(Q21123880)

English

SHOC2 leucine rich repeat scaffold protein

mammalian protein found in Homo sapiens

Protein sur-8 homolog
soc-2 suppressor of clear homolog
SHOC2
leucine-rich repeat protein SHOC-2
Protein soc-2 homolog

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Statements

1 reference

13 November 2019

Leucine-rich repeat domain superfamily

1 reference

stated in

InterPro Release 71.0

reference URL

http://www.ebi.ac.uk/interpro/protein/Q9UQ13

Leucine-rich repeat, typical subtype, protein family

1 reference

based on heuristic

inferred from protein domain or family

Leucine-rich repeat, protein family

1 reference

based on heuristic

inferred from protein domain or family

1 reference

13 November 2019

1 reference

13 November 2019

protein phosphatase 1 binding

1 reference

8 April 2019

A Novel SHOC2 Variant in Rasopathy

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9UQ13

determination method

IDA

protein phosphatase regulator activity

1 reference

8 April 2019

A phosphatase holoenzyme comprised of Shoc2/Sur8 and the catalytic subunit of PP1 functions as an M-Ras effector to modulate Raf activity

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9UQ13

determination method

TAS

protein phosphatase binding

1 reference

8 April 2019

A phosphatase holoenzyme comprised of Shoc2/Sur8 and the catalytic subunit of PP1 functions as an M-Ras effector to modulate Raf activity

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9UQ13

1 reference

8 April 2019

A Novel SHOC2 Variant in Rasopathy

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9UQ13

determination method

IPI

protein serine/threonine phosphatase activity

1 reference

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9UQ13

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9UQ13

4 references

8 April 2019

soc-2 encodes a leucine-rich repeat protein implicated in fibroblast growth factor receptor signaling

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9UQ13

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9UQ13

8 April 2019

A Novel SHOC2 Variant in Rasopathy

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9UQ13

8 April 2019

Mutation of SHOC2 promotes aberrant protein N-myristoylation and causes Noonan-like syndrome with loose anagen hair

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9UQ13

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9UQ13

1 reference

27 February 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9UQ13&geneProductId=UniProtKB:Q9UQ13

determination method

IBA

photoreceptor inner segment

1 reference

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9UQ13

determination method

IBA

photoreceptor outer segment membrane

1 reference

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9UQ13

determination method

IBA

biological process

fibroblast growth factor receptor signaling pathway

1 reference

8 April 2019

soc-2 encodes a leucine-rich repeat protein implicated in fibroblast growth factor receptor signaling

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9UQ13

determination method

NAS

positive regulation of Ras protein signal transduction

determination method

IMP

Ras protein signal transduction

1 reference

8 April 2019

SUR-8, a conserved Ras-binding protein with leucine-rich repeats, positively regulates Ras-mediated signaling in C. elegans

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9UQ13

determination method

NAS

regulation of phosphoprotein phosphatase activity

1 reference

8 April 2019

Gene Ontology Consortium

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9UQ13

determination method

IEA

protein dephosphorylation

1 reference

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9UQ13

determination method

IBA

has part(s)

leucine-rich repeat, typical subtype

1 reference

stated in

InterPro Release 71.0

reference URL

http://www.ebi.ac.uk/interpro/protein/Q9UQ13

Leucine-rich repeat

1 reference

stated in

InterPro Release 71.0

reference URL

http://www.ebi.ac.uk/interpro/protein/Q9UQ13

Identifiers

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

13 November 2019

1 reference

1 reference

1 reference

(Q21123880)

SHOC2 leucine rich repeat scaffold protein

Statements

Identifiers

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