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MIS12 kinetochore complex component
mammalian protein found in Homo sapiens
MIS12
homolog of yeast Mis12
MIS12, MIND kinetochore complex component, homolog
MIS12 homolog
protein MIS12 homolog
In more languages
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Statements
instance of
protein
1 reference
stated in
UniProt
retrieved
13 November 2019
UniProt protein ID
Q9H081
part of
Centromere protein Mis12
1 reference
stated in
InterPro Release 71.0
reference URL
http://www.ebi.ac.uk/interpro/protein/Q9H081
found in taxon
Homo sapiens
1 reference
stated in
UniProt
retrieved
13 November 2019
UniProt protein ID
Q9H081
encoded by
MIS12
1 reference
stated in
UniProt
retrieved
13 November 2019
UniProt protein ID
Q9H081
molecular function
protein binding
determination method
IPI
5 references
retrieved
1 January 2018
stated in
A conserved Mis12 centromere complex is linked to heterochromatic HP1 and outer kinetochore protein Zwint-1
GOA
curator
UniProt
UniProt protein ID
Q9H081
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9H081
determination method
IPI
retrieved
1 January 2018
stated in
A conserved protein network controls assembly of the outer kinetochore and its ability to sustain tension
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9H081
determination method
IPI
retrieved
1 January 2018
stated in
Systematic analysis of human protein complexes identifies chromosome segregation proteins
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9H081
determination method
IPI
retrieved
1 January 2018
stated in
A proteome-scale map of the human interactome network
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9H081
determination method
IPI
retrieved
1 January 2018
stated in
A human interactome in three quantitative dimensions organized by stoichiometries and abundances
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9H081
determination method
IPI
cell component
chromosome
determination method
IEA
1 reference
retrieved
1 January 2018
stated in
GOA
curator
UniProt
UniProt protein ID
Q9H081
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9H081
determination method
IEA
cytosol
determination method
TAS
1 reference
retrieved
1 January 2018
stated in
GOA
curator
Reactome
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9H081
determination method
TAS
MIS12/MIND type complex
determination method
IDA
1 reference
retrieved
1 January 2018
stated in
The human Mis12 complex is required for kinetochore assembly and proper chromosome segregation.
GOA
curator
UniProt
UniProt protein ID
Q9H081
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9H081
determination method
IDA
chromosome, centromeric region
determination method
IEA
2 references
retrieved
1 January 2018
stated in
GOA
curator
UniProt
UniProt protein ID
Q9H081
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9H081
determination method
IEA
retrieved
1 January 2018
stated in
GOA
curator
InterPro
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9H081
determination method
IEA
nucleus
determination method
IDA
IEA
2 references
retrieved
1 January 2018
stated in
GOA
curator
InterPro
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9H081
determination method
IEA
retrieved
1 January 2018
stated in
GOA
curator
LifeDB
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9H081
determination method
IDA
kinetochore
determination method
IEA
1 reference
retrieved
1 January 2018
stated in
GOA
curator
UniProt
UniProt protein ID
Q9H081
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9H081
determination method
IEA
nuclear MIS12/MIND complex
determination method
IBA
1 reference
retrieved
1 January 2018
stated in
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
GOA
curator
GO Central
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9H081
determination method
IBA
biological process
chromosome segregation
determination method
IEA
IMP
3 references
retrieved
1 January 2018
stated in
The human Mis12 complex is required for kinetochore assembly and proper chromosome segregation.
GOA
curator
UniProt
UniProt protein ID
Q9H081
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9H081
determination method
IMP
retrieved
1 January 2018
stated in
Human centromere chromatin protein hMis12, essential for equal segregation, is independent of CENP-A loading pathway
GOA
curator
UniProt
UniProt protein ID
Q9H081
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9H081
determination method
IMP
retrieved
1 January 2018
stated in
GOA
curator
UniProt
UniProt protein ID
Q9H081
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9H081
determination method
IEA
cell division
determination method
IEA
1 reference
retrieved
1 January 2018
stated in
GOA
curator
UniProt
UniProt protein ID
Q9H081
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9H081
determination method
IEA
cell cycle
determination method
IEA
1 reference
retrieved
1 January 2018
stated in
GOA
curator
UniProt
UniProt protein ID
Q9H081
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9H081
determination method
IEA
kinetochore assembly
determination method
IDA
1 reference
retrieved
24 April 2018
stated in
The human Mis12 complex is required for kinetochore assembly and proper chromosome segregation.
GOA
curator
UniProt
UniProt protein ID
Q9H081
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9H081&geneProductId=UniProtKB:Q9H081
determination method
IDA
attachment of mitotic spindle microtubules to kinetochore
determination method
IMP
1 reference
retrieved
1 January 2018
stated in
Lateral to end-on conversion of chromosome-microtubule attachment requires kinesins CENP-E and MCAK
GOA
curator
UniProt
UniProt protein ID
Q9H081
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9H081
determination method
IMP
mitotic cell cycle
determination method
IEA
1 reference
retrieved
1 January 2018
stated in
GOA
curator
InterPro
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9H081
determination method
IEA
protein localization to kinetochore
determination method
IBA
1 reference
retrieved
1 January 2018
stated in
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
GOA
curator
GO Central
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9H081
determination method
IBA
mitotic sister chromatid segregation
determination method
IBA
1 reference
retrieved
1 January 2018
stated in
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
GOA
curator
GO Central
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9H081
determination method
IBA
kinetochore assembly
determination method
IBA
IDA
2 references
retrieved
1 January 2018
stated in
The human Mis12 complex is required for kinetochore assembly and proper chromosome segregation.
GOA
curator
UniProt
UniProt protein ID
Q9H081
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9H081
determination method
IDA
retrieved
1 January 2018
stated in
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
GOA
curator
GO Central
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9H081
determination method
IBA
Identifiers
RefSeq protein ID
NP_001245146
1 reference
stated in
NCBI Gene
retrieved
30 May 2020
Entrez Gene ID
79003
NP_001245147
1 reference
stated in
NCBI Gene
retrieved
30 May 2020
Entrez Gene ID
79003
NP_001245148
1 reference
stated in
NCBI Gene
retrieved
30 May 2020
Entrez Gene ID
79003
NP_001245149
1 reference
stated in
NCBI Gene
retrieved
30 May 2020
Entrez Gene ID
79003
NP_076944
1 reference
stated in
NCBI Gene
retrieved
30 May 2020
Entrez Gene ID
79003
XP_005256854
1 reference
stated in
NCBI Gene
retrieved
30 May 2020
Entrez Gene ID
79003
XP_016880522
1 reference
stated in
NCBI Gene
retrieved
30 May 2020
Entrez Gene ID
79003
XP_016880523
1 reference
stated in
NCBI Gene
retrieved
30 May 2020
Entrez Gene ID
79003
XP_024306692
1 reference
stated in
NCBI Gene
retrieved
30 May 2020
Entrez Gene ID
79003
UniProt protein ID
Q9H081
1 reference
stated in
UniProt
retrieved
13 November 2019
UniProt protein ID
Q9H081
Ensembl protein ID
ENSP00000370557
1 reference
stated in
Ensembl Release 99
Ensembl protein ID
ENSP00000370557
ENSP00000461252
1 reference
stated in
Ensembl Release 99
Ensembl protein ID
ENSP00000461252
ENSP00000484532
1 reference
stated in
Ensembl Release 99
Ensembl protein ID
ENSP00000484532
ENSP00000459366
1 reference
stated in
Ensembl Release 99
Ensembl protein ID
ENSP00000459366
ENSP00000461333
1 reference
stated in
Ensembl Release 99
Ensembl protein ID
ENSP00000461333
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