(Q21125899)

PLC-like phosphodiesterase, TIM beta/alpha-barrel domain superfamily

1 reference

C2 domain superfamily

1 reference

Ras guanine nucleotide exchange factor domain superfamily

1 reference

1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase epsilon-1

1 reference

EF-hand domain pair

1 reference

Ras-associating (RA) domain, protein family

1 reference

Ras guanine-nucleotide exchange factors catalytic domain, protein family

1 reference

C2 domain, protein family

1 reference

Phosphatidylinositol-specific phospholipase C, X domain, protein family

1 reference

Phospholipase C, phosphatidylinositol-specific, Y domain, protein family

1 reference

Phosphoinositide-specific phospholipase C, EF-hand-like domain, protein family

1 reference

guanyl-nucleotide exchange factor activity

1 reference

13 November 2019

1 reference

13 November 2019

3 references

8 April 2019

A novel bifunctional phospholipase c that is regulated by Galpha 12 and stimulates the Ras/mitogen-activated protein kinase pathway

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9P212

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9P212

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9P212

signal transducer activity

1 reference

24 April 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9P212&geneProductId=UniProtKB:Q9P212

1 reference

24 April 2018

Regulation of a novel human phospholipase C, PLCepsilon, through membrane targeting by Ras

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9P212&geneProductId=UniProtKB:Q9P212

phosphoric diester hydrolase activity

IPI

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9P212

1 reference

8 April 2019

Regulation of a novel human phospholipase C, PLCepsilon, through membrane targeting by Ras

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9P212

A novel bifunctional phospholipase c that is regulated by Galpha 12 and stimulates the Ras/mitogen-activated protein kinase pathway

IPI

phospholipase C activity

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9P212

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9P212

phosphatidylinositol phospholipase C activity

5 references

24 April 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9P212&geneProductId=UniProtKB:Q9P212

24 April 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9P212&geneProductId=UniProtKB:Q9P212

24 April 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9P212&geneProductId=UniProtKB:Q9P212

24 April 2018

Regulation of a novel human phospholipase C, PLCepsilon, through membrane targeting by Ras

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9P212&geneProductId=UniProtKB:Q9P212

24 April 2018

A novel bifunctional phospholipase c that is regulated by Galpha 12 and stimulates the Ras/mitogen-activated protein kinase pathway

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9P212&geneProductId=UniProtKB:Q9P212

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9P212

phosphatidylinositol phospholipase C activity

6 references

7 November 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9P212&geneProductId=UniProtKB:Q9P212

7 November 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9P212&geneProductId=UniProtKB:Q9P212

7 November 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9P212&geneProductId=UniProtKB:Q9P212

7 November 2018

A novel bifunctional phospholipase c that is regulated by Galpha 12 and stimulates the Ras/mitogen-activated protein kinase pathway

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9P212&geneProductId=UniProtKB:Q9P212

7 November 2018

Regulation of a novel human phospholipase C, PLCepsilon, through membrane targeting by Ras

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9P212&geneProductId=UniProtKB:Q9P212

7 November 2018

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9P212&geneProductId=UniProtKB:Q9P212

phosphatidylinositol phospholipase C activity

5 references

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9P212

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9P212

8 April 2019

Regulation of a novel human phospholipase C, PLCepsilon, through membrane targeting by Ras

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9P212

8 April 2019

A novel bifunctional phospholipase c that is regulated by Galpha 12 and stimulates the Ras/mitogen-activated protein kinase pathway

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9P212

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9P212

3 references

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9P212

8 April 2019

Regulation of a novel human phospholipase C, PLCepsilon, through membrane targeting by Ras

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9P212

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9P212

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9P212

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9P212

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9P212

3 references

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9P212

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9P212

8 April 2019

Regulation of a novel human phospholipase C, PLCepsilon, through membrane targeting by Ras

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9P212

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9P212

intracellular signal transduction

biological process

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9P212

epidermal growth factor receptor signaling pathway

1 reference

8 April 2019

Regulation of a novel human phospholipase C, PLCepsilon, through membrane targeting by Ras

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9P212

regulation of G protein-coupled receptor signaling pathway

1 reference

8 April 2019

A novel bifunctional phospholipase c that is regulated by Galpha 12 and stimulates the Ras/mitogen-activated protein kinase pathway

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9P212

regulation of smooth muscle contraction

1 reference

8 April 2019

A novel bifunctional phospholipase c that is regulated by Galpha 12 and stimulates the Ras/mitogen-activated protein kinase pathway

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9P212

positive regulation of cytosolic calcium ion concentration

1 reference

8 April 2019

A novel bifunctional phospholipase c that is regulated by Galpha 12 and stimulates the Ras/mitogen-activated protein kinase pathway

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9P212

small GTPase mediated signal transduction

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9P212

regulation of Ras protein signal transduction

1 reference

8 April 2019

A novel bifunctional phospholipase c that is regulated by Galpha 12 and stimulates the Ras/mitogen-activated protein kinase pathway

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9P212

Positional cloning uncovers mutations in PLCE1 responsible for a nephrotic syndrome variant that may be reversible

glomerulus development

1 reference

8 April 2019

GOA

curator

HUGO Gene Nomenclature Committee

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9P212

inositol phosphate metabolic process

IMP

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9P212

diacylglycerol biosynthetic process

1 reference

8 April 2019

A novel bifunctional phospholipase c that is regulated by Galpha 12 and stimulates the Ras/mitogen-activated protein kinase pathway

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9P212

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9P212

lipid catabolic process

1 reference

8 April 2019

phospholipase C-activating G protein-coupled receptor signaling pathway

1 reference

8 April 2019

A novel bifunctional phospholipase c that is regulated by Galpha 12 and stimulates the Ras/mitogen-activated protein kinase pathway

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9P212

cytoskeleton organization

1 reference

8 April 2019

A novel bifunctional phospholipase c that is regulated by Galpha 12 and stimulates the Ras/mitogen-activated protein kinase pathway

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9P212

regulation of cell growth

1 reference

8 April 2019

A novel bifunctional phospholipase c that is regulated by Galpha 12 and stimulates the Ras/mitogen-activated protein kinase pathway

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9P212

regulation of protein kinase activity

1 reference

8 April 2019

A novel bifunctional phospholipase c that is regulated by Galpha 12 and stimulates the Ras/mitogen-activated protein kinase pathway

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9P212

cell population proliferation

1 reference

8 April 2019

Regulation of a novel human phospholipase C, PLCepsilon, through membrane targeting by Ras

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9P212

inositol phosphate-mediated signaling

1 reference

8 April 2019

A novel bifunctional phospholipase c that is regulated by Galpha 12 and stimulates the Ras/mitogen-activated protein kinase pathway

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9P212

calcium-mediated signaling

Ras protein signal transduction

1 reference

24 April 2018

Regulation of a novel human phospholipase C, PLCepsilon, through membrane targeting by Ras

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9P212&geneProductId=UniProtKB:Q9P212

inositol trisphosphate biosynthetic process

1 reference

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9P212

phosphatidylinositol-mediated signaling

1 reference

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9P212

release of sequestered calcium ion into cytosol

1 reference

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9P212

Phosphoinositide-specific phospholipase C, EF-hand-like domain

has part(s)

1 reference

Phosphatidylinositol-specific phospholipase C, X domain

1 reference

Phospholipase C, phosphatidylinositol-specific, Y domain

1 reference

C2 domain

1 reference

Ras-associating (RA) domain

1 reference

Ras guanine-nucleotide exchange factors catalytic domain

1 reference