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Prune exopolyphosphatase 1
mammalian protein found in Homo sapiens
HTcD37
PRUNE1
DRES-17
exopolyphosphatase PRUNE1
protein prune homolog
DRES17
protein prune homolog 1
Drosophila-related expressed sequence 17
In more languages
edit
Statements
instance of
protein
1 reference
stated in
UniProt
retrieved
13 November 2019
UniProt protein ID
Q86TP1
part of
DHHA2 domain superfamily
1 reference
stated in
InterPro Release 71.0
reference URL
http://www.ebi.ac.uk/interpro/protein/Q86TP1
DHH phosphoesterase superfamily
1 reference
stated in
InterPro Release 71.0
reference URL
http://www.ebi.ac.uk/interpro/protein/Q86TP1
DHHA2 domain, protein family
1 reference
based on heuristic
inferred from protein domain or family
DHH domain, protein family
1 reference
based on heuristic
inferred from protein domain or family
found in taxon
Homo sapiens
1 reference
stated in
UniProt
retrieved
13 November 2019
UniProt protein ID
Q86TP1
encoded by
PRUNE1
1 reference
stated in
UniProt
retrieved
13 November 2019
UniProt protein ID
Q86TP1
molecular function
pyrophosphatase activity
determination method
IEA
1 reference
retrieved
8 April 2019
stated in
GOA
curator
InterPro
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q86TP1
determination method
IEA
protein binding
determination method
IPI
1 reference
retrieved
8 April 2019
stated in
Evidence for interaction between human PRUNE and nm23-H1 NDPKinase
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q86TP1
determination method
IPI
hydrolase activity
determination method
IEA
1 reference
retrieved
8 April 2019
stated in
GOA
curator
UniProt
UniProt protein ID
Q86TP1
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q86TP1
determination method
IEA
Inorganic pyrophosphatase
determination method
IEA
1 reference
retrieved
8 April 2019
stated in
GOA
curator
UniProt
UniProt protein ID
Q86TP1
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q86TP1
determination method
IEA
metal ion binding
determination method
IEA
1 reference
retrieved
8 April 2019
stated in
GOA
curator
UniProt
UniProt protein ID
Q86TP1
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q86TP1
determination method
IEA
tubulin binding
determination method
IDA
1 reference
retrieved
8 April 2019
stated in
PRUNE is crucial for normal brain development and mutated in microcephaly with neurodevelopmental impairment
GOA
curator
UniProt
UniProt protein ID
Q86TP1
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q86TP1
determination method
IDA
phosphatase activity
determination method
IDA
1 reference
retrieved
8 April 2019
stated in
PRUNE is crucial for normal brain development and mutated in microcephaly with neurodevelopmental impairment
GOA
curator
UniProt
UniProt protein ID
Q86TP1
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q86TP1
determination method
IDA
exopolyphosphatase activity
determination method
IBA
1 reference
retrieved
8 April 2019
stated in
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
GOA
curator
GO Central
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q86TP1
determination method
IBA
cell component
cell junction
determination method
IEA
1 reference
retrieved
8 April 2019
stated in
GOA
curator
UniProt
UniProt protein ID
Q86TP1
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q86TP1
determination method
IEA
nucleus
determination method
IEA
1 reference
retrieved
8 April 2019
stated in
GOA
curator
UniProt
UniProt protein ID
Q86TP1
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q86TP1
determination method
IEA
focal adhesion
determination method
IEA
1 reference
retrieved
8 April 2019
stated in
GOA
curator
UniProt
UniProt protein ID
Q86TP1
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q86TP1
determination method
IEA
cytoplasm
determination method
IEA
2 references
retrieved
27 March 2018
stated in
GOA
curator
UniProt
UniProt protein ID
Q86TP1
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=Q86TP1&geneProductId=UniProtKB:Q86TP1
determination method
IEA
retrieved
27 March 2018
stated in
GOA
curator
InterPro
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=Q86TP1&geneProductId=UniProtKB:Q86TP1
determination method
IEA
cytosol
determination method
IDA
1 reference
retrieved
8 April 2019
stated in
GOA
curator
Human Protein Atlas
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q86TP1
determination method
IDA
cytoplasm
determination method
IBA
IEA
3 references
retrieved
8 April 2019
stated in
GOA
curator
UniProt
UniProt protein ID
Q86TP1
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q86TP1
determination method
IEA
retrieved
8 April 2019
stated in
GOA
curator
InterPro
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q86TP1
determination method
IEA
retrieved
8 April 2019
stated in
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
GOA
curator
GO Central
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q86TP1
determination method
IBA
biological process
dephosphorylation
determination method
IEA
1 reference
retrieved
8 April 2019
stated in
GOA
curator
Gene Ontology Consortium
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q86TP1
determination method
IEA
regulation of microtubule polymerization
determination method
IMP
1 reference
retrieved
8 April 2019
stated in
PRUNE is crucial for normal brain development and mutated in microcephaly with neurodevelopmental impairment
GOA
curator
UniProt
UniProt protein ID
Q86TP1
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q86TP1
determination method
IMP
regulation of neurogenesis
determination method
IMP
1 reference
retrieved
8 April 2019
stated in
PRUNE is crucial for normal brain development and mutated in microcephaly with neurodevelopmental impairment
GOA
curator
UniProt
UniProt protein ID
Q86TP1
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q86TP1
determination method
IMP
polyphosphate catabolic process
determination method
IBA
1 reference
retrieved
8 April 2019
stated in
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
GOA
curator
GO Central
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q86TP1
determination method
IBA
has part(s)
DDH domain
1 reference
stated in
InterPro Release 71.0
reference URL
http://www.ebi.ac.uk/interpro/protein/Q86TP1
DHHA2 domain
1 reference
stated in
InterPro Release 71.0
reference URL
http://www.ebi.ac.uk/interpro/protein/Q86TP1
Identifiers
RefSeq protein ID
NP_001290158
1 reference
stated in
NCBI Gene
retrieved
30 May 2020
Entrez Gene ID
58497
NP_001290171
1 reference
stated in
NCBI Gene
retrieved
30 May 2020
Entrez Gene ID
58497
NP_001290172
1 reference
stated in
NCBI Gene
retrieved
30 May 2020
Entrez Gene ID
58497
NP_067045
1 reference
stated in
NCBI Gene
retrieved
30 May 2020
Entrez Gene ID
58497
XP_005245450
1 reference
stated in
NCBI Gene
retrieved
30 May 2020
Entrez Gene ID
58497
XP_011508134
1 reference
stated in
NCBI Gene
retrieved
30 May 2020
Entrez Gene ID
58497
XP_016857444
1 reference
stated in
NCBI Gene
retrieved
30 May 2020
Entrez Gene ID
58497
XP_016857445
1 reference
stated in
NCBI Gene
retrieved
30 May 2020
Entrez Gene ID
58497
XP_016857446
1 reference
stated in
NCBI Gene
retrieved
30 May 2020
Entrez Gene ID
58497
UniProt protein ID
Q86TP1
1 reference
stated in
UniProt
retrieved
13 November 2019
UniProt protein ID
Q86TP1
Ensembl protein ID
ENSP00000271620
1 reference
stated in
Ensembl Release 99
Ensembl protein ID
ENSP00000271620
ENSP00000357930
1 reference
stated in
Ensembl Release 99
Ensembl protein ID
ENSP00000357930
ENSP00000357931
1 reference
stated in
Ensembl Release 99
Ensembl protein ID
ENSP00000357931
ENSP00000357932
1 reference
stated in
Ensembl Release 99
Ensembl protein ID
ENSP00000357932
ENSP00000357933
1 reference
stated in
Ensembl Release 99
Ensembl protein ID
ENSP00000357933
ENSP00000387696
1 reference
stated in
Ensembl Release 99
Ensembl protein ID
ENSP00000387696
ENSP00000392632
1 reference
stated in
Ensembl Release 99
Ensembl protein ID
ENSP00000392632
ENSP00000497847
1 reference
stated in
Ensembl Release 99
Ensembl protein ID
ENSP00000497847
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