(Q21122021)

English

Plakophilin 3

mammalian protein found in Homo sapiens

plakophilin-3
PKP3
plakophilin 3b

In more languages

Statements

1 reference

13 November 2019

UniProt protein ID

1 reference

13 November 2019

UniProt protein ID

1 reference

13 November 2019

UniProt protein ID

molecular function

alpha-catenin binding

determination method

1 reference

8 April 2019

Mutations in the area composita protein αT-catenin are associated with arrhythmogenic right ventricular cardiomyopathy

British Heart Foundation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Y446

determination method

cell adhesion molecule binding

determination method

1 reference

8 April 2019

E-cadherin and plakoglobin recruit plakophilin3 to the cell border to initiate desmosome assembly

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Y446

determination method

cadherin binding involved in cell-cell adhesion

determination method

1 reference

31 October 2017

E-cadherin interactome complexity and robustness resolved by quantitative proteomics

British Heart Foundation

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9Y446&geneProductId=UniProtKB:Q9Y446

determination method

determination method

1 reference

8 April 2019

Plakophilins 1 and 3 bind to FXR1 and thereby influence the mRNA stability of desmosomal proteins

Critical Assessment of Protein Function Annotation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Y446

determination method

protein binding

determination method

1 reference

8 April 2019

Plakophilins 1 and 3 bind to FXR1 and thereby influence the mRNA stability of desmosomal proteins

Critical Assessment of Protein Function Annotation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Y446

determination method

determination method

1 reference

8 April 2019

Plakophilins 1 and 3 bind to FXR1 and thereby influence the mRNA stability of desmosomal proteins

Critical Assessment of Protein Function Annotation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Y446

determination method

translation regulator activity

determination method

1 reference

8 April 2019

Plakophilins 1 and 3 bind to FXR1 and thereby influence the mRNA stability of desmosomal proteins

Critical Assessment of Protein Function Annotation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Y446

determination method

cadherin binding

determination method

1 reference

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Y446

determination method

cadherin binding involved in cell-cell adhesion

determination method

1 reference

8 April 2019

E-cadherin interactome complexity and robustness resolved by quantitative proteomics

British Heart Foundation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Y446

determination method

cell-cell junction

determination method

1 reference

31 October 2017

Plakophilin 3--a novel cell-type-specific desmosomal plaque protein

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9Y446&geneProductId=UniProtKB:Q9Y446

determination method

cornified envelope

determination method

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Y446

determination method

determination method

1 reference

8 April 2019

Human Protein Atlas

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Y446

determination method

messenger ribonucleoprotein complex

determination method

1 reference

8 April 2019

Plakophilins 1 and 3 bind to FXR1 and thereby influence the mRNA stability of desmosomal proteins

Critical Assessment of Protein Function Annotation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Y446

determination method

determination method

determination method

1 reference

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Y446

determination method

plasma membrane

determination method

3 references

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Y446

determination method

8 April 2019

E-cadherin and plakoglobin recruit plakophilin3 to the cell border to initiate desmosome assembly

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Y446

determination method

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Y446

determination method

biological process

desmosome assembly

determination method

1 reference

8 April 2019

E-cadherin and plakoglobin recruit plakophilin3 to the cell border to initiate desmosome assembly

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Y446

determination method

determination method

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Y446

determination method

determination method

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Y446

determination method

regulation of translation

determination method

1 reference

31 October 2017

Plakophilins 1 and 3 bind to FXR1 and thereby influence the mRNA stability of desmosomal proteins

Critical Assessment of Protein Function Annotation

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9Y446&geneProductId=UniProtKB:Q9Y446

determination method

positive regulation of gene expression

determination method

1 reference

8 April 2019

Plakophilins 1 and 3 bind to FXR1 and thereby influence the mRNA stability of desmosomal proteins

Critical Assessment of Protein Function Annotation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Y446

determination method

negative regulation of mRNA catabolic process

determination method

1 reference

8 April 2019

Plakophilins 1 and 3 bind to FXR1 and thereby influence the mRNA stability of desmosomal proteins

Critical Assessment of Protein Function Annotation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Y446

determination method

protein localization to plasma membrane

determination method

1 reference

8 April 2019

E-cadherin and plakoglobin recruit plakophilin3 to the cell border to initiate desmosome assembly

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Y446

determination method

cell-cell adhesion

determination method

1 reference

31 October 2017

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9Y446&geneProductId=UniProtKB:Q9Y446

determination method

cell-cell junction assembly

determination method

1 reference

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Y446

determination method

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/Q9Y446

Identifiers

RefSeq protein ID

1 reference

30 May 2020

1 reference

30 May 2020

UniProt protein ID

1 reference

13 November 2019

UniProt protein ID

Ensembl protein ID

ENSP00000331678

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000331678

ENSP00000434110

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000434110

ENSP00000434517

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000434517

ENSP00000435383

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000435383

ENSP00000435478

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000435478

ENSP00000435522

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000435522

ENSP00000436847

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000436847

Sitelinks

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Multilingual sites(0 entries)

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