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(Q21126457)
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SPO11 initiator of meiotic double stranded breaks
mammalian protein found in Homo sapiens
CT35
cancer/testis antigen 35
meiotic recombination protein SPO11
SPO11 meiotic protein covalently bound to DSB homolog
spermatogenesis associated 43
SPO11
In more languages
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Statements
instance of
protein
1 reference
stated in
UniProt
retrieved
13 November 2019
UniProt protein ID
Q9Y5K1
part of
Winged helix-like DNA-binding domain superfamily
1 reference
stated in
InterPro Release 71.0
reference URL
http://www.ebi.ac.uk/interpro/protein/Q9Y5K1
SPO11
1 reference
stated in
InterPro Release 71.0
reference URL
http://www.ebi.ac.uk/interpro/protein/Q9Y5K1
Spo11/DNA topoisomerase VI subunit A superfamily
1 reference
stated in
InterPro Release 71.0
reference URL
http://www.ebi.ac.uk/interpro/protein/Q9Y5K1
Spo11/DNA topoisomerase VI, subunit A, N-terminal domain, protein family
1 reference
based on heuristic
inferred from protein domain or family
Topoisomerase 6 subunit A/Spo11, TOPRIM domain, protein family
1 reference
based on heuristic
inferred from protein domain or family
Meiosis-specific protein Spo11 family
1 reference
based on heuristic
inferred from protein domain or family
found in taxon
Homo sapiens
1 reference
stated in
UniProt
retrieved
13 November 2019
UniProt protein ID
Q9Y5K1
encoded by
SPO11
1 reference
stated in
UniProt
retrieved
13 November 2019
UniProt protein ID
Q9Y5K1
molecular function
metal ion binding
determination method
IEA
1 reference
retrieved
9 May 2019
stated in
GOA
curator
UniProt
UniProt protein ID
Q9Y5K1
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Y5K1
determination method
IEA
catalytic activity
determination method
IEA
1 reference
retrieved
9 May 2019
stated in
GOA
curator
InterPro
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Y5K1
determination method
IEA
hydrolase activity
determination method
IEA
1 reference
retrieved
9 May 2019
stated in
GOA
curator
UniProt
UniProt protein ID
Q9Y5K1
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Y5K1
determination method
IEA
ATP binding
determination method
IEA
1 reference
retrieved
9 May 2019
stated in
GOA
curator
InterPro
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Y5K1
determination method
IEA
protein binding
determination method
IPI
1 reference
retrieved
9 May 2019
stated in
A DNA topoisomerase VI-like complex initiates meiotic recombination
GOA
curator
UniProt
UniProt protein ID
Q9Y5K1
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Y5K1
determination method
IPI
isomerase activity
determination method
IEA
1 reference
retrieved
9 May 2019
stated in
GOA
curator
UniProt
UniProt protein ID
Q9Y5K1
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Y5K1
determination method
IEA
DNA topoisomerase type II (double strand cut, ATP-hydrolyzing) activity
determination method
IBA
IEA
2 references
retrieved
27 March 2018
stated in
GOA
curator
UniProt
UniProt protein ID
Q9Y5K1
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9Y5K1&geneProductId=UniProtKB:Q9Y5K1
determination method
IEA
retrieved
27 March 2018
stated in
GOA
curator
GO Central
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9Y5K1&geneProductId=UniProtKB:Q9Y5K1
determination method
IBA
endodeoxyribonuclease activity, producing 3'-phosphomonoesters
determination method
IBA
1 reference
retrieved
8 April 2019
stated in
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
GOA
curator
GO Central
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Y5K1
determination method
IBA
DNA binding
determination method
IBA
IEA
TAS
4 references
retrieved
9 May 2019
stated in
Cloning, characterization, and localization of mouse and human SPO11
GOA
curator
Proteome Inc.
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Y5K1
determination method
TAS
retrieved
9 May 2019
stated in
GOA
curator
UniProt
UniProt protein ID
Q9Y5K1
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Y5K1
determination method
IEA
retrieved
9 May 2019
stated in
GOA
curator
InterPro
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Y5K1
determination method
IEA
retrieved
9 May 2019
stated in
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
GOA
curator
GO Central
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Y5K1
determination method
IBA
DNA topoisomerase type II (double strand cut, ATP-hydrolyzing) activity
determination method
IEA
1 reference
retrieved
1 January 2018
stated in
GOA
curator
UniProt
UniProt protein ID
Q9Y5K1
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Y5K1
determination method
IEA
endodeoxyribonuclease activity, producing 3'-phosphomonoesters
determination method
IBA
IEA
2 references
retrieved
9 May 2019
stated in
GOA
curator
InterPro
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Y5K1
determination method
IEA
retrieved
9 May 2019
stated in
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
GOA
curator
GO Central
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Y5K1
determination method
IBA
cell component
chromosome
determination method
IEA
1 reference
retrieved
9 May 2019
stated in
GOA
curator
InterPro
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Y5K1
determination method
IEA
telomere
determination method
IEA
1 reference
retrieved
9 May 2019
stated in
GOA
curator
Ensembl genome database project
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Y5K1
determination method
IEA
nucleus
determination method
IEA
1 reference
retrieved
9 May 2019
stated in
GOA
curator
UniProt
UniProt protein ID
Q9Y5K1
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Y5K1
determination method
IEA
nuclear chromosome
determination method
IBA
1 reference
retrieved
1 January 2018
stated in
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
GOA
curator
GO Central
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9Y5K1&geneProductId=UniProtKB:Q9Y5K1
determination method
IBA
biological process
protein localization to chromosome
determination method
IEA
1 reference
retrieved
9 May 2019
stated in
GOA
curator
Ensembl genome database project
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Y5K1
determination method
IEA
female gamete generation
determination method
TAS
1 reference
retrieved
9 May 2019
stated in
Cloning, characterization, and localization of mouse and human SPO11
GOA
curator
Proteome Inc.
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Y5K1
determination method
TAS
meiotic telomere clustering
determination method
IEA
1 reference
retrieved
9 May 2019
stated in
GOA
curator
Ensembl genome database project
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Y5K1
determination method
IEA
male meiosis I
determination method
IEA
1 reference
retrieved
9 May 2019
stated in
GOA
curator
Ensembl genome database project
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Y5K1
determination method
IEA
DNA metabolic process
determination method
IEA
1 reference
retrieved
9 May 2019
stated in
GOA
curator
InterPro
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Y5K1
determination method
IEA
DNA catabolic process, endonucleolytic
determination method
IEA
1 reference
retrieved
9 May 2019
stated in
GOA
curator
InterPro
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Y5K1
determination method
IEA
oogenesis
determination method
IEA
1 reference
retrieved
9 May 2019
stated in
GOA
curator
Ensembl genome database project
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Y5K1
determination method
IEA
homologous chromosome pairing at meiosis
determination method
IEA
1 reference
retrieved
9 May 2019
stated in
GOA
curator
Ensembl genome database project
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Y5K1
determination method
IEA
meiosis
determination method
IEA
1 reference
retrieved
9 May 2019
stated in
GOA
curator
UniProt
UniProt protein ID
Q9Y5K1
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Y5K1
determination method
IEA
synaptonemal complex assembly
determination method
IEA
1 reference
retrieved
9 May 2019
stated in
GOA
curator
Ensembl genome database project
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Y5K1
determination method
IEA
spermatogenesis
determination method
TAS
1 reference
retrieved
9 May 2019
stated in
Cloning, characterization, and localization of mouse and human SPO11
GOA
curator
Proteome Inc.
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Y5K1
determination method
TAS
spermatid development
determination method
IEA
1 reference
retrieved
9 May 2019
stated in
GOA
curator
Ensembl genome database project
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Y5K1
determination method
IEA
ovarian follicle development
determination method
IEA
1 reference
retrieved
9 May 2019
stated in
GOA
curator
Ensembl genome database project
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Y5K1
determination method
IEA
meiotic DNA double-strand break processing
determination method
IBA
1 reference
retrieved
9 May 2019
stated in
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
GOA
curator
GO Central
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Y5K1
determination method
IBA
meiotic DNA double-strand break formation
determination method
IBA
1 reference
retrieved
9 May 2019
stated in
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
GOA
curator
GO Central
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Y5K1
determination method
IBA
reciprocal meiotic recombination
determination method
IBA
IEA
TAS
4 references
retrieved
9 May 2019
stated in
Cloning, characterization, and localization of mouse and human SPO11
GOA
curator
Proteome Inc.
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Y5K1
determination method
TAS
retrieved
9 May 2019
stated in
GOA
curator
InterPro
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Y5K1
determination method
IEA
retrieved
9 May 2019
stated in
GOA
curator
Ensembl genome database project
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Y5K1
determination method
IEA
retrieved
9 May 2019
stated in
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
GOA
curator
GO Central
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Y5K1
determination method
IBA
double-strand break repair involved in meiotic recombination
determination method
IEA
1 reference
retrieved
9 May 2019
stated in
GOA
curator
Ensembl genome database project
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Y5K1
determination method
IEA
has part(s)
Spo11/DNA topoisomerase VI, subunit A, N-terminal
1 reference
stated in
InterPro Release 71.0
reference URL
http://www.ebi.ac.uk/interpro/protein/Q9Y5K1
Meiosis-specific protein Spo11 domain
1 reference
stated in
InterPro Release 71.0
reference URL
http://www.ebi.ac.uk/interpro/protein/Q9Y5K1
Topoisomerase 6 subunit A/Spo11, TOPRIM domain
1 reference
stated in
InterPro Release 71.0
reference URL
http://www.ebi.ac.uk/interpro/protein/Q9Y5K1
Identifiers
RefSeq protein ID
NP_036576
1 reference
stated in
NCBI Gene
retrieved
30 May 2020
Entrez Gene ID
23626
NP_937998
1 reference
stated in
NCBI Gene
retrieved
30 May 2020
Entrez Gene ID
23626
XP_005260436
1 reference
stated in
NCBI Gene
retrieved
30 May 2020
Entrez Gene ID
23626
XP_005260437
1 reference
stated in
NCBI Gene
retrieved
30 May 2020
Entrez Gene ID
23626
XP_005260438
1 reference
stated in
NCBI Gene
retrieved
30 May 2020
Entrez Gene ID
23626
XP_005260439
1 reference
stated in
NCBI Gene
retrieved
30 May 2020
Entrez Gene ID
23626
XP_011527058
1 reference
stated in
NCBI Gene
retrieved
30 May 2020
Entrez Gene ID
23626
XP_011527059
1 reference
stated in
NCBI Gene
retrieved
30 May 2020
Entrez Gene ID
23626
UniProt protein ID
Q9Y5K1
1 reference
stated in
UniProt
retrieved
13 November 2019
UniProt protein ID
Q9Y5K1
Ensembl protein ID
ENSP00000316034
1 reference
stated in
Ensembl Release 99
Ensembl protein ID
ENSP00000316034
ENSP00000360310
1 reference
stated in
Ensembl Release 99
Ensembl protein ID
ENSP00000360310
ENSP00000360307
1 reference
stated in
Ensembl Release 99
Ensembl protein ID
ENSP00000360307
ENSP00000413185
1 reference
stated in
Ensembl Release 99
Ensembl protein ID
ENSP00000413185
ENSP00000431842
1 reference
stated in
Ensembl Release 99
Ensembl protein ID
ENSP00000431842
Sitelinks
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