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(Q21125850)
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Polyhomeotic homolog 1
mammalian protein found in Homo sapiens
early development regulatory protein 1
PHC1
polyhomeotic-like protein 1
polyhomeotic-like 1
early development regulator 1 (homolog of polyhomeotic 1)
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Statements
instance of
protein
1 reference
stated in
UniProt
retrieved
13 November 2019
UniProt protein ID
P78364
part of
Sterile alpha motif/pointed domain superfamily
1 reference
stated in
InterPro Release 71.0
reference URL
http://www.ebi.ac.uk/interpro/protein/P78364
FCS-type zinc finger superfamily
1 reference
stated in
InterPro Release 71.0
reference URL
http://www.ebi.ac.uk/interpro/protein/P78364
Zinc finger, FCS-type, protein family
1 reference
based on heuristic
inferred from protein domain or family
Sterile alpha motif domain, protein family
1 reference
based on heuristic
inferred from protein domain or family
found in taxon
Homo sapiens
1 reference
stated in
UniProt
retrieved
13 November 2019
UniProt protein ID
P78364
encoded by
PHC1
1 reference
stated in
UniProt
retrieved
13 November 2019
UniProt protein ID
P78364
molecular function
DNA binding
determination method
IEA
1 reference
retrieved
8 April 2019
stated in
GOA
curator
UniProt
UniProt protein ID
P78364
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P78364
determination method
IEA
zinc ion binding
determination method
IEA
1 reference
retrieved
8 April 2019
stated in
GOA
curator
InterPro
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P78364
determination method
IEA
metal ion binding
determination method
IEA
1 reference
retrieved
8 April 2019
stated in
GOA
curator
UniProt
UniProt protein ID
P78364
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P78364
determination method
IEA
protein binding
determination method
IPI
4 references
retrieved
8 April 2019
stated in
Ubiquitin-specific proteases 7 and 11 modulate Polycomb regulation of the INK4a tumour suppressor
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P78364
determination method
IPI
retrieved
8 April 2019
stated in
Structure of the Polycomb Group Protein PCGF1 in Complex with BCOR Reveals Basis for Binding Selectivity of PCGF Homologs
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P78364
determination method
IPI
retrieved
8 April 2019
stated in
Several distinct polycomb complexes regulate and co-localize on the INK4a tumor suppressor locus
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P78364
determination method
IPI
retrieved
8 April 2019
stated in
A High-Density Map for Navigating the Human Polycomb Complexome
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P78364
determination method
IPI
cell component
PcG protein complex
determination method
IDA
1 reference
retrieved
8 April 2019
stated in
Interaction proteomics analysis of polycomb proteins defines distinct PRC1 complexes in mammalian cells
GOA
curator
UniProt
UniProt protein ID
P78364
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P78364
determination method
IDA
PRC1 complex
determination method
IDA
2 references
retrieved
8 April 2019
stated in
The core of the polycomb repressive complex is compositionally and functionally conserved in flies and humans
GOA
curator
UniProt
UniProt protein ID
P78364
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P78364
determination method
IDA
retrieved
8 April 2019
stated in
Several distinct polycomb complexes regulate and co-localize on the INK4a tumor suppressor locus
GOA
curator
UniProt
UniProt protein ID
P78364
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P78364
determination method
IDA
nucleus
determination method
IDA
IEA
TAS
5 references
retrieved
8 April 2019
stated in
Identification and characterization of interactions between the vertebrate polycomb-group protein BMI1 and human homologs of polyhomeotic
GOA
curator
Proteome Inc.
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P78364
determination method
TAS
retrieved
8 April 2019
stated in
GOA
curator
UniProt
UniProt protein ID
P78364
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P78364
determination method
IEA
retrieved
8 April 2019
stated in
GOA
curator
InterPro
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P78364
determination method
IEA
retrieved
8 April 2019
stated in
Interaction proteomics analysis of polycomb proteins defines distinct PRC1 complexes in mammalian cells
GOA
curator
UniProt
UniProt protein ID
P78364
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P78364
determination method
IDA
retrieved
8 April 2019
stated in
GOA
curator
Human Protein Atlas
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P78364
determination method
IDA
nucleoplasm
determination method
TAS
1 reference
retrieved
8 April 2019
stated in
GOA
curator
Reactome
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P78364
determination method
TAS
biological process
multicellular organism development
determination method
IEA
1 reference
retrieved
8 April 2019
stated in
GOA
curator
UniProt
UniProt protein ID
P78364
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P78364
determination method
IEA
histone ubiquitination
determination method
IDA
1 reference
retrieved
8 April 2019
stated in
Mutation in PHC1 implicates chromatin remodeling in primary microcephaly pathogenesis
GOA
curator
UniProt
UniProt protein ID
P78364
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P78364
determination method
IDA
negative regulation of G0 to G1 transition
determination method
TAS
1 reference
retrieved
8 April 2019
stated in
GOA
curator
Reactome
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P78364
determination method
TAS
has part(s)
Zinc finger, FCS-type
1 reference
stated in
InterPro Release 71.0
reference URL
http://www.ebi.ac.uk/interpro/protein/P78364
sterile alpha motif domain
1 reference
stated in
InterPro Release 71.0
reference URL
http://www.ebi.ac.uk/interpro/protein/P78364
Identifiers
RefSeq protein ID
NP_004417
1 reference
stated in
NCBI Gene
retrieved
30 May 2020
Entrez Gene ID
1911
XP_005253391
1 reference
stated in
NCBI Gene
retrieved
30 May 2020
Entrez Gene ID
1911
XP_011518901
1 reference
stated in
NCBI Gene
retrieved
30 May 2020
Entrez Gene ID
1911
XP_011518902
1 reference
stated in
NCBI Gene
retrieved
30 May 2020
Entrez Gene ID
1911
XP_011518905
1 reference
stated in
NCBI Gene
retrieved
30 May 2020
Entrez Gene ID
1911
XP_016874444
1 reference
stated in
NCBI Gene
retrieved
30 May 2020
Entrez Gene ID
1911
XP_016874445
1 reference
stated in
NCBI Gene
retrieved
30 May 2020
Entrez Gene ID
1911
XP_016874446
1 reference
stated in
NCBI Gene
retrieved
30 May 2020
Entrez Gene ID
1911
XP_016874447
1 reference
stated in
NCBI Gene
retrieved
30 May 2020
Entrez Gene ID
1911
UniProt protein ID
P78364
1 reference
stated in
UniProt
retrieved
13 November 2019
UniProt protein ID
P78364
Ensembl protein ID
ENSP00000437659
1 reference
stated in
Ensembl Release 99
Ensembl protein ID
ENSP00000437659
ENSP00000440674
1 reference
stated in
Ensembl Release 99
Ensembl protein ID
ENSP00000440674
ENSP00000399194
1 reference
stated in
Ensembl Release 99
Ensembl protein ID
ENSP00000399194
ENSP00000437459
1 reference
stated in
Ensembl Release 99
Ensembl protein ID
ENSP00000437459
ENSP00000437645
1 reference
stated in
Ensembl Release 99
Ensembl protein ID
ENSP00000437645
ENSP00000437654
1 reference
stated in
Ensembl Release 99
Ensembl protein ID
ENSP00000437654
ENSP00000443676
1 reference
stated in
Ensembl Release 99
Ensembl protein ID
ENSP00000443676
ENSP00000444308
1 reference
stated in
Ensembl Release 99
Ensembl protein ID
ENSP00000444308
ENSP00000445307
1 reference
stated in
Ensembl Release 99
Ensembl protein ID
ENSP00000445307
ENSP00000445939
1 reference
stated in
Ensembl Release 99
Ensembl protein ID
ENSP00000445939
ENSP00000446388
1 reference
stated in
Ensembl Release 99
Ensembl protein ID
ENSP00000446388
PDB structure ID
2L8E
1 reference
stated in
UniProt
UniProt protein ID
P78364
retrieved
9 August 2016
language of work or name
English
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