(Q21122198)

Cystine-knot cytokine

1 reference

Transforming growth factor-beta, C-terminal domain, protein family

1 reference

based on heuristic

inferred from protein domain or family

TGF-beta, propeptide family

1 reference

based on heuristic

inferred from protein domain or family

Transforming growth factor beta, conserved site, protein family

1 reference

based on heuristic

inferred from protein domain or family

1 reference

13 November 2019

1 reference

13 November 2019

type III transforming growth factor beta receptor binding

1 reference

8 April 2019

Cloning and developmental expression of the chick type II and type III TGF beta receptors

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P10600

1 reference

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P10600

type I transforming growth factor beta receptor binding

1 reference

8 April 2019

Cooperative assembly of TGF-beta superfamily signaling complexes is mediated by two disparate mechanisms and distinct modes of receptor binding

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P10600

9 references

8 April 2019

Mechanisms for asporin function and regulation in articular cartilage

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P10600

8 April 2019

Specific sequence motif of 8-Cys repeats of TGF-beta binding proteins, LTBPs, creates a hydrophobic interaction surface for binding of small latent TGF-beta

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P10600

8 April 2019

Crystal structure of the human TbetaR2 ectodomain--TGF-beta3 complex

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P10600

8 April 2019

TGF-β signalling is mediated by two autonomously functioning TβRI:TβRII pairs

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P10600

8 April 2019

The soluble exoplasmic domain of the type II transforming growth factor (TGF)-beta receptor. A heterogeneously glycosylated protein with high affinity and selectivity for TGF-beta ligands

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P10600

8 April 2019

Cooperative assembly of TGF-beta superfamily signaling complexes is mediated by two disparate mechanisms and distinct modes of receptor binding

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P10600

8 April 2019

Endoglin is a component of the transforming growth factor-beta receptor system in human endothelial cells

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P10600

8 April 2019

Endoglin is an accessory protein that interacts with the signaling receptor complex of multiple members of the transforming growth factor-beta superfamily

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P10600

8 April 2019

Type III TGF-beta receptor-independent signalling of TGF-beta2 via TbetaRII-B, an alternatively spliced TGF-beta type II receptor

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P10600

protein heterodimerization activity

IPI

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P10600

transforming growth factor beta receptor binding

1 reference

5 June 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=P10600&geneProductId=UniProtKB:P10600

transforming growth factor beta binding

1 reference

8 April 2019

Cooperative assembly of TGF-beta superfamily signaling complexes is mediated by two disparate mechanisms and distinct modes of receptor binding

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P10600

type II transforming growth factor beta receptor binding

4 references

5 June 2018

TGF beta signals through a heteromeric protein kinase receptor complex

http://www.ebi.ac.uk/QuickGO/annotations?protein=P10600&geneProductId=UniProtKB:P10600

5 June 2018

Cloning and developmental expression of the chick type II and type III TGF beta receptors

http://www.ebi.ac.uk/QuickGO/annotations?protein=P10600&geneProductId=UniProtKB:P10600

5 June 2018

Type III TGF-beta receptor-independent signalling of TGF-beta2 via TbetaRII-B, an alternatively spliced TGF-beta type II receptor

http://www.ebi.ac.uk/QuickGO/annotations?protein=P10600&geneProductId=UniProtKB:P10600

5 June 2018

Cooperative assembly of TGF-beta superfamily signaling complexes is mediated by two disparate mechanisms and distinct modes of receptor binding

http://www.ebi.ac.uk/QuickGO/annotations?protein=P10600&geneProductId=UniProtKB:P10600

identical protein binding

3 references

8 April 2019

A cytokine-neutralizing antibody as a structural mimetic of 2 receptor interactions

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P10600

8 April 2019

TGF-β signalling is mediated by two autonomously functioning TβRI:TβRII pairs

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P10600

8 April 2019

Cooperative assembly of TGF-beta superfamily signaling complexes is mediated by two disparate mechanisms and distinct modes of receptor binding

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P10600

type II transforming growth factor beta receptor binding

5 references

8 April 2019

TGF beta signals through a heteromeric protein kinase receptor complex

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P10600

8 April 2019

Cloning and developmental expression of the chick type II and type III TGF beta receptors

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P10600

8 April 2019

Cooperative assembly of TGF-beta superfamily signaling complexes is mediated by two disparate mechanisms and distinct modes of receptor binding

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P10600

8 April 2019

Type III TGF-beta receptor-independent signalling of TGF-beta2 via TbetaRII-B, an alternatively spliced TGF-beta type II receptor

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P10600

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P10600

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P10600

1 reference

24 April 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=P10600&geneProductId=UniProtKB:P10600

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P10600

1 reference

8 April 2019

Type III TGF-beta receptor-independent signalling of TGF-beta2 via TbetaRII-B, an alternatively spliced TGF-beta type II receptor

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P10600

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P10600

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P10600

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P10600

platelet alpha granule lumen

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P10600

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P10600

intracellular membrane-bounded organelle

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P10600

collagen-containing extracellular matrix

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P10600

regulation of apoptotic process

biological process

1 reference

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P10600

negative regulation of neuron apoptotic process

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P10600

positive regulation of collagen biosynthetic process

1 reference

8 April 2019

Human leiomyoma smooth muscle cells show increased expression of transforming growth factor-beta 3 (TGF beta 3) and altered responses to the antiproliferative effects of TGF beta

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P10600

cell-cell junction organization

IMP

1 reference

8 April 2019

Transforming growth factor-beta1, transforming growth factor-beta2, and transforming growth factor-beta3 enhance ovarian cancer metastatic potential by inducing a Smad3-dependent epithelial-to-mesenchymal transition

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P10600

regulation of MAPK cascade

1 reference

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P10600

SMAD protein signal transduction

1 reference

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P10600

positive regulation of bone mineralization

1 reference

8 April 2019

Bone formation zones in heterotopic ossifications: histologic findings and increased expression of bone morphogenetic protein 2 and transforming growth factors beta2 and beta3

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P10600

embryonic neurocranium morphogenesis

IEP

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P10600

Opposite regulation of transforming growth factors-beta2 and -beta3 expression in the human endometrium

response to progesterone

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P10600

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P10600

response to laminar fluid shear stress

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P10600

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P10600

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P10600

platelet degranulation

1 reference

8 April 2019

in utero embryonic development

TAS

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P10600

negative regulation of transforming growth factor beta receptor signaling pathway

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P10600

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P10600

salivary gland morphogenesis

1 reference

8 April 2019

Developing human minor salivary glands: morphological parallel relation between the expression of TGF-beta isoforms and cytoskeletal markers of glandular maturation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P10600

mammary gland development

IEP

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P10600

1 reference

8 April 2019

Expression of transforming growth factor-beta 1, -beta 2, and -beta 3 in human developing teeth: immunolocalization according to the odontogenesis phases

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P10600

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P10600

positive regulation of protein secretion

1 reference

8 April 2019

Transforming growth factor-beta1, transforming growth factor-beta2, and transforming growth factor-beta3 enhance ovarian cancer metastatic potential by inducing a Smad3-dependent epithelial-to-mesenchymal transition

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P10600

ossification involved in bone remodeling

1 reference

8 April 2019

Bone formation zones in heterotopic ossifications: histologic findings and increased expression of bone morphogenetic protein 2 and transforming growth factors beta2 and beta3

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P10600

Opposite regulation of transforming growth factors-beta2 and -beta3 expression in the human endometrium

IEP

uterine wall breakdown

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P10600

frontal suture morphogenesis

TAS

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P10600

inner ear development

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P10600

negative regulation of macrophage cytokine production

1 reference

8 April 2019

TGF-β2 suppresses macrophage cytokine production and mucosal inflammatory responses in the developing intestine

Developmental FunctionaL Annotation at Tufts

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P10600

lung alveolus development

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P10600

digestive tract development

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P10600

transforming growth factor beta receptor signaling pathway

positive regulation of filopodium assembly

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P10600

positive regulation of cell division

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P10600

1 reference

8 April 2019

MSX1 and TGFB3 contribute to clefting in South America

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P10600

1 reference

8 April 2019

Severe intrauterine growth restriction pregnancies have increased placental endoglin levels: hypoxic regulation via transforming growth factor-beta 3

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P10600

positive regulation of transcription by RNA polymerase II

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P10600

positive regulation of SMAD protein signal transduction

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P10600

positive regulation of tight junction disassembly

1 reference

8 April 2019

Signaling via the Tgf-beta type I receptor Alk5 in heart development

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P10600

positive regulation of epithelial to mesenchymal transition

3 references

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P10600

8 April 2019

Transforming growth factor-beta1, transforming growth factor-beta2, and transforming growth factor-beta3 enhance ovarian cancer metastatic potential by inducing a Smad3-dependent epithelial-to-mesenchymal transition

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P10600

8 April 2019

Signaling via the Tgf-beta type I receptor Alk5 in heart development

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P10600

positive regulation of stress fiber assembly

1 reference

8 April 2019

Signaling via the Tgf-beta type I receptor Alk5 in heart development

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P10600

regulation of epithelial to mesenchymal transition involved in endocardial cushion formation

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P10600

negative regulation of vascular associated smooth muscle cell proliferation

1 reference

8 April 2019

XBP 1-Deficiency Abrogates Neointimal Lesion of Injured Vessels Via Cross Talk With the PDGF Signaling

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P10600

http://www.ebi.ac.uk/QuickGO/annotations?protein=P10600&geneProductId=UniProtKB:P10600

BMP signaling pathway

1 reference

5 June 2018

1 reference

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P10600

regulation of signaling receptor activity

1 reference

8 April 2019

Gene Ontology Consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P10600

positive regulation of cell population proliferation

1 reference

8 April 2019

Human leiomyoma smooth muscle cells show increased expression of transforming growth factor-beta 3 (TGF beta 3) and altered responses to the antiproliferative effects of TGF beta

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P10600

negative regulation of cell population proliferation

IMP

3 references

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P10600

8 April 2019

Human leiomyoma smooth muscle cells show increased expression of transforming growth factor-beta 3 (TGF beta 3) and altered responses to the antiproliferative effects of TGF beta

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P10600

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P10600

secondary palate development

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P10600

transforming growth factor beta receptor signaling pathway

3 references

8 April 2019

Type III TGF-beta receptor-independent signalling of TGF-beta2 via TbetaRII-B, an alternatively spliced TGF-beta type II receptor

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P10600

8 April 2019

Signaling via the Tgf-beta type I receptor Alk5 in heart development

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P10600

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P10600

regulation of cell population proliferation

1 reference

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P10600

Transforming growth factor beta, conserved site

has part(s)

1 reference

Transforming growth factor-beta, C-terminal

1 reference

TGF-beta, propeptide

1 reference

Identifiers

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

13 November 2019

1 reference

1 reference

1 reference

9 August 2016

1 reference

9 August 2016

1 reference

9 August 2016

1 reference

9 August 2016

1 reference

9 August 2016

1 reference

9 August 2016