine-type endopeptidase activity

IEA

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P49862

1 reference

8 April 2019

metalloendopeptidase activity

IEA

http://www.ebi.ac.uk/QuickGO/annotations?protein=P49862&geneProductId=UniProtKB:P49862

1 reference

10 September 2018

cell component

epidermal lamellar body

IDA

1 reference

8 April 2019

LEKTI is localized in lamellar granules, separated from KLK5 and KLK7, and is secreted in the extracellular spaces of the superficial stratum granulosum

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P49862

IDA

extracellular space

1 reference

8 April 2019

Kallikrein-mediated proteolysis regulates the antimicrobial effects of cathelicidins in skin

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P49862

secretory granule

IBA

1 reference

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P49862

positive regulation of antibacterial peptide production

IBA

biological process

1 reference

27 March 2018

Kallikrein-mediated proteolysis regulates the antimicrobial effects of cathelicidins in skin

http://www.ebi.ac.uk/QuickGO/annotations?protein=P49862&geneProductId=UniProtKB:P49862

extracellular matrix disassembly

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P49862

1 reference

8 April 2019

epidermis development

1 reference

8 April 2019

Cloning, expression, and characterization of stratum corneum chymotryptic enzyme. A skin-specific human serine proteinase

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P49862

positive regulation of antibacterial peptide production

IBA

serine proteases, trypsin domain

has part(s)

1 reference

Serine proteases, trypsin family, serine active site

1 reference

serine proteases, trypsin family, histidine active site

1 reference

Identifiers

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

13 November 2019

1 reference

1 reference

1 reference

1 reference

1 reference

1 reference

9 August 2016

1 reference

9 August 2016

1 reference

9 August 2016

1 reference

9 August 2016

1 reference

9 August 2016