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Phosphodiesterase 7B
mammalian protein found in Homo sapiens
rolipram-insensitive phosphodiesterase type 7
PDE7B
high-affinity cAMP-specific 3',5'-cyclic phosphodiesterase
cAMP-specific 3',5'-cyclic phosphodiesterase 7B
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Statements
instance of
protein
1 reference
stated in
UniProt
retrieved
13 November 2019
UniProt protein ID
Q9NP56
part of
3'5'-cyclic nucleotide phosphodiesterase
1 reference
stated in
InterPro Release 71.0
reference URL
http://www.ebi.ac.uk/interpro/protein/Q9NP56
3'5'-cyclic nucleotide phosphodiesterase, catalytic domain superfamily
1 reference
stated in
InterPro Release 71.0
reference URL
http://www.ebi.ac.uk/interpro/protein/Q9NP56
3'5'-cyclic nucleotide phosphodiesterase, catalytic domain, protein family
1 reference
based on heuristic
inferred from protein domain or family
HD/PDEase domain, protein family
1 reference
based on heuristic
inferred from protein domain or family
3'5'-cyclic nucleotide phosphodiesterase, conserved site, protein family
1 reference
based on heuristic
inferred from protein domain or family
found in taxon
Homo sapiens
1 reference
stated in
UniProt
retrieved
13 November 2019
UniProt protein ID
Q9NP56
encoded by
PDE7B
1 reference
stated in
UniProt
retrieved
13 November 2019
UniProt protein ID
Q9NP56
molecular function
3',5'-cyclic-AMP phosphodiesterase activity
determination method
IEA
TAS
3 references
retrieved
5 June 2018
stated in
GOA
curator
Reactome
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9NP56&geneProductId=UniProtKB:Q9NP56
determination method
TAS
retrieved
5 June 2018
stated in
Cloning and characterization of PDE7B, a cAMP-specific phosphodiesterase
GOA
curator
Proteome Inc.
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9NP56&geneProductId=UniProtKB:Q9NP56
determination method
TAS
retrieved
5 June 2018
stated in
GOA
curator
Ensembl genome database project
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9NP56&geneProductId=UniProtKB:Q9NP56
determination method
IEA
phosphoric diester hydrolase activity
determination method
IEA
1 reference
retrieved
8 April 2019
stated in
GOA
curator
InterPro
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9NP56
determination method
IEA
hydrolase activity
determination method
IEA
1 reference
retrieved
8 April 2019
stated in
GOA
curator
UniProt
UniProt protein ID
Q9NP56
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9NP56
determination method
IEA
3',5'-cyclic-nucleotide phosphodiesterase activity
determination method
IEA
1 reference
retrieved
8 April 2019
stated in
GOA
curator
InterPro
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9NP56
determination method
IEA
metal ion binding
determination method
IEA
1 reference
retrieved
8 April 2019
stated in
GOA
curator
UniProt
UniProt protein ID
Q9NP56
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9NP56
determination method
IEA
3',5'-cyclic-AMP phosphodiesterase activity
determination method
IBA
IEA
TAS
3 references
retrieved
8 April 2019
stated in
Cloning and characterization of PDE7B, a cAMP-specific phosphodiesterase
GOA
curator
Proteome Inc.
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9NP56
determination method
TAS
retrieved
8 April 2019
stated in
GOA
curator
Ensembl genome database project
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9NP56
determination method
IEA
retrieved
8 April 2019
stated in
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
GOA
curator
GO Central
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9NP56
determination method
IBA
cell component
cytosol
determination method
TAS
1 reference
retrieved
8 April 2019
stated in
GOA
curator
Reactome
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9NP56
determination method
TAS
biological process
cAMP catabolic process
determination method
IEA
1 reference
retrieved
8 April 2019
stated in
GOA
curator
UniProt
UniProt protein ID
Q9NP56
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9NP56
determination method
IEA
signal transduction
determination method
IEA
TAS
2 references
retrieved
8 April 2019
stated in
Identification of human PDE7B, a cAMP-specific phosphodiesterase
GOA
curator
Proteome Inc.
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9NP56
determination method
TAS
retrieved
8 April 2019
stated in
GOA
curator
InterPro
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9NP56
determination method
IEA
chemical synaptic transmission
determination method
TAS
1 reference
retrieved
8 April 2019
stated in
Identification of human PDE7B, a cAMP-specific phosphodiesterase
GOA
curator
Proteome Inc.
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9NP56
determination method
TAS
G protein-coupled receptor signaling pathway
determination method
TAS
1 reference
retrieved
8 April 2019
stated in
GOA
curator
Reactome
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9NP56
determination method
TAS
physically interacts with
brl-50481
has use
enzyme inhibitor
1 reference
stated in
IUPHAR/BPS Guide to PHARMACOLOGY
Guide to Pharmacology Ligand ID
5154
language of work or name
English
retrieved
17 August 2016
dipyridamole
has use
enzyme inhibitor
1 reference
stated in
IUPHAR/BPS Guide to PHARMACOLOGY
Guide to Pharmacology Ligand ID
4807
language of work or name
English
retrieved
17 August 2016
SCH-51866
has use
enzyme inhibitor
1 reference
stated in
IUPHAR/BPS Guide to PHARMACOLOGY
Guide to Pharmacology Ligand ID
5270
language of work or name
English
retrieved
17 August 2016
flavoxate hydrochloride
object has role
reaction inhibitor
1 reference
stated in
Open Targets Platform
retrieved
14 August 2023
reference URL
https://platform.opentargets.org/drug/CHEMBL1200875
exact match
https://identifiers.org/uniprot:Q9NP56
1 reference
stated in
Identifiers.org
UniProt protein ID
Q9NP56
reference URL
https://registry.identifiers.org/registry/uniprot
http://purl.uniprot.org/uniprot/Q9NP56
1 reference
stated in
Identifiers.org
UniProt protein ID
Q9NP56
reference URL
https://registry.identifiers.org/registry/uniprot
https://www.ncbi.nlm.nih.gov/protein/Q9NP56
1 reference
stated in
Identifiers.org
UniProt protein ID
Q9NP56
reference URL
https://registry.identifiers.org/registry/uniprot
has part(s)
3'5'-cyclic nucleotide phosphodiesterase, conserved site
1 reference
stated in
InterPro Release 71.0
reference URL
http://www.ebi.ac.uk/interpro/protein/Q9NP56
3'5'-cyclic nucleotide phosphodiesterase, catalytic domain
1 reference
stated in
InterPro Release 71.0
reference URL
http://www.ebi.ac.uk/interpro/protein/Q9NP56
HD/PDEase domain
1 reference
stated in
InterPro Release 71.0
reference URL
http://www.ebi.ac.uk/interpro/protein/Q9NP56
Identifiers
RefSeq protein ID
NP_061818
1 reference
stated in
NCBI Gene
retrieved
30 May 2020
Entrez Gene ID
27115
UniProt protein ID
Q9NP56
1 reference
stated in
UniProt
retrieved
13 November 2019
UniProt protein ID
Q9NP56
Ensembl protein ID
ENSP00000310661
1 reference
stated in
Ensembl Release 99
Ensembl protein ID
ENSP00000310661
ENSP00000403732
1 reference
stated in
Ensembl Release 99
Ensembl protein ID
ENSP00000403732
ENSP00000482117
1 reference
stated in
Ensembl Release 99
Ensembl protein ID
ENSP00000482117
PDB structure ID
1LXW
1 reference
stated in
Swiss-Prot
UniProt
retrieved
6 January 2016
reference URL
http://www.uniprot.org/uniprot/Q9NP56.txt?version=136
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