(Q21125402)

English

Collectrin, amino acid transport regulator

mammalian protein found in Homo sapiens

collectrin
kidney-specific membrane protein
CLTRN
transmembrane protein 27
TMEM27

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Statements

1 reference

13 November 2019

Peptidase M2, peptidyl-dipeptidase A

1 reference

stated in

InterPro Release 71.0

reference URL

http://www.ebi.ac.uk/interpro/protein/Q9HBJ8

Sodium:neurotransmitter symporter

1 reference

Transporter Classification Database ID

2.A.22.6.3

retrieved

2 October 2019

based on heuristic

hierarchical database ID heuristic

Collectrin domain, protein family

1 reference

based on heuristic

inferred from protein domain or family

1 reference

13 November 2019

1 reference

13 November 2019

peptidyl-dipeptidase activity

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9HBJ8

1 reference

8 April 2019

The HNF-1 target collectrin controls insulin exocytosis by SNARE complex formation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9HBJ8

determination method

IPI

metallopeptidase activity

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9HBJ8

determination method

IEA

protein homodimerization activity

1 reference

8 April 2019

Tmem27 dimerization, deglycosylation, plasma membrane depletion, and the extracellular Phe-Phe motif are negative regulators of cleavage by Bace2.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9HBJ8

1 reference

8 April 2019

The HNF-1 target collectrin controls insulin exocytosis by SNARE complex formation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9HBJ8

determination method

IDA

integral component of membrane

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9HBJ8

determination method

IEA

brush border membrane

1 reference

26 September 2017

Ensembl genome database project

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9HBJ8&geneProductId=UniProtKB:Q9HBJ8

2 references

3 references

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9HBJ8

8 April 2019

Bace2 is a β cell-enriched protease that regulates pancreatic β cell function and mass

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9HBJ8

8 April 2019

Tmem27 dimerization, deglycosylation, plasma membrane depletion, and the extracellular Phe-Phe motif are negative regulators of cleavage by Bace2.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9HBJ8

determination method

IDA

extracellular exosome

1 reference

8 April 2019

Large-scale proteomics and phosphoproteomics of urinary exosomes

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9HBJ8

determination method

HDA

biological process

positive regulation of amino acid transport

1 reference

26 September 2017

Ensembl genome database project

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9HBJ8&geneProductId=UniProtKB:Q9HBJ8

determination method

IEA

positive regulation of SNARE complex assembly

1 reference

8 April 2019

The HNF-1 target collectrin controls insulin exocytosis by SNARE complex formation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9HBJ8

determination method

IDA

positive regulation of insulin secretion involved in cellular response to glucose stimulus

1 reference

8 April 2019

The HNF-1 target collectrin controls insulin exocytosis by SNARE complex formation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9HBJ8

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9HBJ8

determination method

IEA

positive regulation of calcium ion-dependent exocytosis

1 reference

8 April 2019

The HNF-1 target collectrin controls insulin exocytosis by SNARE complex formation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9HBJ8

1 reference

InterPro Release 71.0

reference URL

http://www.ebi.ac.uk/interpro/protein/Q9HBJ8

Identifiers

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

13 November 2019

1 reference

1 reference

Transporter Classification Database ID

2.A.22.6.3

2 references

stated in

Transporter Classification database

retrieved

13 March 2020

stated in

Transporter Classification database

retrieved

29 April 2020

(Q21125402)

Collectrin, amino acid transport regulator

Statements

Identifiers

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