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(Q21126337)
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English
Succinate dehydrogenase complex assembly factor 1
mammalian protein found in Homo sapiens
SDH assembly factor 1
SDHAF1
LYR motif containing 8
LYR motif-containing protein 8
succinate dehydrogenase assembly factor 1, mitochondrial
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Statements
instance of
protein
1 reference
stated in
UniProt
retrieved
13 November 2019
UniProt protein ID
A6NFY7
part of
Complex 1 LYR protein
1 reference
stated in
InterPro Release 71.0
reference URL
http://www.ebi.ac.uk/interpro/protein/A6NFY7
found in taxon
Homo sapiens
1 reference
stated in
UniProt
retrieved
13 November 2019
UniProt protein ID
A6NFY7
encoded by
SDHAF1
1 reference
stated in
UniProt
retrieved
13 November 2019
UniProt protein ID
A6NFY7
molecular function
protein binding
determination method
IPI
3 references
retrieved
8 April 2019
stated in
Cochaperone binding to LYR motifs confers specificity of iron sulfur cluster delivery.
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:A6NFY7
determination method
IPI
retrieved
8 April 2019
stated in
A Single Adaptable Cochaperone-Scaffold Complex Delivers Nascent Iron-Sulfur Clusters to Mammalian Respiratory Chain Complexes I-III.
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:A6NFY7
determination method
IPI
retrieved
8 April 2019
stated in
Disease-Causing SDHAF1 Mutations Impair Transfer of Fe-S Clusters to SDHB
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:A6NFY7
determination method
IPI
cell component
mitochondrion
determination method
IDA
IEA
2 references
retrieved
8 April 2019
stated in
GOA
curator
UniProt
UniProt protein ID
A6NFY7
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:A6NFY7
determination method
IEA
retrieved
8 April 2019
stated in
SDHAF1, encoding a LYR complex-II specific assembly factor, is mutated in SDH-defective infantile leukoencephalopathy
GOA
curator
UniProt
UniProt protein ID
A6NFY7
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:A6NFY7
determination method
IDA
mitochondrial matrix
determination method
IEA
1 reference
retrieved
8 April 2019
stated in
GOA
curator
UniProt
UniProt protein ID
A6NFY7
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:A6NFY7
determination method
IEA
biological process
mitochondrial respiratory chain complex II assembly
determination method
IMP
1 reference
retrieved
8 April 2019
stated in
SDHAF1, encoding a LYR complex-II specific assembly factor, is mutated in SDH-defective infantile leukoencephalopathy
GOA
curator
UniProt
UniProt protein ID
A6NFY7
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:A6NFY7
determination method
IMP
Identifiers
RefSeq protein ID
NP_001036096
1 reference
stated in
NCBI Gene
retrieved
30 May 2020
Entrez Gene ID
644096
UniProt protein ID
A6NFY7
1 reference
stated in
UniProt
retrieved
13 November 2019
UniProt protein ID
A6NFY7
Ensembl protein ID
ENSP00000368165
1 reference
stated in
Ensembl Release 99
Ensembl protein ID
ENSP00000368165
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