(Q21123028)

English

N-alpha-acetyltransferase 60, NatF catalytic subunit

mammalian protein found in Homo sapiens

epididymis secretory sperm binding protein
HAT4
N-acetyltransferase 15 (GCN5-related, putative)
N-alpha-acetyltransferase 60
NatF catalytic subunit
histone acetyltransferase type B protein 4
NAA60
N-acetyltransferase 15
N-alpha-acetyltransferase F

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Statements

1 reference

13 November 2019

Acyl-CoA N-acyltransferase

1 reference

stated in

InterPro Release 71.0

reference URL

http://www.ebi.ac.uk/interpro/protein/Q9H7X0

GNAT domain, protein family

1 reference

based on heuristic

inferred from protein domain or family

1 reference

13 November 2019

1 reference

13 November 2019

histone acetyltransferase activity

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9H7X0

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9H7X0

determination method

IEA

H4 histone acetyltransferase activity

1 reference

8 April 2019

HAT4, a Golgi apparatus-anchored B-type histone acetyltransferase, acetylates free histone H4 and facilitates chromatin assembly

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9H7X0

determination method

IDA

acyltransferase activity

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9H7X0

determination method

IEA

peptide alpha-N-acetyltransferase activity

5 references

27 March 2018

Crystal Structure of the Golgi-Associated Human Nα-Acetyltransferase 60 Reveals the Molecular Determinants for Substrate-Specific Acetylation

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9H7X0&geneProductId=UniProtKB:Q9H7X0

27 March 2018

HAT4, a Golgi apparatus-anchored B-type histone acetyltransferase, acetylates free histone H4 and facilitates chromatin assembly

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9H7X0&geneProductId=UniProtKB:Q9H7X0

27 March 2018

NatF contributes to an evolutionary shift in protein N-terminal acetylation and is important for normal chromosome segregation

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9H7X0&geneProductId=UniProtKB:Q9H7X0

27 March 2018

Structure and function of human Naa60 (NatF), a Golgi-localized bi-functional acetyltransferase

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9H7X0&geneProductId=UniProtKB:Q9H7X0

27 March 2018

An organellar nα-acetyltransferase, naa60, acetylates cytosolic N termini of transmembrane proteins and maintains Golgi integrity

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9H7X0&geneProductId=UniProtKB:Q9H7X0

determination method

IDA

protein homodimerization activity

1 reference

8 April 2019

Crystal Structure of the Golgi-Associated Human Nα-Acetyltransferase 60 Reveals the Molecular Determinants for Substrate-Specific Acetylation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9H7X0

determination method

IDA

peptide alpha-N-acetyltransferase activity

6 references

8 April 2019

HAT4, a Golgi apparatus-anchored B-type histone acetyltransferase, acetylates free histone H4 and facilitates chromatin assembly

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9H7X0

8 April 2019

NatF contributes to an evolutionary shift in protein N-terminal acetylation and is important for normal chromosome segregation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9H7X0

8 April 2019

An organellar nα-acetyltransferase, naa60, acetylates cytosolic N termini of transmembrane proteins and maintains Golgi integrity

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9H7X0

8 April 2019

Crystal Structure of the Golgi-Associated Human Nα-Acetyltransferase 60 Reveals the Molecular Determinants for Substrate-Specific Acetylation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9H7X0

8 April 2019

Structure and function of human Naa60 (NatF), a Golgi-localized bi-functional acetyltransferase

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9H7X0

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9H7X0

3 references

27 March 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9H7X0&geneProductId=UniProtKB:Q9H7X0

27 March 2018

HAT4, a Golgi apparatus-anchored B-type histone acetyltransferase, acetylates free histone H4 and facilitates chromatin assembly

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9H7X0&geneProductId=UniProtKB:Q9H7X0

27 March 2018

An organellar nα-acetyltransferase, naa60, acetylates cytosolic N termini of transmembrane proteins and maintains Golgi integrity

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9H7X0&geneProductId=UniProtKB:Q9H7X0

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9H7X0

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9H7X0

4 references

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9H7X0

8 April 2019

HAT4, a Golgi apparatus-anchored B-type histone acetyltransferase, acetylates free histone H4 and facilitates chromatin assembly

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9H7X0

8 April 2019

An organellar nα-acetyltransferase, naa60, acetylates cytosolic N termini of transmembrane proteins and maintains Golgi integrity

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9H7X0

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9H7X0

determination method

IBA

biological process

histone H4 acetylation

1 reference

27 March 2018

HAT4, a Golgi apparatus-anchored B-type histone acetyltransferase, acetylates free histone H4 and facilitates chromatin assembly

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9H7X0&geneProductId=UniProtKB:Q9H7X0

1 reference

8 April 2019

HAT4, a Golgi apparatus-anchored B-type histone acetyltransferase, acetylates free histone H4 and facilitates chromatin assembly

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9H7X0

determination method

IDA

cell population proliferation

1 reference

8 April 2019

HAT4, a Golgi apparatus-anchored B-type histone acetyltransferase, acetylates free histone H4 and facilitates chromatin assembly

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9H7X0

determination method

IMP

N-terminal peptidyl-methionine acetylation

1 reference

27 March 2018

NatF contributes to an evolutionary shift in protein N-terminal acetylation and is important for normal chromosome segregation

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9H7X0&geneProductId=UniProtKB:Q9H7X0

determination method

IDA

N-terminal protein amino acid acetylation

3 references

8 April 2019

Crystal Structure of the Golgi-Associated Human Nα-Acetyltransferase 60 Reveals the Molecular Determinants for Substrate-Specific Acetylation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9H7X0

8 April 2019

An organellar nα-acetyltransferase, naa60, acetylates cytosolic N termini of transmembrane proteins and maintains Golgi integrity

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9H7X0

8 April 2019

Structure and function of human Naa60 (NatF), a Golgi-localized bi-functional acetyltransferase

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9H7X0

determination method

IDA

chromosome segregation

chromatin organization

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9H7X0

determination method

IEA

N-terminal peptidyl-methionine acetylation

determination method

IBA

IDA

histone H3 acetylation

1 reference

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9H7X0

1 reference

InterPro Release 71.0

reference URL

http://www.ebi.ac.uk/interpro/protein/Q9H7X0

Identifiers

1 reference

30 May 2020

1 reference

30 May 2020

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30 May 2020

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30 May 2020

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30 May 2020

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30 May 2020

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30 May 2020

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

13 November 2019

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1 reference

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1 reference

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1 reference

1 reference

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1 reference

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1 reference

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1 reference

1 reference

1 reference

5 August 2016

language of work or name

1 reference

5 August 2016

language of work or name

English

(Q21123028)

N-alpha-acetyltransferase 60, NatF catalytic subunit

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