(Q21123065)

English

NADH:ubiquinone oxidoreductase complex assembly factor 4

mammalian protein found in Homo sapiens

NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, assembly factor 4
hormone-regulated proliferation-associated protein, 20 kDa
NADH dehydrogenase (ubiquinone) complex I, assembly factor 4
hormone-regulated proliferation-associated protein of 20 kDa
NDUFAF4
NADH dehydrogenase [ubiquinone] 1 alpha subcomplex assembly factor 4

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Statements

1 reference

13 November 2019

NADH dehydrogenase [ubiquinone] 1 alpha subcomplex assembly factor 4

1 reference

stated in

InterPro Release 71.0

reference URL

http://www.ebi.ac.uk/interpro/protein/Q9P032

1 reference

13 November 2019

1 reference

13 November 2019

6 references

8 April 2019

Mutations in NDUFAF3 (C3ORF60), encoding an NDUFAF4 (C6ORF66)-interacting complex I assembly protein, cause fatal neonatal mitochondrial disease

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9P032

8 April 2019

Mitochondrial Protein Interaction Mapping Identifies Regulators of Respiratory Chain Function

GOA

curator

IntAct protein interaction database

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9P032

8 April 2019

A proteome-scale map of the human interactome network

GOA

curator

IntAct protein interaction database

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9P032

8 April 2019

TIMMDC1/C3orf1 functions as a membrane-embedded mitochondrial complex I assembly factor through association with the MCIA complex

GOA

curator

IntAct protein interaction database

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9P032

8 April 2019

Widespread macromolecular interaction perturbations in human genetic disorders

GOA

curator

IntAct protein interaction database

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9P032

8 April 2019

LC-MS/MS as an alternative for SDS-PAGE in blue native analysis of protein complexes

GOA

curator

IntAct protein interaction database

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9P032

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9P032

determination method

IEA

cell component

mitochondrial inner membrane

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9P032

determination method

TAS

mitochondrial membranes

1 reference

8 April 2019

Mutations in NDUFAF3 (C3ORF60), encoding an NDUFAF4 (C6ORF66)-interacting complex I assembly protein, cause fatal neonatal mitochondrial disease

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9P032

3 references

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9P032

4 references

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9P032

8 April 2019

C6ORF66 is an assembly factor of mitochondrial complex I

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9P032

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9P032

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9P032

determination method

IBA

biological process

NADH dehydrogenase complex assembly

1 reference

8 April 2019

Ensembl genome database project

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9P032

determination method

IEA

mitochondrial respiratory chain complex I assembly

mitochondrial respiratory chain complex I assembly

4 references

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9P032

8 April 2019

C6ORF66 is an assembly factor of mitochondrial complex I

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9P032

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9P032

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9P032

determination method

IBA

physically interacts with

1 reference

Open Targets Platform

retrieved

14 August 2023

reference URL

https://platform.opentargets.org/drug/CHEMBL1431

metformin hydrochloride

object has role

reaction inhibitor

1 reference

stated in

Open Targets Platform

retrieved

14 August 2023

reference URL

https://platform.opentargets.org/drug/CHEMBL1703

Identifiers

1 reference

30 May 2020

1 reference

13 November 2019

1 reference

(Q21123065)

NADH:ubiquinone oxidoreductase complex assembly factor 4

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