(Q21123116)

English

Neuroligin 2

mammalian protein found in Homo sapiens

NLGN2
neuroligin-2

In more languages

Statements

1 reference

13 November 2019

UniProt protein ID

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/Q8NFZ4

Alpha/Beta hydrolase fold

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/Q8NFZ4

auxiliary protein involved in transmembrane transport

1 reference

Transporter Classification Database ID

2 October 2019

based on heuristic

hierarchical database ID heuristic

Carboxylesterase type B

1 reference

based on heuristic

inferred from protein domain or family

Carboxylesterase type B, conserved site, protein family

1 reference

based on heuristic

inferred from protein domain or family

1 reference

13 November 2019

UniProt protein ID

1 reference

13 November 2019

UniProt protein ID

molecular function

carboxylic ester hydrolase activity

determination method

1 reference

23 May 2017

http://www.ebi.ac.uk/QuickGO/GAnnotation?protein=Q8NFZ4

determination method

neurexin family protein binding

determination method

5 references

8 April 2019

Neuroligin expressed in nonneuronal cells triggers presynaptic development in contacting axons

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8NFZ4

determination method

8 April 2019

British Heart Foundation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8NFZ4

determination method

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8NFZ4

determination method

8 April 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8NFZ4

determination method

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8NFZ4

determination method

signaling receptor activity

determination method

1 reference

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8NFZ4

determination method

identical protein binding

determination method

1 reference

8 April 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8NFZ4

determination method

integral component of membrane

determination method

1 reference

8 April 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8NFZ4

determination method

determination method

3 references

8 April 2019

Neuroligin expressed in nonneuronal cells triggers presynaptic development in contacting axons

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8NFZ4

determination method

8 April 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8NFZ4

determination method

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8NFZ4

determination method

determination method

4 references

8 April 2019

British Heart Foundation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8NFZ4

determination method

8 April 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8NFZ4

determination method

8 April 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8NFZ4

determination method

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8NFZ4

determination method

determination method

1 reference

8 April 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8NFZ4

determination method

presynaptic membrane

determination method

1 reference

8 April 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8NFZ4

determination method

plasma membrane

determination method

2 references

integral component of postsynaptic membrane

determination method

1 reference

8 April 2019

British Heart Foundation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8NFZ4

determination method

intracellular anatomical structure

determination method

1 reference

23 May 2017

Gene Ontology Consortium

http://www.ebi.ac.uk/QuickGO/GAnnotation?protein=Q8NFZ4

determination method

spanning component of membrane

determination method

1 reference

8 April 2019

The synaptic protein neuroligin-1 interacts with the amyloid β-peptide. Is there a role in Alzheimer's disease?

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8NFZ4

determination method

glycinergic synapse

determination method

1 reference

8 April 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8NFZ4

determination method

dopaminergic synapse

determination method

1 reference

8 April 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8NFZ4

determination method

GABA-ergic synapse

determination method

1 reference

8 April 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8NFZ4

determination method

symmetric, GABA-ergic, inhibitory synapse

determination method

1 reference

8 April 2019

The synaptic protein neuroligin-1 interacts with the amyloid β-peptide. Is there a role in Alzheimer's disease?

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8NFZ4

determination method

integral component of postsynaptic specialization membrane

determination method

1 reference

8 April 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8NFZ4

determination method

biological process

neuromuscular process controlling balance

determination method

1 reference

8 April 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8NFZ4

determination method

modulation of chemical synaptic transmission

determination method

4 references

8 April 2019

British Heart Foundation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8NFZ4

determination method

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8NFZ4

determination method

8 April 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8NFZ4

determination method

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8NFZ4

determination method

positive regulation of protein localization to synapse

determination method

1 reference

8 April 2019

Calsyntenins function as synaptogenic adhesion molecules in concert with neurexins

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8NFZ4

determination method

locomotory exploration behavior

determination method

1 reference

8 April 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8NFZ4

determination method

cell-cell junction maintenance

determination method

1 reference

8 April 2019

Neuroligin expressed in nonneuronal cells triggers presynaptic development in contacting axons

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8NFZ4

determination method

positive regulation of synaptic vesicle clustering

determination method

1 reference

8 April 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8NFZ4

determination method

sensory perception of pain

determination method

1 reference

8 April 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8NFZ4

determination method

terminal button organization

determination method

1 reference

8 April 2019

British Heart Foundation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8NFZ4

determination method

protein localization to synapse

determination method

positive regulation of insulin secretion

determination method

1 reference

8 April 2019

Transcellular neuroligin-2 interactions enhance insulin secretion and are integral to pancreatic β cell function

Community Assessment of Community Annotation with Ontologies

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8NFZ4

determination method

positive regulation of synapse assembly

determination method

1 reference

8 April 2019

British Heart Foundation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8NFZ4

determination method

inhibitory synapse assembly

determination method

1 reference

8 April 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8NFZ4

determination method

synaptic vesicle endocytosis

determination method

1 reference

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8NFZ4

determination method

postsynaptic membrane assembly

determination method

presynaptic membrane assembly

determination method

cell-cell adhesion

determination method

1 reference

8 April 2019

Neuroligin expressed in nonneuronal cells triggers presynaptic development in contacting axons

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8NFZ4

determination method

postsynaptic specialization assembly

determination method

1 reference

8 April 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8NFZ4

determination method

presynapse assembly

determination method

1 reference

8 April 2019

The synaptic protein neuroligin-1 interacts with the amyloid β-peptide. Is there a role in Alzheimer's disease?

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8NFZ4

determination method

carboxylesterase type B, conserved site

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/Q8NFZ4

carboxylesterase, type B

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/Q8NFZ4

Identifiers

RefSeq protein ID

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

30 May 2020

UniProt protein ID

1 reference

13 November 2019

UniProt protein ID

Ensembl protein ID

ENSP00000492323

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000492323

ENSP00000305288

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000305288

ENSP00000461092

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000461092

ENSP00000461168

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000461168

ENSP00000492198

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000492198

ENSP00000492025

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000492025

PDB structure ID

1 reference

10 November 2015

http://www.uniprot.org/uniprot/Q69ZK9.txt?version=103

Transporter Classification Database ID

2 references

Transporter Classification database

13 March 2020

Transporter Classification database

29 April 2020

Sitelinks

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Wikisource(0 entries)

Wikiversity(0 entries)

Wikivoyage(0 entries)

Wiktionary(0 entries)

Multilingual sites(0 entries)

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