(Q21123054)

English

NADH:ubiquinone oxidoreductase subunit A8

mammalian protein found in Homo sapiens

complex I-PGIV
complex I-19kD
NADH:ubiquinone oxidoreductase PGIV subunit
NADH-ubiquinone oxidoreductase 19 kDa subunit
CI-PGIV
NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 8
NDUFA8
CI-19kD
NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 8, 19kDa

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Statements

1 reference

13 November 2019

NADH dehydrogenase [ubiquinone] (complex I), alpha subcomplex, subunit 8

1 reference

stated in

InterPro Release 71.0

reference URL

http://www.ebi.ac.uk/interpro/protein/P51970

CHCH, protein family

1 reference

based on heuristic

inferred from protein domain or family

1 reference

13 November 2019

1 reference

13 November 2019

NADH dehydrogenase (ubiquinone) activity

determination method

NAS

TAS

protein-containing complex binding

1 reference

8 April 2019

KIF14 negatively regulates Rap1a-Radil signaling during breast cancer progression

GOA

curator

Mouse Genome Informatics

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P51970

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P51970

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P51970

3 references

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P51970

8 April 2019

Protein import and oxidative folding in the mitochondrial intermembrane space of intact mammalian cells.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P51970

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P51970

determination method

IDA

mitochondrial respiratory chain complex I

4 references

27 March 2018

cDNA of eight nuclear encoded subunits of NADH:ubiquinone oxidoreductase: human complex I cDNA characterization completed

http://www.ebi.ac.uk/QuickGO/annotations?protein=P51970&geneProductId=UniProtKB:P51970

27 March 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=P51970&geneProductId=UniProtKB:P51970

27 March 2018

The subunit composition of the human NADH dehydrogenase obtained by rapid one-step immunopurification

http://www.ebi.ac.uk/QuickGO/annotations?protein=P51970&geneProductId=UniProtKB:P51970

27 March 2018

Accessory subunits are integral for assembly and function of human mitochondrial complex I.

http://www.ebi.ac.uk/QuickGO/annotations?protein=P51970&geneProductId=UniProtKB:P51970

determination method

IDA

mitochondrial respiratory chain complex I

5 references

8 April 2019

cDNA of eight nuclear encoded subunits of NADH:ubiquinone oxidoreductase: human complex I cDNA characterization completed

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P51970

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P51970

8 April 2019

Accessory subunits are integral for assembly and function of human mitochondrial complex I.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P51970

8 April 2019

The subunit composition of the human NADH dehydrogenase obtained by rapid one-step immunopurification

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P51970

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P51970

determination method

IBA

biological process

mitochondrial electron transport, NADH to ubiquinone

3 references

physically interacts with

1 reference

Open Targets Platform

retrieved

14 August 2023

reference URL

https://platform.opentargets.org/drug/CHEMBL1431

metformin hydrochloride

object has role

reaction inhibitor

1 reference

stated in

Open Targets Platform

retrieved

14 August 2023

reference URL

https://platform.opentargets.org/drug/CHEMBL1703

has part(s)

CHCH

1 reference

stated in

InterPro Release 71.0

reference URL

http://www.ebi.ac.uk/interpro/protein/P51970

Identifiers

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

13 November 2019

1 reference

(Q21123054)

NADH:ubiquinone oxidoreductase subunit A8

Statements

Identifiers

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