Wikidata

(Q21126041)

English

Pre-mRNA processing factor 31

mammalian protein found in Homo sapiens

  • hPrp31
  • U4/U6 small nuclear ribonucleoprotein Prp31
  • PRPF31
  • PRP31 pre-mRNA processing factor 31 homolog
  • Pre-mRNA-processing factor 31
  • protein 61K
  • U4/U6 snRNP 61 kDa protein
  • serologically defined breast cancer antigen NY-BR-99
In more languages

Statements

molecular function
protein binding
determination method
IPI
6 references
retrieved
8 April 2019
stated in
CTNNBL1 is a novel nuclear localization sequence-binding protein that recognizes RNA-splicing factors CDC5L and Prp31
GOA
curator
UniProt
UniProt protein ID
Q8WWY3
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8WWY3
determination method
IPI
retrieved
8 April 2019
stated in
A proteome-scale map of the human interactome network
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8WWY3
determination method
IPI
retrieved
8 April 2019
stated in
Dynamic protein-protein interaction wiring of the human spliceosome
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8WWY3
determination method
IPI
retrieved
8 April 2019
stated in
Widespread macromolecular interaction perturbations in human genetic disorders
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8WWY3
determination method
IPI
retrieved
8 April 2019
stated in
Pooled-matrix protein interaction screens using Barcode Fusion Genetics
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8WWY3
determination method
IPI
retrieved
8 April 2019
stated in
The nuclear cap-binding complex interacts with the U4/U6·U5 tri-snRNP and promotes spliceosome assembly in mammalian cells
GOA
curator
Critical Assessment of Protein Function Annotation
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8WWY3
determination method
IPI
cell component
biological process
mRNA splicing, via spliceosome
determination method
IBA
IC
IDA
IEA
TAS
6 references
retrieved
8 April 2019
stated in
GOA
curator
Reactome
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8WWY3
determination method
TAS
retrieved
8 April 2019
stated in
GOA
curator
InterPro
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8WWY3
determination method
IEA
retrieved
8 April 2019
stated in
Cryo-EM Structure of a Pre-catalytic Human Spliceosome Primed for Activation.
GOA
curator
UniProt
UniProt protein ID
Q8WWY3
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8WWY3
determination method
IDA
retrieved
8 April 2019
stated in
Protein 61K, encoded by a gene (PRPF31) linked to autosomal dominant retinitis pigmentosa, is required for U4/U6*U5 tri-snRNP formation and pre-mRNA splicing
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8WWY3
determination method
IDA
retrieved
8 April 2019
stated in
RNAi knockdown of hPrp31 leads to an accumulation of U4/U6 di-snRNPs in Cajal bodies
GOA
curator
British Heart Foundation
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8WWY3
determination method
IC
retrieved
8 April 2019
stated in
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
GOA
curator
GO Central
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8WWY3
determination method
IBA

Identifiers

 
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