Wikidata

(Q21123280)

English

Polo like kinase 3

mammalian protein found in Homo sapiens

  • FGF-inducible kinase
  • serine/threonine-protein kinase PLK3
  • Polo-like kinase 3
  • cytokine-inducible serine/threonine-protein kinase
  • PLK-3
  • proliferation-related kinase
  • PLK3
In more languages

Statements

molecular function
protein serine/threonine kinase activity
determination method
IDA
IEA
TAS
12 references
retrieved
7 November 2018
stated in
GOA
curator
Reactome
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9H4B4&geneProductId=UniProtKB:Q9H4B4
determination method
TAS
retrieved
7 November 2018
stated in
Prk, a cytokine-inducible human protein serine/threonine kinase whose expression appears to be down-regulated in lung carcinomas
GOA
curator
Proteome Inc.
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9H4B4&geneProductId=UniProtKB:Q9H4B4
determination method
TAS
retrieved
7 November 2018
stated in
GOA
curator
UniProt
UniProt protein ID
Q9H4B4
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9H4B4&geneProductId=UniProtKB:Q9H4B4
determination method
IEA
retrieved
7 November 2018
stated in
GOA
curator
InterPro
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9H4B4&geneProductId=UniProtKB:Q9H4B4
determination method
IEA
retrieved
7 November 2018
stated in
Cdc25C phosphorylation on serine 191 by Plk3 promotes its nuclear translocation
GOA
curator
UniProt
UniProt protein ID
Q9H4B4
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9H4B4&geneProductId=UniProtKB:Q9H4B4
determination method
IDA
retrieved
7 November 2018
stated in
Priming phosphorylation of Chk2 by polo-like kinase 3 (Plk3) mediates its full activation by ATM and a downstream checkpoint in response to DNA damage
GOA
curator
UniProt
UniProt protein ID
Q9H4B4
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9H4B4&geneProductId=UniProtKB:Q9H4B4
determination method
IDA
retrieved
7 November 2018
stated in
Hyperosmotic stress-induced ATF-2 activation through Polo-like kinase 3 in human corneal epithelial cells
GOA
curator
UniProt
UniProt protein ID
Q9H4B4
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9H4B4&geneProductId=UniProtKB:Q9H4B4
determination method
IDA
retrieved
7 November 2018
stated in
Plk3 functions as an essential component of the hypoxia regulatory pathway by direct phosphorylation of HIF-1alpha
GOA
curator
UniProt
UniProt protein ID
Q9H4B4
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9H4B4&geneProductId=UniProtKB:Q9H4B4
determination method
IDA
retrieved
7 November 2018
stated in
Absence of polo-like kinase 3 in mice stabilizes Cdc25A after DNA damage but is not sufficient to produce tumors
GOA
curator
UniProt
UniProt protein ID
Q9H4B4
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9H4B4&geneProductId=UniProtKB:Q9H4B4
determination method
IDA
retrieved
7 November 2018
stated in
Bcl-xL phosphorylation at Ser49 by polo kinase 3 during cell cycle progression and checkpoints
GOA
curator
UniProt
UniProt protein ID
Q9H4B4
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9H4B4&geneProductId=UniProtKB:Q9H4B4
determination method
IDA
retrieved
7 November 2018
stated in
Reactive oxygen species-induced phosphorylation of p53 on serine 20 is mediated in part by polo-like kinase-3
GOA
curator
UniProt
UniProt protein ID
Q9H4B4
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9H4B4&geneProductId=UniProtKB:Q9H4B4
determination method
IDA
retrieved
7 November 2018
stated in
Plk3 interacts with and specifically phosphorylates VRK1 in Ser342, a downstream target in a pathway that induces Golgi fragmentation
GOA
curator
UniProt
UniProt protein ID
Q9H4B4
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9H4B4&geneProductId=UniProtKB:Q9H4B4
determination method
IDA
protein binding
determination method
IPI
13 references
retrieved
8 April 2019
stated in
Cdc25C phosphorylation on serine 191 by Plk3 promotes its nuclear translocation
GOA
curator
UniProt
UniProt protein ID
Q9H4B4
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9H4B4
determination method
IPI
retrieved
8 April 2019
stated in
Calcium- and integrin-binding protein 1 regulates microtubule organization and centrosome segregation through polo like kinase 3 during cell cycle progression
GOA
curator
UniProt
UniProt protein ID
Q9H4B4
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9H4B4
determination method
IPI
retrieved
8 April 2019
stated in
Priming phosphorylation of Chk2 by polo-like kinase 3 (Plk3) mediates its full activation by ATM and a downstream checkpoint in response to DNA damage
GOA
curator
UniProt
UniProt protein ID
Q9H4B4
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9H4B4
determination method
IPI
retrieved
8 April 2019
stated in
Polo-like kinase 3 is Golgi localized and involved in regulating Golgi fragmentation during the cell cycle
GOA
curator
UniProt
UniProt protein ID
Q9H4B4
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9H4B4
determination method
IPI
retrieved
8 April 2019
stated in
Absence of polo-like kinase 3 in mice stabilizes Cdc25A after DNA damage but is not sufficient to produce tumors
GOA
curator
UniProt
UniProt protein ID
Q9H4B4
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9H4B4
determination method
IPI
retrieved
8 April 2019
stated in
Hyperosmotic stress-induced ATF-2 activation through Polo-like kinase 3 in human corneal epithelial cells
GOA
curator
UniProt
UniProt protein ID
Q9H4B4
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9H4B4
determination method
IPI
retrieved
8 April 2019
stated in
Plk3 inhibits pro-apoptotic activity of p73 through physical interaction and phosphorylation
GOA
curator
UniProt
UniProt protein ID
Q9H4B4
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9H4B4
determination method
IPI
retrieved
8 April 2019
stated in
Bcl-xL phosphorylation at Ser49 by polo kinase 3 during cell cycle progression and checkpoints
GOA
curator
UniProt
UniProt protein ID
Q9H4B4
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9H4B4
determination method
IPI
retrieved
8 April 2019
stated in
Plk3 functions as an essential component of the hypoxia regulatory pathway by direct phosphorylation of HIF-1alpha
GOA
curator
UniProt
UniProt protein ID
Q9H4B4
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9H4B4
determination method
IPI
retrieved
8 April 2019
stated in
Calcium- and integrin-binding protein 1 regulates endomitosis and its interaction with Polo-like kinase 3 is enhanced in endomitotic Dami cells
GOA
curator
UniProt
UniProt protein ID
Q9H4B4
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9H4B4
determination method
IPI
retrieved
8 April 2019
stated in
A proteome-scale map of the human interactome network
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9H4B4
determination method
IPI
retrieved
8 April 2019
stated in
Protein microarray analysis identifies human cellular prion protein interactors
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9H4B4
determination method
IPI
retrieved
8 April 2019
stated in
Plk3 interacts with and specifically phosphorylates VRK1 in Ser342, a downstream target in a pathway that induces Golgi fragmentation
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9H4B4
determination method
IPI
protein serine/threonine kinase activity
determination method
IBA
IDA
IEA
TAS
13 references
retrieved
8 April 2019
stated in
GOA
curator
Reactome
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9H4B4
determination method
TAS
retrieved
8 April 2019
stated in
Prk, a cytokine-inducible human protein serine/threonine kinase whose expression appears to be down-regulated in lung carcinomas
GOA
curator
Proteome Inc.
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9H4B4
determination method
TAS
retrieved
8 April 2019
stated in
GOA
curator
UniProt
UniProt protein ID
Q9H4B4
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9H4B4
determination method
IEA
retrieved
8 April 2019
stated in
GOA
curator
InterPro
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9H4B4
determination method
IEA
retrieved
8 April 2019
stated in
Cdc25C phosphorylation on serine 191 by Plk3 promotes its nuclear translocation
GOA
curator
UniProt
UniProt protein ID
Q9H4B4
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9H4B4
determination method
IDA
retrieved
8 April 2019
stated in
Priming phosphorylation of Chk2 by polo-like kinase 3 (Plk3) mediates its full activation by ATM and a downstream checkpoint in response to DNA damage
GOA
curator
UniProt
UniProt protein ID
Q9H4B4
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9H4B4
determination method
IDA
retrieved
8 April 2019
stated in
Absence of polo-like kinase 3 in mice stabilizes Cdc25A after DNA damage but is not sufficient to produce tumors
GOA
curator
UniProt
UniProt protein ID
Q9H4B4
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9H4B4
determination method
IDA
retrieved
8 April 2019
stated in
Plk3 interacts with and specifically phosphorylates VRK1 in Ser342, a downstream target in a pathway that induces Golgi fragmentation
GOA
curator
UniProt
UniProt protein ID
Q9H4B4
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9H4B4
determination method
IDA
retrieved
8 April 2019
stated in
Hyperosmotic stress-induced ATF-2 activation through Polo-like kinase 3 in human corneal epithelial cells
GOA
curator
UniProt
UniProt protein ID
Q9H4B4
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9H4B4
determination method
IDA
retrieved
8 April 2019
stated in
Bcl-xL phosphorylation at Ser49 by polo kinase 3 during cell cycle progression and checkpoints
GOA
curator
UniProt
UniProt protein ID
Q9H4B4
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9H4B4
determination method
IDA
retrieved
8 April 2019
stated in
Plk3 functions as an essential component of the hypoxia regulatory pathway by direct phosphorylation of HIF-1alpha
GOA
curator
UniProt
UniProt protein ID
Q9H4B4
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9H4B4
determination method
IDA
retrieved
8 April 2019
stated in
Reactive oxygen species-induced phosphorylation of p53 on serine 20 is mediated in part by polo-like kinase-3
GOA
curator
UniProt
UniProt protein ID
Q9H4B4
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9H4B4
determination method
IDA
retrieved
8 April 2019
stated in
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
GOA
curator
GO Central
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9H4B4
determination method
IBA
cell component
biological process

Identifiers

 
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