(Q21123963)

http://www.ebi.ac.uk/interpro/protein/P09544

Wnt protein, conserved site, protein family

1 reference

based on heuristic

inferred from protein domain or family

1 reference

13 November 2019

1 reference

13 November 2019

signaling receptor binding

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P09544

1 reference

8 April 2019

Human frizzled 1 interacts with transforming Wnts to transduce a TCF dependent transcriptional response

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P09544

1 reference

8 April 2019

Interaction of frizzled related protein (FRP) with Wnt ligands and the frizzled receptor suggests alternative mechanisms for FRP inhibition of Wnt signaling

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P09544

Human frizzled 1 interacts with transforming Wnts to transduce a TCF dependent transcriptional response

IPI

receptor ligand activity

3 references

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P09544

8 April 2019

Identification of WNT/beta-CATENIN signaling pathway components in human cumulus cells

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P09544

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P09544

4 references

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P09544

8 April 2019

Overexpression of Wnt-2 in colorectal cancers

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P09544

8 April 2019

Identification of WNT/beta-CATENIN signaling pathway components in human cumulus cells

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P09544

8 April 2019

A positive feedback loop involving Gcm1 and Fzd5 directs chorionic branching morphogenesis in the placenta

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P09544

1 reference

10 September 2018

The proinvasive activity of Wnt-2 is mediated through a noncanonical Wnt pathway coupled to GSK-3beta and c-Jun/AP-1 signaling

http://www.ebi.ac.uk/QuickGO/annotations?protein=P09544&geneProductId=UniProtKB:P09544

1 reference

8 April 2019

Human frizzled 1 interacts with transforming Wnts to transduce a TCF dependent transcriptional response

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P09544

1 reference

24 April 2018

Identification of WNT/beta-CATENIN signaling pathway components in human cumulus cells

http://www.ebi.ac.uk/QuickGO/annotations?protein=P09544&geneProductId=UniProtKB:P09544

4 references

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P09544

8 April 2019

Isolation of a human gene with protein sequence similarity to human and murine int-1 and the Drosophila segment polarity mutant wingless

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P09544

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P09544

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P09544

1 reference

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P09544

extrinsic component of external side of plasma membrane

IBA

1 reference

8 April 2019

Identification of WNT/beta-CATENIN signaling pathway components in human cumulus cells

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P09544

collagen-containing extracellular matrix

1 reference

8 April 2019

The proinvasive activity of Wnt-2 is mediated through a noncanonical Wnt pathway coupled to GSK-3beta and c-Jun/AP-1 signaling

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P09544

positive regulation of mesenchymal cell proliferation

biological process

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P09544

positive regulation of cardiac muscle cell proliferation

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P09544

positive regulation of endothelial cell proliferation

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P09544

mammary gland epithelium development

1 reference

8 April 2019

Differential expression of human Wnt genes 2, 3, 4, and 7B in human breast cell lines and normal and disease states of human breast tissue

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P09544

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P09544

1 reference

8 April 2019

Human frizzled 1 interacts with transforming Wnts to transduce a TCF dependent transcriptional response

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P09544

positive regulation of DNA-binding transcription factor activity

1 reference

8 April 2019

Human frizzled 1 interacts with transforming Wnts to transduce a TCF dependent transcriptional response

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P09544

1 reference

8 April 2019

Wnt signaling in midbrain dopaminergic neuron development and regenerative medicine for Parkinson's disease

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P09544

lens development in camera-type eye

TAS

1 reference

8 April 2019

Expression patterns of Wnt genes during development of an anterior part of the chicken eye

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P09544

cardiac epithelial to mesenchymal transition

ISS

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P09544

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P09544

cellular response to retinoic acid

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P09544

1 reference

8 April 2019

Expression patterns of Wnt genes during development of an anterior part of the chicken eye

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P09544

cellular response to transforming growth factor beta stimulus

ISS

1 reference

8 April 2019

Cooperation between TGF-beta and Wnt pathways during chondrocyte and adipocyte differentiation of human marrow stromal cells

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P09544

positive regulation of epithelial cell proliferation involved in lung morphogenesis

IEP

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P09544

positive regulation of cell population proliferation

1 reference

8 April 2019

Interaction of frizzled related protein (FRP) with Wnt ligands and the frizzled receptor suggests alternative mechanisms for FRP inhibition of Wnt signaling

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P09544

1 reference

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P09544

labyrinthine layer blood vessel development

IBA

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P09544

positive regulation of fibroblast proliferation

1 reference

8 April 2019

Mesenchymal stem cells produce Wnt isoforms and TGF-beta1 that mediate proliferation and procollagen expression by lung fibroblasts

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P09544

atrial cardiac muscle tissue morphogenesis

IMP

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P09544

positive regulation of canonical Wnt signaling pathway

1 reference

21 June 2018

Derivation of sarcomas from mesenchymal stem cells via inactivation of the Wnt pathway

http://www.ebi.ac.uk/QuickGO/annotations?protein=P09544&geneProductId=UniProtKB:P09544

canonical Wnt signaling pathway

IMP

4 references

21 June 2018

Wnt signaling in midbrain dopaminergic neuron development and regenerative medicine for Parkinson's disease

http://www.ebi.ac.uk/QuickGO/annotations?protein=P09544&geneProductId=UniProtKB:P09544

21 June 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=P09544&geneProductId=UniProtKB:P09544

21 June 2018

Wnt2 regulates progenitor proliferation in the developing ventral midbrain

http://www.ebi.ac.uk/QuickGO/annotations?protein=P09544&geneProductId=UniProtKB:P09544

21 June 2018

Interaction of frizzled related protein (FRP) with Wnt ligands and the frizzled receptor suggests alternative mechanisms for FRP inhibition of Wnt signaling

http://www.ebi.ac.uk/QuickGO/annotations?protein=P09544&geneProductId=UniProtKB:P09544

http://www.ebi.ac.uk/QuickGO/annotations?protein=P09544&geneProductId=UniProtKB:P09544

neuron differentiation

1 reference

16 July 2018

midbrain dopaminergic neuron differentiation

ISS

1 reference

8 April 2019

Wnt2 regulates progenitor proliferation in the developing ventral midbrain

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P09544

canonical Wnt signaling pathway involved in midbrain dopaminergic neuron differentiation

1 reference

8 April 2019

Wnt2 regulates progenitor proliferation in the developing ventral midbrain

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P09544

http://www.ebi.ac.uk/QuickGO/annotations?protein=P09544&geneProductId=UniProtKB:P09544

Wnt signaling pathway

5 references

21 June 2018

21 June 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=P09544&geneProductId=UniProtKB:P09544

21 June 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=P09544&geneProductId=UniProtKB:P09544

21 June 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=P09544&geneProductId=UniProtKB:P09544

21 June 2018

Human frizzled 1 interacts with transforming Wnts to transduce a TCF dependent transcriptional response

http://www.ebi.ac.uk/QuickGO/annotations?protein=P09544&geneProductId=UniProtKB:P09544

regulation of signaling receptor activity

1 reference

8 April 2019

Gene Ontology Consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P09544

cell proliferation in midbrain

1 reference

8 April 2019

Wnt2 regulates progenitor proliferation in the developing ventral midbrain

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P09544

http://www.ebi.ac.uk/QuickGO/annotations?protein=P09544&geneProductId=UniProtKB:P09544

Wnt signaling pathway

4 references

16 July 2018

16 July 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=P09544&geneProductId=UniProtKB:P09544

16 July 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=P09544&geneProductId=UniProtKB:P09544

16 July 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=P09544&geneProductId=UniProtKB:P09544

canonical Wnt signaling pathway

6 references

8 April 2019

Wnt signaling in midbrain dopaminergic neuron development and regenerative medicine for Parkinson's disease

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P09544

8 April 2019

Derivation of sarcomas from mesenchymal stem cells via inactivation of the Wnt pathway

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P09544

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P09544

8 April 2019

Human frizzled 1 interacts with transforming Wnts to transduce a TCF dependent transcriptional response

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P09544

8 April 2019

Wnt2 regulates progenitor proliferation in the developing ventral midbrain

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P09544

8 April 2019

Interaction of frizzled related protein (FRP) with Wnt ligands and the frizzled receptor suggests alternative mechanisms for FRP inhibition of Wnt signaling

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P09544

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P09544

Wnt signaling pathway

5 references

8 April 2019

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P09544

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P09544

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P09544

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P09544

Wnt protein, conserved site

IBA

has part(s)

1 reference

stated in

InterPro Release 71.0