(Q21123068)

English

NADH:ubiquinone oxidoreductase subunit A12

mammalian protein found in Homo sapiens

CI-B17.2
NADH-ubiquinone oxidoreductase subunit B17.2
13 kDa differentiation-associated protein
Complex I-B17.2
NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 12
NDUFA12
complex I B17.2 subunit
CIB17.2
NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 12

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Statements

1 reference

13 November 2019

NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 12

1 reference

stated in

InterPro Release 71.0

reference URL

http://www.ebi.ac.uk/interpro/protein/Q9UI09

1 reference

13 November 2019

1 reference

13 November 2019

electron transfer activity

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9UI09

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9UI09

2 references

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9UI09

determination method

IDA

mitochondrial respiratory chain complex I

3 references

24 April 2018

Cyclin B1/Cdk1 coordinates mitochondrial respiration for cell-cycle G2/M progression

GOA

curator

Critical Assessment of Protein Function Annotation

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9UI09&geneProductId=UniProtKB:Q9UI09

24 April 2018

Accessory subunits are integral for assembly and function of human mitochondrial complex I.

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9UI09&geneProductId=UniProtKB:Q9UI09

24 April 2018

The subunit composition of the human NADH dehydrogenase obtained by rapid one-step immunopurification

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9UI09&geneProductId=UniProtKB:Q9UI09

determination method

IDA

mitochondrial respiratory chain complex I

4 references

8 April 2019

Cyclin B1/Cdk1 coordinates mitochondrial respiration for cell-cycle G2/M progression

GOA

curator

Critical Assessment of Protein Function Annotation

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9UI09

8 April 2019

Accessory subunits are integral for assembly and function of human mitochondrial complex I.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9UI09

8 April 2019

The subunit composition of the human NADH dehydrogenase obtained by rapid one-step immunopurification

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9UI09

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9UI09

determination method

IBA

biological process

response to oxidative stress

1 reference

24 April 2018

Oxidative damage to mitochondrial complex I due to peroxynitrite: identification of reactive tyrosines by mass spectrometry

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9UI09&geneProductId=UniProtKB:Q9UI09

determination method

IDA

respiratory gaseous exchange by respiratory system

1 reference

8 April 2019

Characterization of the human complex I NDUFB7 and 17.2-kDa cDNAs and mutational analysis of 19 genes of the HP fraction in complex I-deficient-patients

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9UI09

determination method

NAS

mitochondrial respiratory chain complex I assembly

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9UI09

determination method

TAS

mitochondrial ATP synthesis coupled electron transport

1 reference

8 April 2019

Cyclin B1/Cdk1 coordinates mitochondrial respiration for cell-cycle G2/M progression

GOA

curator

Critical Assessment of Protein Function Annotation

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9UI09

determination method

IMP

mitochondrial electron transport, NADH to ubiquinone

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9UI09

determination method

TAS

physically interacts with

1 reference

Open Targets Platform

retrieved

14 August 2023

reference URL

https://platform.opentargets.org/drug/CHEMBL1431

metformin hydrochloride

object has role

reaction inhibitor

1 reference

stated in

Open Targets Platform

retrieved

14 August 2023

reference URL

https://platform.opentargets.org/drug/CHEMBL1703

Identifiers

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

13 November 2019

1 reference

1 reference

1 reference

1 reference

1 reference

1 reference

(Q21123068)

NADH:ubiquinone oxidoreductase subunit A12

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Identifiers

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